Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Jennifer M. Tremble"'
Autor:
Richard Ellis, Jennifer M. Tremble, Jennifer S. Allen, Ania Skowera, R. David G. Leslie, Mark Peakman, Chloe L. Rackham, Timothy Tree, Colin M. Dayan, B. Lozanoska-Ochser, Karl Pang
Publikováno v:
Diabetes
OBJECTIVE—Immune-mediated destruction of β-cells resulting in type 1 diabetes involves activation of proinflammatory, islet autoreactive T-cells, a process under the control of dendritic cells of the innate immune system. We tested the hypothesis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::049a2bf2873ab2b3c39fa2d3713285c5
https://doi.org/10.2337/db08-0964
https://doi.org/10.2337/db08-0964
Autor:
H. Beyan, Jennifer M. Tremble, Timothy Tree, Mark Peakman, J Lawson, Colin M. Dayan, Richard David Leslie
Publikováno v:
Clinical and experimental immunology. 154(3)
Summary Type I diabetes (T1D) is a T cell-mediated autoimmune disease characterized by loss of tolerance to islet autoantigens, leading to the destruction of insulin-producing beta cells. Peripheral tolerance to self is maintained in health through s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94bdf435ea9320f40b65157bfa84b408
https://pubmed.ncbi.nlm.nih.gov/19037920
https://pubmed.ncbi.nlm.nih.gov/19037920
Autor:
Mark Peakman, Amanda J. Bishop, Thomas P. Astill, Colin M. Dayan, Jennifer M. Tremble, Timothy Tree, Bart O. Roep, Sefina Arif
Publikováno v:
The Journal of clinical investigation. 113(3)
According to the quality of response they mediate, autoreactive T cells recognizing islet beta cell peptides could represent both disease effectors in the development of type 1 diabetes (T1DM) and directors of tolerance in nondiabetic individuals or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18b2ba93d4e0e62543a93881dab8ffae
https://pubmed.ncbi.nlm.nih.gov/14755329
https://pubmed.ncbi.nlm.nih.gov/14755329
Autor:
Jennifer M. Tremble, J. P. Banga, Kathryn Haskins, John C. Hutton, K. Docherty, W. M. Macfarlane, Roger F.L. James, Timothy Tree, D. O’Byrne
SUMMARYType 1 diabetes is a T cell-mediated autoimmune disease where a number of islet β-cell target autoantigens have been characterized on the basis of reactivity with autoantibodies. Nevertheless, there remains uncertainty of the nature of anothe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6763e5cf693fbcd1d718ad7f76f3b921
https://europepmc.org/articles/PMC1905664/
https://europepmc.org/articles/PMC1905664/
