Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Jennifer L. Wacker"'
Publikováno v:
Biochemical and Biophysical Research Communications. 393:603-608
Precise spatial and temporal expression of the recently identified G-protein coupled receptor GPR54 is critical for proper reproductive function and metastasis suppression. However, regulatory factors that control GPR54 expression remain unknown. Thu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07a1822335a487592b0185b310aee383
https://doi.org/10.1016/j.bbrc.2010.02.026
https://doi.org/10.1016/j.bbrc.2010.02.026
Autor:
Soyon Hong, Robert Schwarcz, Jennifer L. Wacker, Li-Chun L. Tsai, Flaviano Giorgini, Christine S. Cheah, Daniel Zwilling, Paolo Guidetti, Paul J. Muchowski, Wanda Kwan, Thomas Möller
Publikováno v:
Journal of Biological Chemistry. 283:7390-7400
The kynurenine pathway of tryptophan degradation is hypothesized to play an important role in Huntington disease, a neurodegenerative disorder caused by a polyglutamine expansion in the protein huntingtin. Neurotoxic metabolites of the kynurenine pat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::257f7c48578a37f85945fc8f7d50418c
https://doi.org/10.1074/jbc.m708192200
https://doi.org/10.1074/jbc.m708192200
Autor:
Dorathy-Ann Harris, Nathan D. Camp, Nephi Stella, Jennifer L. Wacker-Mhyre, Kyung Soon Lee, Alejandro Wolf-Yadlin, Timothy S. Kountz, Ji Min Park, Allison E. Cherry, Aaron Stewart, Marianne Estrada, Chris Hague
Publikováno v:
Pharmacological research. 105
G protein-coupled receptors (GPCRs) are essential membrane proteins that facilitate cell-to-cell communication and co-ordinate physiological processes. At least 30 human GPCRs contain a Type I PSD-95/DLG/Zo-1 (PDZ) ligand in their distal C-terminal d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c97ec4008440d6103ceda4b8e1d84d69
https://pubmed.ncbi.nlm.nih.gov/26773201
https://pubmed.ncbi.nlm.nih.gov/26773201
Autor:
Paul J. Muchowski, Jennifer L. Wacker
Publikováno v:
Nature Reviews Neuroscience. 6:11-22
Many neurodegenerative disorders are characterized by conformational changes in proteins that result in misfolding, aggregation and intra- or extra-neuronal accumulation of amyloid fibrils. Molecular chaperones provide a first line of defence against
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5143966e0cc899623fa1315e4ce89d84
https://doi.org/10.1038/nrn1587
https://doi.org/10.1038/nrn1587
Autor:
Marvin E. Adams, Jennifer L. Wacker, Mia C. DeFino, Chris Hague, John S. Lyssand, Richard G. Gardner, Xiao-bo Tang
Publikováno v:
The FASEB Journal. 24
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::daabc60183e5b1fd58e4885186f34745
https://doi.org/10.1096/fasebj.24.1_supplement.771.5
https://doi.org/10.1096/fasebj.24.1_supplement.771.5
Autor:
Flaviano Giorgini, Rebecca Aron, Shao-Yi Huang, Andrew D. Steele, Gregor P. Lotz, Eliezer Masliah, Jennifer L. Wacker, Paul J. Muchowski, Susan Lindquist, Erik D. Roberson, QuangVu Nguyen
Publikováno v:
Paul Muchowski
Endogenous protein quality control machinery has long been suspected of influencing the onset and progression of neurodegenerative diseases characterized by accumulation of misfolded proteins. Huntington's disease (HD) is a fatal neurodegenerative di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d615fc830ea0be78ef569739438b391
https://orcid.org/0000-0003-1307-882X
https://orcid.org/0000-0003-1307-882X
Autor:
Nephi Stella, Ning Zheng, Jennifer L. Wacker, John S. Lyssand, Chris Hague, Xiao-bo Tang, Xu Tan, Mia C. DeFino
Publikováno v:
The FASEB Journal. 23
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4d524cd7da7497922fa8bba84e84b3cf
https://doi.org/10.1096/fasebj.23.1_supplement.943.5
https://doi.org/10.1096/fasebj.23.1_supplement.943.5
Publikováno v:
The FASEB Journal. 23
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d84665593273cca5b5476df12a460dbe
https://doi.org/10.1096/fasebj.23.1_supplement.945.8
https://doi.org/10.1096/fasebj.23.1_supplement.945.8
Autor:
David B. Feller, Mia C. DeFino, John S. Lyssand, Xiao Bo Tang, Yuree Namkung, Xu Tan, Jennifer L. Wacker, Andrew J. Mhyre, Jill B. Jensen, Chris Hague
Publikováno v:
The Journal of biological chemistry. 283(45)
The G-protein-coupled receptor (GPCR) GPR54 is essential for the development and maintenance of reproductive function in mammals. A point mutation (L148S) in the second intracellular loop (IL2) of GPR54 causes idiopathic hypogonadotropic hypogonadism
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7db269f1cde314fe873befe7828aa235
https://pubmed.ncbi.nlm.nih.gov/18772143
https://pubmed.ncbi.nlm.nih.gov/18772143
Autor:
Xiao Bo Tang, Jennifer L. Wacker, John S. Lyssand, Mia C. DeFino, Chris Hague, David Feller, Marvin E. Adams, Angie L. Hertz
Publikováno v:
The Journal of biological chemistry. 283(27)
Hypertension is a cardiovascular disease associated with increased plasma catecholamines, overactivation of the sympathetic nervous system, and increased vascular tone and total peripheral resistance. A key regulator of sympathetic nervous system fun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72b2b42e6a0be3576a133bfb46d5808f
https://pubmed.ncbi.nlm.nih.gov/18468998
https://pubmed.ncbi.nlm.nih.gov/18468998