Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Jennifer Malon"'
Publikováno v:
BMC Public Health, Vol 18, Iss 1, Pp 1-12 (2018)
Abstract Background Chronic pain is currently a significant health problem in the United States. A comprehensive strategy is needed to increase prevention of chronic pain and to improve care for chronic pain patients. However, development of a succes
Externí odkaz:
https://doaj.org/article/3c47b3a8bfe04023aba5b8d29fdd5fa6
Autor:
Motohiro Ebisawa, Yoko Kataoka, Akio Tanaka, Mizuho Nagao, Elizabeth Laws, Eric Mortensen, Hisakatsu Nawata, Kazuhiko Arima, Daisuke Watanabe, Xin Lu, Jennifer Maloney, Ariane Dubost-Brama, Ashish Bansal, Kenji Yahata
Publikováno v:
Allergology International, Vol 73, Iss 4, Pp 532-542 (2024)
Background: We investigated the efficacy and safety of dupilumab in Japanese patients aged ≥6 months to
Externí odkaz:
https://doaj.org/article/54821419f674416dbe93987dd4251fbf
Autor:
Gil Yosipovitch, MD, Brian S. Kim, MD, Shawn G. Kwatra, MD, Nicholas K. Mollanazar, MD, Sonja Ständer, MD, Takahiro Satoh, MD, PhD, Pedro Mendes-Bastos, MD, Tsen-Fang Tsai, MD, Elizabeth Laws, PhD, Michael C. Nivens, PhD, Jennifer Maloney, MD, Genming Shi, PhD, Ashish Bansal, MD, MBA, Ariane Dubost-Brama, MD
Publikováno v:
JAAD International, Vol 16, Iss , Pp 163-174 (2024)
Background: Phase 3 PRIME/PRIME2 trials independently demonstrated efficacy and an acceptable safety profile of dupilumab adults with moderate-to-severe prurigo nodularis. Objective: To obtain a more precise estimate of onset and magnitude of treatme
Externí odkaz:
https://doaj.org/article/711afba8cadd4d1c95210d2031b7c4d3
Autor:
Mohamed A. Kamal, Matthew P. Kosloski, Ching-Ha Lai, Michael A. Partridge, Manoj Rajadhyaksha, Vanaja Kanamaluru, Ashish Bansal, Arsalan Shabbir, Brad Shumel, Marius Ardeleanu, Susan M. Richards, Hong Yan, Christine R. Xu, Ainara Rodríguez-Marco, Jing Xiao, Faisal A. Khokhar, Guy Gherardi, Elisa Babilonia, Jennifer Maloney, Eric Mortensen, Bolanle Akinlade, Ned Braunstein, Neil Stahl, Albert Torri, John D. Davis, A. Thomas DiCioccio
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundDevelopment of anti-drug antibodies (ADAs) and neutralizing antibodies (NAbs) to monoclonal antibodies may adversely impact pharmacokinetics, efficacy, and/or safety.ObjectiveTo describe incidence, titer, and persistence of dupilumab ADAs a
Externí odkaz:
https://doaj.org/article/261ac4e1c27146febf714be3ad3c22c4
Autor:
Marcus Maurer, Thomas B. Casale, Sarbjit S. Saini, Moshe Ben-Shoshan, Elizabeth Laws, Jennifer Maloney, Deborah Bauer, Allen Radin, Melanie Makhija
Publikováno v:
Dermatology and Therapy, Vol 14, Iss 9, Pp 2427-2441 (2024)
Abstract Introduction In chronic spontaneous urticaria (CSU), interleukin (IL)-4 and IL-13 may promote mast cell activation directly via IL-4 receptor expression, or indirectly via upregulated immunoglobulin E (IgE) production. Dupilumab significantl
Externí odkaz:
https://doaj.org/article/33337bbfe64f445c8596539250ffde4d
Publikováno v:
Investigative Ophthalmology & Visual Science
Purpose Lacrimal gland excision (LGE) has been utilized in several studies to model aqueous tear deficiency, yet sex as a biological variable has not been factored in to these reports. This study compared corneal pathology in male and female mice fol
Publikováno v:
BMC Public Health
BMC Public Health, Vol 18, Iss 1, Pp 1-12 (2018)
BMC Public Health, Vol 18, Iss 1, Pp 1-12 (2018)
Background Chronic pain is currently a significant health problem in the United States. A comprehensive strategy is needed to increase prevention of chronic pain and to improve care for chronic pain patients. However, development of a successful stra
Autor:
Jennifer Malon, Ling Cao
Publikováno v:
The Journal of Immunology. 194:48.18-48.18
CD137L, also known as 4-1BBL, is a co-stimulatory molecule involved in many immune functions. CD137L-mediated signaling can promote monocyte/macrophage proliferation, migration, and production of proinflammatory factors; however, CD137L-mediated micr
Publikováno v:
The Journal of Immunology. 194:74.35-74.35
LP-BM5 retrovirus infection is an established murine model of HIV infection in humans due to that susceptible strains of mice (such as B6) develop immunodeficiency syndrome. Previously, we have shown that infected B6 mice developed peripheral neuropa
Autor:
Jennifer Malon, Ling Cao
Publikováno v:
The Journal of Immunology. 192:181.14-181.14
Previously, we have observed increased expression of Calcitonin Gene Related Peptide (CGRP), a pro-nociceptive neuropeptide, along with selected cytokines and chemokines, in the lumbar spinal cord following spinal nerve L5 transection (L5Tx, a murine