Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Jennifer M Brelsfoard"'
Publikováno v:
PLoS ONE, Vol 11, Iss 7, p e0159442 (2016)
Millions of mild traumatic brain injuries (TBIs) occur every year in the United States, with many people subject to multiple head injuries that can lead to chronic behavioral dysfunction. We previously reported that mild TBI induced using closed head
Externí odkaz:
https://doaj.org/article/311c9b1e5f2b4686a94c9a46e094ebbb
Autor:
Sindhu K Madathil, Shaun W Carlson, Jennifer M Brelsfoard, Ping Ye, A Joseph D'Ercole, Kathryn E Saatman
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e67204 (2013)
Traumatic brain injury (TBI) survivors often suffer from long-lasting cognitive impairment that stems from hippocampal injury. Systemic administration of insulin-like growth factor-1 (IGF-1), a polypeptide growth factor known to play vital roles in n
Externí odkaz:
https://doaj.org/article/16c4ad97a8ec40e996f44a89645d510f
Autor:
Govind Warrier, Kathryn E. Saatman, Jeriel T. R. Keeney, David K. Powell, Rukhsana Sultana, Daret K. St. Clair, Xiaojia Ren, Teresa Noel, D. Allan Butterfield, Jennifer M. Brelsfoard
Publikováno v:
Oncotarget
Chemotherapy-induced cognitive impairment (CICI) is now widely recognized as a real and too common complication of cancer chemotherapy experienced by an ever-growing number of cancer survivors. Previously, we reported that doxorubicin (Dox), a protot
Autor:
Jennifer Lilley, Dianise Rodriguez Garcia, Jennifer M. Brelsfoard, Josée Guindon, Ismael Rodríguez Lugo Rodríguez, Henry L. Blanton
Publikováno v:
The FASEB Journal. 33
Autor:
Kathryn E. Saatman, Sindhu K. Madathil, Jiro Takano, Kathleen M. Schoch, Jennifer M. Brelsfoard, Heather N. Evans, Takaomi C. Saido
Publikováno v:
Experimental Neurology. 236:371-382
Traumatic brain injury (TBI) results in abrupt, initial cell damage leading to delayed neuronal death. The calcium-activated proteases, calpains, are known to contribute to this secondary neurodegenerative cascade. Although the specific inhibitor of
Autor:
Kathryn E. Saatman, Shaun W. Carlson, Jennifer M. Brelsfoard, Erica Littlejohn, Megan Pannell, Travis Stewart, Douglas A. Andres, Weikang Cai
Publikováno v:
The FASEB Journal. 29
Autor:
Shaun W. Carlson, Jennifer M. Brelsfoard, Kathryn E. Saatman, Sindhu K. Madathil, A. Joseph D'Ercole, Ping Ye
Publikováno v:
PLoS ONE
PLoS ONE, Vol 8, Iss 6, p e67204 (2013)
PLoS ONE, Vol 8, Iss 6, p e67204 (2013)
Traumatic brain injury (TBI) survivors often suffer from long-lasting cognitive impairment that stems from hippocampal injury. Systemic administration of insulin-like growth factor-1 (IGF-1), a polypeptide growth factor known to play vital roles in n
Publikováno v:
PLoS ONE, Vol 11, Iss 7, p e0159442 (2016)
PLoS ONE
PLoS ONE
Millions of mild traumatic brain injuries (TBIs) occur every year in the United States, with many people subject to multiple head injuries that can lead to chronic behavioral dysfunction. We previously reported that mild TBI induced using closed head
Autor:
Catherine E. Mannon, Carole L. Moncman, Douglas A. Andres, Weikang Cai, Kathryn E. Saatman, Shaun W. Carlson, Jennifer M. Brelsfoard
Publikováno v:
The Journal of neuroscience : the official journal of the Society for Neuroscience. 32(29)
The molecular mechanisms governing the spontaneous recovery seen following brain injury remain elusive, but recent studies indicate that injury-induced stimulation of hippocampal neurogenesis contributes to the repair process. The therapeutic potenti
Autor:
Jennifer M. Brelsfoard, Savita Sharma, Sarah Srodulski, Xinmin S imon Xie, Conrado Pascual, Linda J. Van Eldik, Adam B. Bachstetter, Florin Despa, Kathryn E. Saatman
Publikováno v:
Molecular Neurodegeneration
Background We recently found that brain tissue from patients with type-2 diabetes (T2D) and cognitive impairment contains deposits of amylin, an amyloidogenic hormone synthesized and co-secreted with insulin by pancreatic β-cells. Amylin deposition