Zobrazeno 1 - 10
of 126
pro vyhledávání: '"Jennifer L. Wilkinson-Berka"'
Autor:
Matthew Snelson, Devy Deliyanti, Sih Min Tan, Anna M. Drake, Cassandra de Pasquale, Vinod Kumar, Trent M. Woodruff, Jennifer L. Wilkinson-Berka, Melinda T. Coughlan
Publikováno v:
Nutrition & Diabetes, Vol 14, Iss 1, Pp 1-9 (2024)
Abstract Background Dietary-resistant starch is emerging as a potential therapeutic tool to limit the negative effects of diabetes on the kidneys. However, its metabolic and immunomodulatory effects have not yet been fully elucidated. Methods Six-wee
Externí odkaz:
https://doaj.org/article/cd9801adaeb54c4aa4d47220bd44381f
Autor:
Devy Deliyanti, Varaporn Suphapimol, Phoebe Ang, Xiuying Tang, Abhirup Jayasimhan, Jennifer L. Wilkinson-Berka
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 21, p 15680 (2023)
Retinal inflammation is a central feature of ocular neovascular diseases such as diabetic retinopathy and retinopathy of prematurity, but the contribution of neutrophils to this process is not fully understood. We studied oxygen-induced retinopathy (
Externí odkaz:
https://doaj.org/article/88843de44a5e490b9a9d798a4625a338
Autor:
Jack R. Jerome, Devy Deliyanti, Varaporn Suphapimol, Peter Kolkhof, Jennifer L. Wilkinson-Berka
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 3, p 2334 (2023)
Vision loss in diabetic retinopathy features damage to the blood–retinal barrier and neovascularization, with hypertension and the renin–angiotensin system (RAS) having causal roles. We evaluated if finerenone, a non-steroidal mineralocorticoid r
Externí odkaz:
https://doaj.org/article/acca4343828a4561855ca08374ba017a
Autor:
Jae Young Lee, Min Joung Kim, Devy Deliyanti, Michael F. Azari, Fernando Rossello, Adam Costin, Georg Ramm, Edouard G. Stanley, Andrew G. Elefanty, Jennifer L. Wilkinson-Berka, Steven Petratos
Publikováno v:
EBioMedicine, Vol 25, Iss C, Pp 122-135 (2017)
Cell membrane thyroid hormone (TH) transport can be facilitated by the monocarboxylate transporter 8 (MCT8), encoded by the solute carrier family 16 member 2 (SLC16A2) gene. Human mutations of the gene, SLC16A2, result in the X-linked-inherited psych
Externí odkaz:
https://doaj.org/article/882af120b3544086aabd413230c8b89d
Autor:
Devy Deliyanti, Dean M. Talia, Tong Zhu, Mhairi J. Maxwell, Alex Agrotis, Jack R. Jerome, Emily M. Hargreaves, Steven Gerondakis, Margaret L. Hibbs, Fabienne Mackay, Jennifer L. Wilkinson-Berka
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
The local immune responses in the eye are attenuated to preserve sight. Surprisingly, Deliyanti et al. show that regulatory T cells (Tregs) take an active role in protecting the eye from neovascularization in oxygen-induced retinopathy, and that inte
Externí odkaz:
https://doaj.org/article/50f3675a81e5466f9c5075205f5d2ecb
Publikováno v:
The Scientific World Journal, Vol 8, Pp 98-120 (2008)
Retinopathy is the most feared complication of diabetes, compromising quality of life in most sufferers. Almost all patients with type 1 diabetes will develop retinopathy over a 15- to 20-year period, and approximately 20–30% will advance to the bl
Externí odkaz:
https://doaj.org/article/f2dc911fc64e4b438ded6094bf5bd048
Autor:
Devy Deliyanti, William A. Figgett, Thomas Gebhardt, Joseph A. Trapani, Fabienne Mackay, Jennifer L. Wilkinson-Berka
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 43:522-536
Background: CD4 + (cluster of differentation) and CD8 + T cells are increased in the ocular fluids of patients with neovascular retinopathy, yet their role in the disease process is unknown. Methods: We describe how CD8 + T cells migrate into the ret
Autor:
Margaret L. Hibbs, Peter van Wijngaarden, Chad Johnson, Dean M Talia, Evelyn Tsantikos, Timothy A. Gottschalk, Jennifer L. Wilkinson-Berka, Lakshanie C Wickramasinghe, Maverick Lau, Devy Deliyanti
Publikováno v:
The American Journal of Pathology. 190:1801-1812
Bronchopulmonary dysplasia (BPD) and retinopathy of prematurity (ROP) are two debilitating disorders that develop in preterm infants exposed to supplemental oxygen to prevent respiratory failure. Both can lead to lifelong disabilities, such as chroni
Autor:
Karin Jandeleit-Dahm, Rhian M. Touyz, Jay C. Jha, Chris R. J. Kennedy, Devy Deliyanti, Jennifer L. Wilkinson-Berka, Mark E. Cooper, Saeed F. Alrashdi
Publikováno v:
Hypertension. 75:1091-1101
Hypertension is a risk factor for the vascular permeability and neovascularization that threatens vision in diabetic retinopathy. Excess reactive oxygen species derived from the Nox (NADPH oxidase) isoforms, Nox1 and Nox4, contributes to vasculopathy
Autor:
Erin N.S. McGowan, Osanna Wong, Eleanor Jones, Julie Nguyen, Janet Wee, Maria C. Demaria, Devy Deliyanti, Chad J. Johnson, Michael J. Hickey, Malcolm J. McConville, Jennifer L. Wilkinson-Berka, Mark D. Wright, Katrina J. Binger
Publikováno v:
iScience. 25(7)
Phagocytes migrate into tissues to combat infection and maintain tissue homeostasis. As dysregulated phagocyte migration and function can lead to inflammation or susceptibility to infection, identifying molecules that control these processes is criti