Zobrazeno 1 - 10 of 22 pro vyhledávání: '"Jennifer M. Rothberg"'
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Supplementary Figure 1 from Acidity Generated by the Tumor Microenvironment Drives Local Invasion
Autor: Robert J. Gillies, Robert A. Gatenby, Joseph Johnson, Bonnie F. Sloane, Jennifer M. Rothberg, Yoganand Balagurunathan, Kate Bailey, Arig Ibrahim-Hashim, Heather H. Cornnell, Jonathan Wojtkowiak, Mark Lloyd, Tingan Chen, Veronica Estrella
PDF file - 287K, Figure S1: Photomicrographs of cells in this study. HMEC, HCT116/GFP and MDAmb231 cells were grown to 70-80% confluency. Samples were then viewed with an automated Zeiss Observer Z.1 inverted microscope through a 10x /0.3NA or 20x/0.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66b423cd5b0bf700d7b220e59f853176
https://doi.org/10.1158/0008-5472.22399074
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3
Supplementary Figure 2 from Chronic Autophagy Is a Cellular Adaptation to Tumor Acidic pH Microenvironments
Autor: Robert J. Gillies, Bonnie F. Sloane, Mark C. Lloyd, Joshua B. Proemsey, Edward Haller, Karla J. Schramm, Virendra Kumar, Jennifer M. Rothberg, Jonathan W. Wojtkowiak
PDF file - 241K, Histological analysis of LC3 spatial expression patterns in relation to pimonidazole hydrochloride (Hypoxia) and Glut1 expression. MDA-MB-231 MFP tumor was histologically stained for LC3, Glut1, and pimonidazole hydrochloride. Pixel
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88eb7e9cdf609d834a80106a3be4b0fc
https://doi.org/10.1158/0008-5472.22391631
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4
Supplementary Figure 5 from Acidity Generated by the Tumor Microenvironment Drives Local Invasion
Autor: Robert J. Gillies, Robert A. Gatenby, Joseph Johnson, Bonnie F. Sloane, Jennifer M. Rothberg, Yoganand Balagurunathan, Kate Bailey, Arig Ibrahim-Hashim, Heather H. Cornnell, Jonathan Wojtkowiak, Mark Lloyd, Tingan Chen, Veronica Estrella
PDF file - 43K, Figure S5: Relation between tumor growth and pH for all 5 mice. Data for all 5 mice were parsed as in figure 2D wherein the growth (in pixels) and pH were calculated every 22.5o of arc. These data show that growth increased with decre
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d3643bc931def5225ab0dc040c7c16b
https://doi.org/10.1158/0008-5472.22399059.v1
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5
Supplementary Figure 3 from Chronic Autophagy Is a Cellular Adaptation to Tumor Acidic pH Microenvironments
Autor: Robert J. Gillies, Bonnie F. Sloane, Mark C. Lloyd, Joshua B. Proemsey, Edward Haller, Karla J. Schramm, Virendra Kumar, Jennifer M. Rothberg, Jonathan W. Wojtkowiak
PDF file - 431K, Histological analysis of in-vivo LC3 expression in HS766T subcutaneous tumors buffered with sodium bicarbonate. (A) Whole cell lysates from HS766T cells cultured at neutral pH 7.4 or pH 6.7 for 48 hours were analyzed for LC3-II expre
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c5bccdfdb9906bb431380bcab3b43fe
https://doi.org/10.1158/0008-5472.22391628
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6
Supplementary Figure 4 from Acidity Generated by the Tumor Microenvironment Drives Local Invasion
Autor: Robert J. Gillies, Robert A. Gatenby, Joseph Johnson, Bonnie F. Sloane, Jennifer M. Rothberg, Yoganand Balagurunathan, Kate Bailey, Arig Ibrahim-Hashim, Heather H. Cornnell, Jonathan Wojtkowiak, Mark Lloyd, Tingan Chen, Veronica Estrella
PDF file - 77K, Figure S4: Quantification of tumor growth. Images are shown for mouse tumor #23 on day 4 (green) and day 14 (red). Images were co-registered using the ring clip of the DWC as a fiducial. The centroid of the tumor on day 4 was calculat
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05ccb1868c0e0fbf6938adb90ec091da
https://doi.org/10.1158/0008-5472.22399062
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Supplementary Figure 2 from Acidity Generated by the Tumor Microenvironment Drives Local Invasion
Autor: Robert J. Gillies, Robert A. Gatenby, Joseph Johnson, Bonnie F. Sloane, Jennifer M. Rothberg, Yoganand Balagurunathan, Kate Bailey, Arig Ibrahim-Hashim, Heather H. Cornnell, Jonathan Wojtkowiak, Mark Lloyd, Tingan Chen, Veronica Estrella
PDF file - 45K, Figure S2: Comparison of normal vs tumor cells by size. Using these phase contrast images, ROI were chosen and area of cells was determined by pixel number using Image-Pro Plus v6.2. Once area was measured, data analysis revealed stat
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37448546f3bf3de19ab1157618753234
https://doi.org/10.1158/0008-5472.22399068.v1
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Supplementary Figure 6 from Acidity Generated by the Tumor Microenvironment Drives Local Invasion
Autor: Robert J. Gillies, Robert A. Gatenby, Joseph Johnson, Bonnie F. Sloane, Jennifer M. Rothberg, Yoganand Balagurunathan, Kate Bailey, Arig Ibrahim-Hashim, Heather H. Cornnell, Jonathan Wojtkowiak, Mark Lloyd, Tingan Chen, Veronica Estrella
PDF file - 50K, Figure S6: Ex vivo comparison of vessel density in stroma vs tumor tissue. Using the Image Scope v7.1 regions of viable tumor were manually selected. 200�m micrometers were placed around the circumference of the tumor region perpend
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0801ba81001cf9150b7b2f3ea9757287
https://doi.org/10.1158/0008-5472.22399056
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