Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Jennifer M. Cherone"'
Publikováno v:
Experimental Hematology. 108:16-25
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a662a7e6a811ff3f2805a6daf22fc38a
https://doi.org/10.1016/j.exphem.2022.01.007
https://doi.org/10.1016/j.exphem.2022.01.007
Publikováno v:
Experimental hematology. 108
The functional impact of integrin expression in erythropoiesis has been previously emphasized through its decisive influence on erythroid cell-microenvironment (matrix and cellular) interactions, especially under conditions of stress. Beyond that, in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6341590c36ca0805b928405a502e383b
https://pubmed.ncbi.nlm.nih.gov/35227527
https://pubmed.ncbi.nlm.nih.gov/35227527
Publikováno v:
Genome Res
MicroRNAs (miRNAs) play roles in diverse developmental and disease processes. Distinct miRNAs have hundreds to thousands of conserved mRNA binding sites but typically direct only modest repression via single sites. Cotargeting of individual mRNAs by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2aab2a991b27f1c0b815f31779832a0d
https://doi.org/10.1101/gr.249201.119
https://doi.org/10.1101/gr.249201.119
Autor:
Yasaman Ataei, Larry Park, D. James Surmeier, B. Joseph Vu, Seung Kwak, Richard T. Surosky, Anand Narayanan, David A. Shivak, Josee Laganiere, Christer Halldin, Andrea Varrone, Matthew C. Mendel, Karsten Tillack, Lei Zhang, Bryan Zeitler, Dmitry Guschin, Lexi Kopan, Sarah J. Hinkley, Kimberly Marlen, Jocelynn R. Pearl, Qi Yu, Taneli Heikkinen, Annette Gärtner, Yalda Sedaghat, Christina Thiede, Miklós Tóth, Jennifer M. Cherone, David Paschon, Jyothisri Kondapalli, Andrea E. Kudwa, Ladislav Mrzljak, Rainier Amora, Kimmo Lehtimäki, Edward J. Rebar, Lenke Tari, Ignacio Munoz-Sanjuan, Jeffrey C. Miller, Sylvie Ramboz, Marie Svedberg, Steven Froelich, Irina Ankoudinova, Philip D. Gregory, Stephen Lam, Michelle Day, Jonathan Bard, Hoang Oanh B. Nguyen, Fyodor D. Urnov, Davis Li, Jenny Haggkvist, H. Steve Zhang, Guijuan Qiao
Publikováno v:
Nature Medicine. 25:1131-1142
Huntington’s disease (HD) is a dominantly inherited neurodegenerative disorder caused by a CAG trinucleotide expansion in the huntingtin gene (HTT), which codes for the pathologic mutant HTT (mHTT) protein. Since normal HTT is thought to be importa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d19307c1ae395108f0cf1b74fb590fb6
https://doi.org/10.1038/s41591-019-0478-3
https://doi.org/10.1038/s41591-019-0478-3
Autor:
Bryan, Zeitler, Steven, Froelich, Kimberly, Marlen, David A, Shivak, Qi, Yu, Davis, Li, Jocelynn R, Pearl, Jeffrey C, Miller, Lei, Zhang, David E, Paschon, Sarah J, Hinkley, Irina, Ankoudinova, Stephen, Lam, Dmitry, Guschin, Lexi, Kopan, Jennifer M, Cherone, Hoang-Oanh B, Nguyen, Guijuan, Qiao, Yasaman, Ataei, Matthew C, Mendel, Rainier, Amora, Richard, Surosky, Josee, Laganiere, B Joseph, Vu, Anand, Narayanan, Yalda, Sedaghat, Karsten, Tillack, Christina, Thiede, Annette, Gärtner, Seung, Kwak, Jonathan, Bard, Ladislav, Mrzljak, Larry, Park, Taneli, Heikkinen, Kimmo K, Lehtimäki, Marie M, Svedberg, Jenny, Häggkvist, Lenke, Tari, Miklós, Tóth, Andrea, Varrone, Christer, Halldin, Andrea E, Kudwa, Sylvie, Ramboz, Michelle, Day, Jyothisri, Kondapalli, D James, Surmeier, Fyodor D, Urnov, Philip D, Gregory, Edward J, Rebar, Ignacio, Muñoz-Sanjuán, H Steve, Zhang
Publikováno v:
Nature medicine. 25(7)
Huntington's disease (HD) is a dominantly inherited neurodegenerative disorder caused by a CAG trinucleotide expansion in the huntingtin gene (HTT), which codes for the pathologic mutant HTT (mHTT) protein. Since normal HTT is thought to be important
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4d3620bad8fe21aa64bd37ef53578561
https://pubmed.ncbi.nlm.nih.gov/31263285
https://pubmed.ncbi.nlm.nih.gov/31263285
Autor:
Yolanda Santiago, Sarah J. Hinkley, John P. Cassady, Qing Gao, Samira Kiani, Lei Zhang, Rudolf Jaenisch, Edward J. Rebar, Dirk Hockemeyer, Bryan Zeitler, Haoyi Wang, Jeffrey C. Miller, Jennifer M. Cherone, Fyodor D. Urnov, Christine S. Lai, Philip D. Gregory, Xiangdong Meng, Gregory J. Cost
Publikováno v:
Nature biotechnology
Targeted genetic engineering of human pluripotent cells is a prerequisite for exploiting their full potential. Such genetic manipulations can be achieved using site-specific nucleases. Here we engineered transcription activator-like effector nuclease
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2029363c199e97563f28bbf1ee8e846d
https://doi.org/10.1038/nbt.1927
https://doi.org/10.1038/nbt.1927
Autor:
Yannick Doyon, Aaron T. Cheng, Philip D. Gregory, Edward J. Rebar, Jeffrey B. Doyon, Thuy D Vo, Jackie Cheng, Bryan Zeitler, David G. Drubin, David Paschon, Fyodor D. Urnov, Lei Zhang, Jeffrey C. Miller, Jennifer M. Cherone, Andrew H. Lee, Yolanda Santiago
Publikováno v:
Nature Cell Biology. 13:331-337
Clathrin-mediated endocytosis (CME) is the best-studied pathway by which cells selectively internalize molecules from the plasma membrane and surrounding environment. Previous live-cell imaging studies using ectopically overexpressed fluorescent fusi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b21f3f0820e07fb2e424bb5a34634b9a
https://doi.org/10.1038/ncb2175
https://doi.org/10.1038/ncb2175
Autor:
Thomas A. Cooper, Daniel J. Treacy, Amanda J. Ward, Christopher B. Burge, Eric T. Wang, Tanvi Saxena, Peter Freese, Jennifer M. Cherone, Jimena Giudice, Nicole J. Lambert, Thomas T. Wang
Publikováno v:
Cold Spring Harbor Laboratory Press
RNA binding proteins of the conserved CUGBP1, Elav-like factor (CELF) family contribute to heart and skeletal muscle development and are implicated in myotonic dystrophy (DM). To understand their genome-wide functions, we analyzed the transcriptome d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89afe7108bc1c4345d023f74cb53e577
https://europepmc.org/articles/PMC4448682/
https://europepmc.org/articles/PMC4448682/
Autor:
Andrew H. Lee, Catherine Ngo, John J. Young, Jeffrey C. Miller, Yannick Doyon, Richard M. Harland, Lei Zhang, Bryan Zeitler, Edward J. Rebar, Philip D. Gregory, Farhoud Faraji, Irina Ankoudinova, Dmitry Guschin, David Paschon, Jennifer M. Cherone, Fyodor D. Urnov
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 108(17)
The frog Xenopus , an important research organism in cell and developmental biology, currently lacks tools for targeted mutagenesis. Here, we address this problem by genome editing with zinc-finger nucleases (ZFNs). ZFNs directed against an eGFP tran
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9093d4cd6a5828f0546cf775ccf2d5ed
https://pubmed.ncbi.nlm.nih.gov/21471457
https://pubmed.ncbi.nlm.nih.gov/21471457