Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Jennifer M Raoul"'
Publikováno v:
Canadian Journal of Gastroenterology, Vol 18, Iss 1, Pp 22-24 (2004)
Systemic sclerosis (SSc), or scleroderma, is a connective tissue disorder characterized by progressive fibrosis of the skin and internal organs. It has significance for gastroenterologists because the gastrointestinal tract is involved in 90% of SSc
Externí odkaz:
https://doaj.org/article/c14ad462dff142f68952675e92941db5
Publikováno v:
European journal of pharmacology. 662(1-3)
TNBS-induced colitis has characteristics resembling human Crohn's disease including transmural inflammation, ulceration, and fibrosis. Current treatments target acute symptoms but do not necessarily prevent fibrotic complications of the disease. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::226927afe99662a0d764cde6bdc7dfc2
https://pubmed.ncbi.nlm.nih.gov/21554874
https://pubmed.ncbi.nlm.nih.gov/21554874
Publikováno v:
Biochemical pharmacology. 74(4)
Pentoxifylline (PTX), a methylxanthine derivative, is metabolized to seven compounds in vivo, with metabolites 1 and 5 possessing biologic activity. Metabolite-1 is a chiral molecule and its S-enantiomer is selectively formed during PTX metabolism in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c059085a720a49aaaf05379aca80c535
https://pubmed.ncbi.nlm.nih.gov/17599808
https://pubmed.ncbi.nlm.nih.gov/17599808