Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Jennifer M. Roth"'
Publikováno v:
Cancer Research. 68:4666-4673
Cathepsin D (CD) up-regulation has been associated with human malignancy and poor prognosis. Thrombin up-regulated CD mRNA and protein in eight tumor cell lines as well as in human umbilical vascular endothelial cells (HUVEC). Thrombin increased the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b8e05450122bfb5df9f9fb2e954db26
https://doi.org/10.1158/0008-5472.can-07-6276
https://doi.org/10.1158/0008-5472.can-07-6276
Autor:
Paul J. Gagne, Silvia C. Formenti, Peter C. Brooks, Maresa Caunt, Alexandra Cretu, Desiree Policarpio, Leonard Liebes, Abebe Akalu, Jennifer M. Roth
Publikováno v:
Clinical Cancer Research. 13:3068-3078
Purpose: The importance of cellular communication with the extracellular matrix in regulating cellular invasion is well established. Selective disruption of communication links between cells and the local microenvironment by specifically targeting no
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4d5ecee35ff51fb6ad6f22f6662fc49
https://doi.org/10.1158/1078-0432.ccr-06-2342
https://doi.org/10.1158/1078-0432.ccr-06-2342
Autor:
Shannon M. MacDonald, Danielle Morais, Maresa Caunt, Silvia C. Formenti, Michael T Buckley, Sandhya Xavier, Abebe Akalu, Peter C. Brooks, Leonard Liebes, Jennifer M. Roth
Publikováno v:
International Journal of Radiation Oncology*Biology*Physics. 65:517-527
Purpose: To determine whether para-aminobenzoic acid (PABA) alters the sensitivity of tumor cells to ionizing radiation in vitro and in vivo . Methods and Materials: Cellular proliferation was assessed by WST-1 assays. The effects of PABA and radiati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43f5b025dc76201161fe3367ab4808cd
https://doi.org/10.1016/j.ijrobp.2006.01.010
https://doi.org/10.1016/j.ijrobp.2006.01.010
Autor:
Leonard Liebes, Peter C. Brooks, Bruce Ng, Shannon M. MacDonald, Jennifer M. Roth, Silvia C. Formenti, Desiree Policarpio, Anat Zelmanovich, Abebe Akalu
Publikováno v:
The American Journal of Pathology. 166:901-911
Cellular interaction with the extracellular matrix is thought to be a critical event in controlling angiogenesis and tumor growth. In our previous studies, genetically distinct noncollagenous (NC) domains of type-IV collagen were shown to interact wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40d400f89df9bd05b216e9669e1099f4
https://doi.org/10.1016/s0002-9440(10)62310-3
https://doi.org/10.1016/s0002-9440(10)62310-3
Autor:
Silvia C. Formenti, Daniel Broek, K. DeWyngaert, Jennifer M. Roth, Stella C. Lymberis, Peter C. Brooks
Publikováno v:
International Journal of Radiation Oncology*Biology*Physics. 54:1194-1201
Purpose: The majority of the research on the biologic effects of ionizing radiation has focused on the impact of radiation on cells in terms of gene expression, DNA damage, and cytotoxicity. In comparison, little information is available concerning t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1295f27c26706c578cf3379653663d5
https://doi.org/10.1016/s0360-3016(02)03748-3
https://doi.org/10.1016/s0360-3016(02)03748-3
Autor:
Jennifer M. Roth, Jessica Correnti
Publikováno v:
Journal of PeriAnesthesia Nursing. 30:e13-e14
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c537f6262aae965abe403fc6ef8e5d41
https://doi.org/10.1016/j.jopan.2015.05.040
https://doi.org/10.1016/j.jopan.2015.05.040
Publikováno v:
The Tumor Microenvironment ISBN: 9781441966148
As with most complex biological processes, angiogenesis requires the integration of a number of molecular signaling networks to coordinate multiple cues from both the extracellular tissue microenvironment as well as the cell’s interior. Thus an imp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a6c48abe23f21cd90f49a18553abd994
https://doi.org/10.1007/978-1-4419-6615-5_29
https://doi.org/10.1007/978-1-4419-6615-5_29
Autor:
Maresa Caunt, Peter C. Brooks, Jennifer M. Roth, Leonard Liebes, Desiree Policarpio, Abebe Akalu
Publikováno v:
Cancer research. 67(9)
Angiogenesis and tumor metastasis depend on extracellular matrix (ECM) remodeling and subsequent cellular interactions with these modified proteins. An in-depth understanding of how both endothelial and tumor cells use matrix-immobilized cryptic ECM
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8ab3fe8153f95cfe11b0784c9bb0c8e
https://pubmed.ncbi.nlm.nih.gov/17483349
https://pubmed.ncbi.nlm.nih.gov/17483349
Autor:
Ellinor Oxelmark, S. Braunstein, Michael J. Garabedian, Robert J. Schneider, Jennifer M. Roth, Peter C. Brooks
Publikováno v:
Molecular and cellular biology. 26(14)
The cochaperone p23 plays an important role in estrogen receptor alpha (ER) signal transduction. In this study, we investigated how p23 regulates ER target gene activation and affects tumor growth and progression. Remarkably, we found that changes in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::332ca08c33f75591042acd1aed9377dd
https://pubmed.ncbi.nlm.nih.gov/16809759
https://pubmed.ncbi.nlm.nih.gov/16809759
Autor:
Xiaolu Li, Maresa Caunt, Desiree Policarpio, Jennifer M. Roth, Paul J. Gagne, Silvia C. Formenti, Abebe Akalu, Alexandra Cretu, Peter C. Brooks
Publikováno v:
The American journal of pathology. 168(5)
Metastasis from the primary tumor to distant sites involves an array of molecules that function in an integrated manner. Proteolytic remodeling and subsequent tumor cell interactions with the extracellular matrix regulate tumor invasion. In previous
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15f8cfe0da7677b1247028b36fe4a5b7
https://pubmed.ncbi.nlm.nih.gov/16651624
https://pubmed.ncbi.nlm.nih.gov/16651624