Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Jennifer M. Edwards"'
Autor:
David J. Read, Patrick M. Sexton, Arthur Christopoulos, Nicholas Verity, Timothy Macedo-Hatch, Joern R. Steinert, Adrian J. Mogg, Jürgen Wess, Andrew B. Tobin, Julie-Myrtille Bourgognon, David J. White, Giovanna R. Mallucci, Sophie J. Bradley, Helen E. Sanger, Robert Pawlak, Lisa M. Broad, Jennifer M. Edwards, Julie A. Moreno, Christian C. Felder, Adrian J. Butcher, Colin Molloy
Publikováno v:
The Journal of Clinical Investigation
Journal of Clinical Investigation
Journal of Clinical Investigation
The current frontline symptomatic treatment for Alzheimer's disease (AD) is whole-body upregulation of cholinergic transmission via inhibition of acetylcholinesterase. This approach leads to profound dose-related adverse effects. An alternative strat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b41ed02cf8e5bdc990817b6eee0bf0eb
https://doi.org/10.1172/jci87526
https://doi.org/10.1172/jci87526
Autor:
Sally A. Edwards, Nathalie Conte, Allan Bradley, Charles T. Foster, Rajinder Singh, Shaun M. Cowley, Oliver M. Dovey, George S. Vassiliou, Jennifer M. Edwards
Publikováno v:
Blood. 121:1335-1344
Histone deacetylase 1 and 2 (HDAC1/2) regulate chromatin structure as the catalytic core of the Sin3A, NuRD and CoREST co-repressor complexes. To better understand the key pathways regulated by HDAC1/2 in the adaptive immune system and inform their e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70279308ed6e508739080a7bcad1267e
https://doi.org/10.1182/blood-2012-07-441949
https://doi.org/10.1182/blood-2012-07-441949
Autor:
Sharad Mistry, Phillip McWilliams, Andrew B. Tobin, Kok Choi Kong, Andrew R. Bottrill, Jennifer M. Edwards, Rudi Prihandoko, Adrian J. Butcher
Publikováno v:
The Journal of Biological Chemistry
G-protein-coupled receptors are hyper-phosphorylated in a process that controls receptor coupling to downstream signaling pathways. The pattern of receptor phosphorylation has been proposed to generate a "bar code" that can be varied in a tissue-spec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a19d79161db6d46ceef18ce701ca59f
http://europepmc.org/articles/PMC3064205
http://europepmc.org/articles/PMC3064205
Autor:
Adrian J. Butcher, Simon M. Brooke, Adrian J. Mogg, Jennifer M. Edwards, Rudi Prihandoko, Julie-Myrtille Bourgognon, Andrew R. Bottrill, Sophie J. Bradley, Christian C. Felder, Andrew B. Tobin, Lisa M. Broad, R. A. John Challiss, Timothy Macedo-Hatch
Publikováno v:
The Journal of Biological Chemistry
Establishing the in vivo activation status of G protein-coupled receptors would not only indicate physiological roles of G protein-coupled receptors but would also aid drug discovery by establishing drug/receptor engagement. Here, we develop a phosph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::267661159099c767f293cee6b40d99fc
https://pubmed.ncbi.nlm.nih.gov/26826123
https://pubmed.ncbi.nlm.nih.gov/26826123
Publikováno v:
Neuropharmacology
Parkinson's disease (PD) shows a complex etiology, where both genetic and environmental factors contribute to initiation and advance of pathology. Mitochondrial dysfunction and mutation of genes implicated in mitochondria quality control are recogniz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f8ea624511a66115264cd4f9614c5fa
https://doi.org/10.1016/j.neuropharm.2013.10.009
https://doi.org/10.1016/j.neuropharm.2013.10.009
Autor:
Steve Stoner, Daniel R. Touchette, Margaret E. McGuinness, Jennifer M. Edwards, Kathy L. Ketchum, David Shute
Publikováno v:
Pharmacy Practice (Granada) v.6 n.1 2008
SciELO España. Revistas Científicas Españolas de Ciencias de la Salud
instname
Pharmacy Practice (Granada), Volume: 6, Issue: 1, Pages: 43-50, Published: MAR 2008
Pharmacy Practice
Scopus-Elsevier
SciELO España. Revistas Científicas Españolas de Ciencias de la Salud
instname
Pharmacy Practice (Granada), Volume: 6, Issue: 1, Pages: 43-50, Published: MAR 2008
Pharmacy Practice
Scopus-Elsevier
Atrial fibrillation affects an estimated 5 million Americans and accounts for approximately 15% of all strokes. Few studies have successfully addressed patient screening, assessment, and introduction of appropriate antithrombotic therapy in patients
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e96832f27359384d23b56b328ef79b3
https://doi.org/10.4321/s1886-36552008000100007
https://doi.org/10.4321/s1886-36552008000100007
Autor:
Craig A. Pedersen, Michael D. Sanborn, Jill T. Robke, Rita Munley Gallagher, Bruce J. Fried, Jennifer M. Edwards, Stacey Posner, Roland A. Patry, Jonathan C. Peck, Saralyn Mark, Patricia Deyton, Colleen O’Malley, Lea S. Eiland, Lynnae M. Mahaney
Publikováno v:
American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists. 64(12)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::391d584b30553c3998530cac3540a3eb
https://pubmed.ncbi.nlm.nih.gov/17563047
https://pubmed.ncbi.nlm.nih.gov/17563047
Publikováno v:
The FASEB Journal. 20
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::980c2940c3e42c2ae4581cca0cf1e5c7
https://doi.org/10.1096/fasebj.20.4.a337-a
https://doi.org/10.1096/fasebj.20.4.a337-a
Autor:
Gerald M. Cohen, Marion MacFarlane, Jennifer M. Edwards, Rosemary A. Walker, Shambhavi Naik, Roshna Mistry, Davina Twiddy
Publikováno v:
Toxicology. 290:141-142
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::06681a4b93bd40ba9d4141e9978f2609
https://doi.org/10.1016/j.tox.2011.09.071
https://doi.org/10.1016/j.tox.2011.09.071
Autor:
Jennifer M. Edwards, James A. Trovato
Publikováno v:
American Journal of Health-System Pharmacy. 61:1956-1957
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a912ce921ea2809bbf8c19c1fa5b6e75
https://doi.org/10.1093/ajhp/61.18.1956
https://doi.org/10.1093/ajhp/61.18.1956