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pro vyhledávání: '"Jennifer M. Keating"'
Autor:
Joseph P. Biggane, Jessica A. Kjemhus, Matthew J. Picklo, Jennifer M. Keating, Thomas P. Gonnella
Publikováno v:
Chemico-biological interactions. 202(1-3)
Aldehyde dehydrogenase 1 (ALDH1A1) catalyzes the oxidation of toxic aldehydes to carboxylic acids. Physiologic levels of Mg(2+) ions decrease ALDH1 activity in part by increasing NADH binding affinity to the enzyme. By using time-resolved fluorescenc