Zobrazeno 1 - 10 of 90 pro vyhledávání: '"Jennifer M Bossert"'
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Akademický článek
Discriminative stimuli are sufficient for incubation of cocaine craving
Autor: Rajtarun Madangopal, Brendan J Tunstall, Lauren E Komer, Sophia J Weber, Jennifer K Hoots, Veronica A Lennon, Jennifer M Bossert, David H Epstein, Yavin Shaham, Bruce T Hope
Publikováno v: eLife, Vol 8 (2019)
In abstinent drug addicts, cues formerly associated with drug-taking experiences gain relapse-inducing potency (‘incubate’) over time. Animal models of incubation may help develop treatments to prevent relapse, but these models have ubiquitously
Externí odkaz: https://doaj.org/article/dd1c5cdadf0c42d6a522a5193016f968
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Role of Piriform Cortex and Its Afferent Projections in Relapse to Fentanyl Seeking after Food Choice-Induced Voluntary Abstinence
Autor: Sarah M. Claypool, David J. Reiner, Sana Behdin, Javier Orihuel, Ashley Batista, Kiera E. Caldwell, Jonathan J. Chow, Jennifer M. Bossert, F. Javier Rubio, Bruce T. Hope, Yavin Shaham
Publikováno v: The Journal of Neuroscience. 43:2597-2614
We previously demonstrated a role of piriform cortex (Pir) in relapse to fentanyl seeking after food choice-induced voluntary abstinence. Here, we used this model to further study the role of Pir and its afferent projections in fentanyl relapse. We t
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::427e41d055dac4bf5f98bbc5ba54c4f2
https://doi.org/10.1523/jneurosci.0034-23.2023
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Animal Models of Drug Relapse and Craving after Voluntary Abstinence: A Review
Autor: Jennifer M. Bossert, Yavin Shaham, Marco Venniro, Ida Fredriksson, Jonathan J Chow, David J. Reiner
Publikováno v: Pharmacological Reviews. 73:1050-1083
Relapse to drug use during abstinence is a defining feature of addiction. During the last several decades, this clinical scenario has been studied at the preclinical level using classic relapse/reinstatement models in which drug seeking is assessed a
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b40d4f5b4a3a4e09df674fd36a51a7c1
https://doi.org/10.1124/pharmrev.120.000191
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7
Inactivation of the infralimbic cortex decreases discriminative stimulus-controlled relapse to cocaine seeking in rats
Autor: Olivia R Drake, Bruce T. Hope, Jennifer M. Bossert, Leslie A. Ramsey, Veronica A Lennon, Brendan J. Tunstall, Rajtarun Madangopal, Megan B Brenner, Lauren E Komer, Sophia J Weber, Yavin Shaham
Publikováno v: Neuropsychopharmacology
Persistent susceptibility to cue-induced relapse is a cardinal feature of addiction. Discriminative stimuli (DSs) are one type of drug-associated cue that signal drug availability (DS+) or unavailability (DS−) and control drug seeking prior to rela
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::553271639e902469e3ee01f897f3b41e
https://doi.org/10.1038/s41386-021-01067-6
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8
In a Rat Model of Opioid Maintenance, the G Protein–Biased Mu Opioid Receptor Agonist TRV130 Decreases Relapse to Oxycodone Seeking and Taking and Prevents Oxycodone-Induced Brain Hypoxia
Autor: Shruthi A. Thomas, Bruce E. Blough, David Perekopskiy, David H. Epstein, Eugene A. Kiyatkin, Jennifer K. Hoots, Ida Fredriksson, Anum Afzal, Yavin Shaham, Hannah Korah, S. Stevens Negus, Jennifer M. Bossert
Publikováno v: Biological Psychiatry. 88:935-944
Background Maintenance treatment with opioid agonists (buprenorphine, methadone) is effective for opioid addiction but does not eliminate opioid use in all patients. We modeled maintenance treatment in rats that self-administered the prescription opi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ebf321f88f871cc0e5973237a7ed6e7a
https://doi.org/10.1016/j.biopsych.2020.02.014
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Effect of the dopamine stabilizer (-)-OSU6162 on potentiated incubation of opioid craving after electric barrier-induced voluntary abstinence
Autor: Yavin Shaham, Angelica Minier-Toribio, Sarah V. Applebey, Aniruddha Shekara, Ida Fredriksson, Jennifer M. Bossert
Publikováno v: Neuropsychopharmacology
In the classical incubation of drug craving rat model, drug seeking is assessed after homecage forced abstinence. However, human abstinence is often voluntary because negative consequences of drug seeking outweigh the desire for the drug. Here, we de
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec1cc1cdfb5de8f6a633a6066200c00c
https://doi.org/10.1038/s41386-020-0602-6
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10
Sex differences in the effect of chronic delivery of the buprenorphine analogue BU08028 on heroin relapse and choice in a rat model of opioid maintenance
Autor: Kenner C. Rice, Lindsay K-P Altidor, Stephen M. Husbands, Aniruddha Shekara, E. Andrew Townsend, Yavin Shaham, Jennifer M. Bossert, Ida Fredriksson, Agnieszka Sulima, Matthew L. Banks
Publikováno v: Bossert, J M, Townsend, E A, Altidor, L K P, Fredriksson, I, Shekara, A, Husbands, S, Sulima, A, Rice, K C, Banks, M L & Shaham, Y 2022, ' Sex differences in the effect of chronic delivery of the buprenorphine analogue BU08028 on heroin relapse and choice in a rat model of opioid maintenance ', British Journal of Pharmacology, vol. 179, no. 2, pp. 227-241 . https://doi.org/10.1111/bph.15679
Background and Purpose: Maintenance treatment with opioid agonists (buprenorphine, methadone) decreases opioid use and relapse. We recently modelled maintenance treatment in rats and found that chronic delivery of buprenorphine or the μ opioid recep
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2703fb0f59a43fbd4d314b0274afe26
https://pubmed.ncbi.nlm.nih.gov/34505281
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