Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Jennifer MacGregor Schafer"'
Autor:
Eun Jig Lee, Vincent L. Cryns, Chunjiang Yu, V. Craig Jordan, Meiling Lu, Feng Chen, Bethany D. Freedman, Jennifer MacGregor Schafer, J. Larry Jameson, Toni Kwan
Publikováno v:
Journal of Biological Chemistry. 280:6742-6751
Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) is a promising cancer therapy that preferentially induces apoptosis in cancer cells. However, many neoplasms are resistant to TRAIL by mechanisms that are poorly understood. Here we demo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7320dad2f39662cf2ce65994ca5a51d4
https://doi.org/10.1074/jbc.m411519200
https://doi.org/10.1074/jbc.m411519200
Autor:
Anait S. Levenson, Jun Horiguchi, Jennifer MacGregor Schafer, V. Craig Jordan, Zehan Chen, Hong Liu
Publikováno v:
The Journal of Steroid Biochemistry and Molecular Biology. 78:41-50
The selective estrogen receptor modulator, 4-hydroxytamoxifen (4-OHT) is a full agonist at the transforming growth factor (TGF) alpha gene in ER negative breast cancer cells stably transfected with ER alpha cDNA (Levenson et al., Br. J. Cancer 77 (19
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42008a7ec4314496689ea4a4b28b2a09
https://doi.org/10.1016/s0960-0760(01)00072-3
https://doi.org/10.1016/s0960-0760(01)00072-3
Publikováno v:
Methods in molecular medicine. 120
Estrogen receptor (ER)-positive MCF-7 breast cancer cell lines can be used both in vitro and in vivo to create anti-hormone resistance. Estrogen withdrawal in vitro results in spontaneous growth of MCF-7 cells. Similarly, culture in the selective ER
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::da857bc70db68860c9b823dafc2940b4
https://pubmed.ncbi.nlm.nih.gov/16491618
https://pubmed.ncbi.nlm.nih.gov/16491618
Publikováno v:
International Journal of Oncology.
Telomerase, a ribonucleoprotein enzyme that functions as a reverse transcriptase, is detected exclusively in immortal cells such as germ cells, stem cells and cancer cells. Telomerase activity is present in almost all human cancers. Telomerase activa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::71ba6e87655eae5ed6eaaf572aa32293
https://doi.org/10.3892/ijo.27.5.1459
https://doi.org/10.3892/ijo.27.5.1459
Publikováno v:
International journal of oncology. 27(5)
Telomerase, a ribonucleoprotein enzyme that functions as a reverse transcriptase, is detected exclusively in immortal cells such as germ cells, stem cells and cancer cells. Telomerase activity is present in almost all human cancers. Telomerase activa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a53c35938dbce00dab525da838e0a41a
https://pubmed.ncbi.nlm.nih.gov/16211243
https://pubmed.ncbi.nlm.nih.gov/16211243
Autor:
V. Craig Jordan, Jennifer MacGregor Schafer, Katherine M. Pease, Anait S. Levenson, David J. Bentrem
Publikováno v:
The Journal of steroid biochemistry and molecular biology. 76(1-5)
Tamoxifen is a valuable therapeutic agent with applications in the treatment and prevention of breast cancer. However, the development of drug resistance limits the usefulness of tamoxifen therapy. One form of drug resistance in breast cancer is tamo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83bb13ca2cc5d1bef5a0ba67cff0d517
https://pubmed.ncbi.nlm.nih.gov/11384864
https://pubmed.ncbi.nlm.nih.gov/11384864