Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Jennifer M. Pell"'
Publikováno v:
Journal of Cell Science. 126:565-579
Summary Tissue generation and repair requires a stepwise process of cell fate restriction to ensure that adult stem cells differentiate in a timely and appropriate manner. A crucial role has been implicated for Polycomb-group (PcG) proteins and the H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6660f472f015e59257b1de3a38394df
https://doi.org/10.1242/jcs.114843
https://doi.org/10.1242/jcs.114843
Autor:
Sam Woodhouse, Jennifer M. Pell, Rachel A. Watson, Heather J. Spence, Emma L. Wiggins, Brad W. Ozanne, Ruth A. Cosgrove, Anja C. Drozd, Camille W. Paxton
Publikováno v:
American Journal of Physiology-Cell Physiology. 300:C1345-C1355
The BTB-Kelch protein Krp1 is highly and specifically expressed in skeletal muscle, where it is proposed to have a role in myofibril formation. We observed significant upregulation of Krp1 in C2 cells early in myoblast differentiation, well before my
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0eaa3a3739cb3cee317ccc9385459ac1
https://doi.org/10.1152/ajpcell.00321.2010
https://doi.org/10.1152/ajpcell.00321.2010
Autor:
Laura J. Cobb, Dervis A. Salih, Gyanendra Tripathi, Anja C. Drozd, Ruth A. Cosgrove, Jennifer M. Pell
Publikováno v:
The FASEB Journal. 23:2616-2626
IGF activity is regulated tightly by a family of IGF binding proteins (IGFBPs). IGFBP-5 is the most conserved of these and is up-regulated significantly during differentiation of several key lineages and in some cancers. The function of IGFBP-5 in th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18059dd8c98c655192468f184436d57f
https://doi.org/10.1096/fj.08-114124
https://doi.org/10.1096/fj.08-114124
Autor:
Jennifer M. Pell, Ivelisse Gonzalez, Fiona A. Lovett, Gyanendra Tripathi, Cathy Holding, Laura J. Cobb, Emma J. Carter, Dervis A. Salih
Publikováno v:
Molecular and Cellular Biology. 24:3607-3622
Activation of either the phosphatidylinositol 3-kinase (PI 3-kinase)/Akt or the p38 mitogen-activated protein kinase (MAPK) signaling pathways accelerates myogenesis but only when the reciprocal pathway is functional. We therefore examined the hypoth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69b9036e6d799080237f6003e448dcbc
https://doi.org/10.1128/mcb.24.9.3607-3622.2004
https://doi.org/10.1128/mcb.24.9.3607-3622.2004
Autor:
Laura J. Cobb, Dervis A. Salih, M. Ivelisse Gonzalez, Cathy Holding, Gyanendra Tripathi, Emma J. Carter, Jennifer M. Pell, Joan E. Eisemann, Tadge Szestak
Publikováno v:
Proceedings of the National Academy of Sciences. 101:4314-4319
The insulin-like growth factors (IGFs) are essential for development; bioavailable IGF is tightly regulated by six related IGF-binding proteins (IGFBPs). Igfbp5 is the most conserved and is developmentally up-regulated in key lineages and pathologies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8342218429a18b9ad83aa8cf75f1f743
https://doi.org/10.1073/pnas.0400230101
https://doi.org/10.1073/pnas.0400230101
Publikováno v:
Journal of Animal Science. 80:1074-1082
The establishment of a GH-responsive endocrine IGF-I network is essential for the regulation of postnatal growth. Transcripts of exons 1 and 2 of the mammalian IGF-I gene are alternately spliced onto exon 3, generating class 1 and class 2 mRNA, respe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::706443421a792f4aa8691afc102823a0
https://doi.org/10.2527/2002.8041074x
https://doi.org/10.2527/2002.8041074x
Autor:
Paul N. Schofield, Jennifer M. Pell
Publikováno v:
Seminars in Neonatology. 4:79-91
Recent advances in our understanding of the molecular and cellular processes underlying myogenesis have generated a new paradigm for the understanding of vertebrate organogenesis. In this review, we examine the role of intrinsic and extrinsic cues fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f8175909ccfd73e67b7a3ef369c8fb13
https://doi.org/10.1016/s1084-2756(99)80010-4
https://doi.org/10.1016/s1084-2756(99)80010-4
Autor:
Thomas J. McDonald, Jim Petrik, Wolf Reik, Wendy Dean, Jennifer M. Pell, Edith Arany, David J. Hill
Publikováno v:
Endocrinology. 140:2353-2363
We have used an insulin-like growth factor (IGF)-II transgenic mouse model in which mouse IGF-II is widely overexpressed, resulting in increased fetal size and selective organ overgrowth, to investigate the effects on the development of the endocrine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bcf7ebab189f6bd6d38ff89533983cc9
https://doi.org/10.1210/endo.140.5.6732
https://doi.org/10.1210/endo.140.5.6732
Autor:
Jennifer M. Pell, Laura A. Maile, Su Xu, Janet K. Fernihough, Sian C. Cwyfan-Hughes, Jeffrey M P Holly
Publikováno v:
Endocrinology. 139:4772-4781
Circulating insulin-like growth factor binding protein-3 (IGFBP-3) proteolytic activity is normally low but increases in serum from pregnant women and from patients with various pathologies. In contrast, we have recently reported that outside the cir
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afdcd523691dd1ba9416de8bec74f2cb
https://doi.org/10.1210/endo.139.12.6359
https://doi.org/10.1210/endo.139.12.6359
Autor:
R.A. Hill, Jennifer M. Pell
Publikováno v:
Endocrinology. 139:1278-1287
We have previously demonstrated the ability of a polyclonal antibody raised against human insulin-like growth factor I (IGF-I) to potentiate, rather than inhibit, the growth-promoting activity of IGF-I. The anti-IGF-I Ig had a modest affinity for IGF
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::62586369d0b093fcde1bd6acaac0fcec
https://doi.org/10.1210/endo.139.3.5804
https://doi.org/10.1210/endo.139.3.5804