Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Jennifer M. Crawford"'
Autor:
Jennifer M. Crawford, Tobias Gensch, Matthew S. Sigman, Jennifer M. Elward, Janelle E. Steves
Publikováno v:
Organic Process Research & Development. 26:1115-1123
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4639bdcfbd54c0a94e83823540574060
https://doi.org/10.1021/acs.oprd.1c00357
https://doi.org/10.1021/acs.oprd.1c00357
Publikováno v:
Accounts of chemical research, vol 54, iss 16
Acc Chem Res
Acc Chem Res
ConspectusAt the heart of synthetic chemistry is the holy grail of predictable catalyst design. In particular, researchers involved in reaction development in asymmetric catalysis have pursued a variety of strategies toward this goal. This is driven
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7dcabf3ed384338ee33b6749915f4362
https://escholarship.org/uc/item/3zw5c97g
https://escholarship.org/uc/item/3zw5c97g
Autor:
Jennifer M. Crawford, F. Dean Toste, Scott J. Miller, Roxane Jacob, Jolene P. Reid, Yongseok Kwon, Junqi Li, Matthew S. Sigman
Publikováno v:
Journal of the American Chemical Society. 141:6698-6705
Catalysts that control stereochemistry are prized tools in chemical synthesis. When an effective catalyst is found, it is often explored for other types of reactions, frequently under the auspices of different mechanisms. As successes mount, a unique
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9694d647c4bc00b26af94f96c31fa974
https://doi.org/10.1021/jacs.9b01911
https://doi.org/10.1021/jacs.9b01911
Autor:
Matthew S. Sigman, Jennifer M. Crawford, Scott J. Miller, Anthony J. Metrano, Elizabeth A Stone
Publikováno v:
Journal of the American Chemical Society. 140:868-871
We report the development of a method to parameterize and predict the performance of structurally flexible β-turn-containing peptide catalysts, using the atroposelective bromination of 3-arylquinazolin-4(3H)-ones as a case study. The multivariate co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7990fff44fd3ceeb3f3df09517043a1c
https://doi.org/10.1021/jacs.7b11303
https://doi.org/10.1021/jacs.7b11303
Publikováno v:
Anaesthesia and intensive care. 47(2)
Clonidine has been used successfully to prolong the duration of action of local anaesthetics in peripheral nerve blocks, but its mechanism of action in this setting remains unclear. Some studies suggest that clonidine exerts a vasoconstrictor effect,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45a7f8263bdfb29156ee161409233337
https://pubmed.ncbi.nlm.nih.gov/31070463
https://pubmed.ncbi.nlm.nih.gov/31070463
Traditionally, highly selective low molecular weight catalysts have been designed to contain rigidifying structural elements. As a result, many proposed stereochemical models rely on steric repulsion for explaining the observed selectivity. Recently,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::961d4f47513f95383d764bf2aac8c2d6
https://europepmc.org/articles/PMC6590688/
https://europepmc.org/articles/PMC6590688/
Autor:
Emily K. Reeves, Bryce K. Sadarananda, Dipannita Kalyani, Kyle E. Shelton, Jennifer M. Crawford
Publikováno v:
Organic Chemistry Frontiers. 2:726-729
This manuscript describes a Ni-catalyzed method for the direct arylation of azoles using benzoates. Perfluorophenyl and 2-nitrobenzoates participate in these reactions to afford the corresponding products in modest to good yields. The efficiency of t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c31bef6404dc284d91c4b5e6b0d47490
https://doi.org/10.1039/c5qo00040h
https://doi.org/10.1039/c5qo00040h
Publikováno v:
ChemInform. 47
An enantioselective, intermolecular dehydrogenative Heck arylation of trisubstituted alkenes to construct remote quaternary stereocenters has been developed. Using a new chiral pyridine oxazoline ligand, good to high enantioselectivity is achieved fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::783cca115b0285ffdb917ef173d34084
https://doi.org/10.1002/chin.201623132
https://doi.org/10.1002/chin.201623132
An enantioselective, intermolecular dehydrogenative Heck arylation of trisubstituted alkenes to construct remote quaternary stereocenters has been developed. Using a new chiral pyridine oxazoline ligand, good to high enantioselectivity is achieved fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b951feed9fea74fb5b9cbdf7f6f5550a
https://europepmc.org/articles/PMC5039010/
https://europepmc.org/articles/PMC5039010/
Publikováno v:
Journal of Pediatric Surgery. 44:413-416
Background Controversy persists surrounding early management of disorders of sex development. We assessed genital appearance, gender identity, and quality of life in prepubertal children who have had early surgical intervention. Methods Children trea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55fa96f3398d74614614646ab91d3ce7
https://doi.org/10.1016/j.jpedsurg.2008.10.101
https://doi.org/10.1016/j.jpedsurg.2008.10.101