Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Jennifer M. Andrie"'
Publikováno v:
Genome Research. 24:2000-2010
Gene expression levels are determined by the balance between rates of mRNA transcription and decay, and genetic variation in either of these processes can result in heritable differences in transcript abundance. Although the genetics of gene expressi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38cfdf46748e015ff5f82bac83f3a693
https://doi.org/10.1101/gr.175802.114
https://doi.org/10.1101/gr.175802.114
Autor:
Choli Lee, Robin P. Smith, Rupali P Patwardhan, Mee J. Kim, Jay Shendure, Joseph B. Hiatt, Len A. Pennacchio, Daniela Witten, Gregory M. Cooper, Dalit May, Jennifer M. Andrie, Su-In Lee, Nadav Ahituv
Publikováno v:
Nature biotechnology, vol 30, iss 3
Nature biotechnology
Nature biotechnology
The functional consequences of genetic variation in mammalian regulatory elements are poorly understood. We report the in vivo dissection of three mammalian liver enhancers at single nucleotide resolution via a massively parallelized reporter assay.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0e64e7ff7d5ff3e89e311b2aeff9d36
https://doi.org/10.1038/nbt.2136
https://doi.org/10.1038/nbt.2136