Zobrazeno 1 - 10
of 65
pro vyhledávání: '"Jennifer M, Frost"'
Autor:
Hemanth Tummala, Amanda J Walne, Mohsin Badat, Manthan Patel, Abigail M Walne, Jenna Alnajar, Chi Ching Chow, Ibtehal Albursan, Jennifer M Frost, David Ballard, Sally Killick, Peter Szitányi, Anne M Kelly, Manoj Raghavan, Corrina Powell, Reinier Raymakers, Tony Todd, Elpis Mantadakis, Sophia Polychronopoulou, Nikolas Pontikos, Tianyi Liao, Pradeep Madapura, Upal Hossain, Tom Vulliamy, Inderjeet Dokal
Publikováno v:
EMBO Molecular Medicine, Vol 16, Iss 10, Pp 2560-2582 (2024)
Abstract Dyskeratosis congenita (DC) is a rare inherited bone marrow failure syndrome, caused by genetic mutations that principally affect telomere biology. Approximately 35% of cases remain uncharacterised at the genetic level. To explore the geneti
Externí odkaz:
https://doaj.org/article/a5c1a71362e94f24b64c6893fb53d636
Autor:
Jennifer M. Frost, Jaehoon Lee, Ping-Hung Hsieh, Samuel J. H. Lin, Yunsook Min, Matthew Bauer, Anne M. Runkel, Hyung-Taeg Cho, Tzung-Fu Hsieh, Robert L. Fischer, Yeonhee Choi
Publikováno v:
BMC Plant Biology, Vol 23, Iss 1, Pp 1-15 (2023)
Abstract Background H2A.X is an H2A variant histone in eukaryotes, unique for its ability to respond to DNA damage, initiating the DNA repair pathway. H2A.X replacement within the histone octamer is mediated by the FAcilitates Chromatin Transactions
Externí odkaz:
https://doaj.org/article/a6237e31bba14b75a5dd00fcdf5e8d69
Autor:
Kevin C. L. Cheng, Jennifer M. Frost, Francisco J. Sánchez-Luque, Marta García-Canãdas, Darren Taylor, Wan R. Yang, Branavy Irayanar, Swetha Sampath, Hemalvi Patani, Karl Agger, Kristian Helin, Gabriella Ficz, Kathleen H. Burns, Adam Ewing, José L. García-Pérez, Miguel R. Branco
Publikováno v:
Epigenetics & Chromatin, Vol 16, Iss 1, Pp 1-16 (2023)
Abstract Background Vitamin C (vitC) enhances the activity of 2-oxoglutarate-dependent dioxygenases, including TET enzymes, which catalyse DNA demethylation, and Jumonji-domain histone demethylases. The epigenetic remodelling promoted by vitC improve
Externí odkaz:
https://doaj.org/article/f795feb9ee214159af694527040dae95
Autor:
Chirag Patel, Meng Sun, Yue Liu, Jonathan Powell, Kyle Halliwill, Jennifer M Frost, Robert T Manguso, Kathleen B Yates, Hakimeh Ebrahimi-Nik, Christina K Baumgartner, Keith M Hamel, Kira Olander, Kathleen A McGuire, Audrey J Muscato, Kelly Klinge, Joseph Klahn, Jacqueline Aguado, Payal Tiwari, Kayla J Colvin, Marcia N Paddock, Philip R Kym, Omar Avila-Monge, Alexander Schutte
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/91cbd5f2b1c44b56be7bd4787add03a6
Autor:
Wei Qiu, Qi Sun, Yi Yang, Chirag Patel, Meng Sun, Yue Liu, Kyle Halliwill, Sarah Kim, Rebecca Mathew, Jennifer M Frost, Jennifer A Roth, Domenick Kennedy, Robert T Manguso, Kathleen B Yates, Hakimeh Ebrahimi-Nik, Christina K Baumgartner, Arvin Iracheta-Vellve, Keith M Hamel, Kira Olander, Thomas GR Davis, Kathleen A McGuire, Geoff T Halvorsen, Omar I Avila, Ashwin V Kammula, Audrey J Muscato, Prasanthi Geda, Kelly Klinge, Zhaoming Xiong, Ryan Duggan, Liang Mu, Mitchell D Yeary, James C Patti, Tyler M Balon, Carey Backus, Angeline Chen, Kenton Longenecker, Joseph Klahn, Cara Hrusch, Navasona Krishnan, Charles W Hutchins, Jacqueline Aguado, Marinka Bulic, Payal Tiwari, Kayla J Colvin, Cun Lan Chuong, Ian C Kohnle, Matthew G Rees, Andrew Boghossian, Melissa Ronan, Meng-Ju Wu, Debattama R Sen, Gabriel K Griffin, Nabeel El-Bardeesy, Patricia Trusk, Joshua H Decker, Stacey Fossey, Marcia N Paddock, Elliot P Farney, Clay Beauregard, Philip R Kym
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 2 (2023)
Externí odkaz:
https://doaj.org/article/11356ff1bf1f4b63ab1324cafa253315
Autor:
Jaehoon Lee, Seunga Lee, Kyunghyuk Park, Sang-Yoon Shin, Jennifer M. Frost, Ping-Hung Hsieh, Chanseok Shin, Robert L. Fischer, Tzung-Fu Hsieh, Yeonhee Choi
Publikováno v:
Frontiers in Plant Science, Vol 14 (2023)
CHH methylation (mCHH) increases gradually during embryogenesis across dicotyledonous plants, indicating conserved mechanisms of targeting and conferral. Although it is suggested that methylation increase during embryogenesis enhances transposable el
Externí odkaz:
https://doaj.org/article/93dd3f5846c444129b6bcb663d2e6289
Autor:
Brogan Ashley, Claire Simner, Antigoni Manousopoulou, Carl Jenkinson, Felicity Hey, Jennifer M Frost, Faisal I Rezwan, Cory H White, Emma M Lofthouse, Emily Hyde, Laura DF Cooke, Sheila Barton, Pamela Mahon, Elizabeth M Curtis, Rebecca J Moon, Sarah R Crozier, Hazel M Inskip, Keith M Godfrey, John W Holloway, Cyrus Cooper, Kerry S Jones, Rohan M Lewis, Martin Hewison, Spiros DD Garbis, Miguel R Branco, Nicholas C Harvey, Jane K Cleal
Publikováno v:
eLife, Vol 11 (2022)
Pregnancy 25-hydroxyvitamin D [25(OH)D] concentrations are associated with maternal and fetal health outcomes. Using physiological human placental perfusion and villous explants, we investigate the role of the placenta in regulating the relationships
Externí odkaz:
https://doaj.org/article/1a91c1a9eb944011801afd9ea0ec61b3
Autor:
Jennifer M. Frost, Samuele M. Amante, Hiroaki Okae, Eleri M. Jones, Brogan Ashley, Rohan M. Lewis, Jane K. Cleal, Matthew P. Caley, Takahiro Arima, Tania Maffucci, Miguel R. Branco
Publikováno v:
Nature Structural & Molecular Biology. 30:527-538
The placenta is a fast-evolving organ with large morphological and histological differences across eutherians, but the genetic changes driving placental evolution have not been fully elucidated. Transposable elements, through their capacity to quickl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb795c7139991854881f11795581ec0d
https://doi.org/10.1038/s41594-023-00960-6
https://doi.org/10.1038/s41594-023-00960-6
Autor:
Yao Liang Wong, Lauren LeBon, Ana M Basso, Kathy L Kohlhaas, Arthur L Nikkel, Holly M Robb, Diana L Donnelly-Roberts, Janani Prakash, Andrew M Swensen, Nimrod D Rubinstein, Swathi Krishnan, Fiona E McAllister, Nicole V Haste, Jonathon J O'Brien, Margaret Roy, Andrea Ireland, Jennifer M Frost, Lei Shi, Stephan Riedmaier, Kathleen Martin, Michael J Dart, Carmela Sidrauski
Publikováno v:
eLife, Vol 8 (2019)
The integrated stress response (ISR) attenuates the rate of protein synthesis while inducing expression of stress proteins in cells. Various insults activate kinases that phosphorylate the GTPase eIF2 leading to inhibition of its exchange factor eIF2
Externí odkaz:
https://doaj.org/article/7ff3f238f99040afb97c2dc3b9419d6e
Autor:
Jennifer M. Frost, Jaehoon Lee, Ping-Hung Hsieh, Samuel J. H. Lin, Yunsook Min, Matthew Bauer, Anne M. Runkel, Hyung-Taeg Cho, Tzung-Fu Hsieh, Yeonhee Choi, Robert L. Fischer
H2A.Xis an H2A variant histone in eukaryotes, unique for its ability to respond to DNA damage, initiating the DNA repair pathway.H2A.Xreplacement within the histone octamer is mediated by the FAcilitates Chromatin Transactions (FACT) complex, a key c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1fd134469e661f9d5e715849327e64f9
https://doi.org/10.1101/2023.01.08.523178
https://doi.org/10.1101/2023.01.08.523178
