Zobrazeno 1 - 10
of 77
pro vyhledávání: '"Jennifer L. Strande"'
Cardioprotective effect of nicorandil on isoproterenol induced cardiomyopathy in the Mdx mouse model
Autor:
Rachel T. Sullivan, Ngoc T. Lam, Margaret Haberman, Margaret J. Beatka, Muhammad Z. Afzal, Michael W. Lawlor, Jennifer L. Strande
Publikováno v:
BMC Cardiovascular Disorders, Vol 21, Iss 1, Pp 1-12 (2021)
Abstract Background Duchenne muscular dystrophy (DMD) associated cardiomyopathy is a major cause of morbidity and mortality. In an in vitro DMD cardiomyocyte model, nicorandil reversed stress-induced cell injury through multiple pathways implicated i
Externí odkaz:
https://doaj.org/article/27452b7bb7ef412c87f7f413898a5d0f
Autor:
Melanie Gartz PhD, MS, MHS, Margaret Haberman BS, Mariah J. Prom BS, Margaret J. Beatka BS, Jennifer L. Strande MD, PhD, Michael W. Lawlor MD, PhD
Publikováno v:
Journal of Cardiovascular Pharmacology and Therapeutics, Vol 27 (2022)
Background: Duchenne muscular dystrophy (DMD) is a neuromuscular disease caused by dystrophin gene mutations affecting striated muscle. Due to advances in skeletal muscle treatment, cardiomyopathy has emerged as a leading cause of death. Previously,
Externí odkaz:
https://doaj.org/article/df4e0a322cc3431fa3169f7e1a3396ca
Autor:
Yvonne E. Kaptein, Ilya Karagodin, Hongquan Zuo, Yu Lu, Jun Zhang, John S. Kaptein, Jennifer L. Strande
Publikováno v:
BMC Cardiovascular Disorders, Vol 20, Iss 1, Pp 1-15 (2020)
Abstract Background Subclinical diastolic dysfunction is a precursor for developing heart failure with preserved ejection fraction (HFpEF); yet not all patients progress to HFpEF. Our objective was to evaluate clinical and echocardiographic variables
Externí odkaz:
https://doaj.org/article/8833054e9c1d44f881e86770694614ee
Publikováno v:
JACC: Case Reports, Vol 1, Iss 2, Pp 213-217 (2019)
A 56-year-old man with multiple cardiac manifestations of type 1 myotonic dystrophy, including severe, nonischemic cardiomyopathy, presented in refractory cardiogenic shock requiring inotropic therapy. Given his wishes to die without having any intra
Externí odkaz:
https://doaj.org/article/2562671b9ed649d9aeb2236ac0b40995
Publikováno v:
Disease Models & Mechanisms, Vol 13, Iss 11 (2020)
Cardiomyopathy is a leading cause of early mortality in Duchenne muscular dystrophy (DMD). There is a need to gain a better understanding of the molecular pathogenesis for the development effective therapies. Exosomes (exo) are secreted vesicles and
Externí odkaz:
https://doaj.org/article/405ff892a99241988fcfad6b9d67a997
Autor:
Carmen Bergom, Jason Rubenstein, J. Frank Wilson, Aimee Welsh, El-Sayed H. Ibrahim, Phillip Prior, Aronne M. Schottstaedt, Daniel Eastwood, Mei-Jie Zhang, Adam Currey, Lindsay Puckett, Jennifer L. Strande, Julie A. Bradley, Julia White
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
Purpose/ObjectivesNode-positive breast cancer patients often receive chemotherapy and regional nodal irradiation. The cardiotoxic effects of these treatments, however, may offset some of the survival benefit. Cardiac magnetic resonance (CMR) is an em
Externí odkaz:
https://doaj.org/article/d6a2002a8e554b7e92ad3091939b5b10
Autor:
Karthikeyan Thirugnanam, Stephanie M. Cossette, Qiulun Lu, Shreya R. Chowdhury, Leanne M. Harmann, Ankan Gupta, Andrew D. Spearman, Dmitry L. Sonin, Michelle Bordas, Suresh N. Kumar, Amy Y. Pan, Pippa M. Simpson, Jennifer L. Strande, Erin Bishop, Ming‐Hui Zou, Ramani Ramchandran
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 8, Iss 22 (2019)
Background The SNRK (sucrose‐nonfermenting–related kinase) enzyme is critical for cardiac function. However, the underlying cause for heart failure observed in Snrk cardiac conditional knockout mouse is unknown. Methods and Results Previously, 6
Externí odkaz:
https://doaj.org/article/9425db3854dc4a599dccceb7725c602a
Autor:
Melanie Gartz, Jennifer L. Strande
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 7, Iss 11 (2018)
Externí odkaz:
https://doaj.org/article/24de33fea29345149c2763bc89d6719d
Autor:
Rakesh H. Basavalingappa, Chandirasegaran Massilamany, Bharathi Krishnan, Arunakumar Gangaplara, Rajkumar A. Rajasekaran, Muhammad Z. Afzal, Jean-Jack Riethoven, Jennifer L. Strande, David Steffen, Jay Reddy
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
Myocarditis/dilated cardiomyopathy (DCM) patients can develop autoantibodies to various cardiac antigens and one major antigen is β1-adrenergic receptor (β1AR). Previous reports indicate that animals immunized with a β1AR fragment encompassing, 19
Externí odkaz:
https://doaj.org/article/892c4a515e254cef9c166d5606401b77
Autor:
Xuan Guan, David L. Mack, Claudia M. Moreno, Jennifer L. Strande, Julie Mathieu, Yingai Shi, Chad D. Markert, Zejing Wang, Guihua Liu, Michael W. Lawlor, Emily C. Moorefield, Tara N. Jones, James A. Fugate, Mark E. Furth, Charles E. Murry, Hannele Ruohola-Baker, Yuanyuan Zhang, Luis F. Santana, Martin K. Childers
Publikováno v:
Stem Cell Research, Vol 12, Iss 2, Pp 467-480 (2014)
The ability to extract somatic cells from a patient and reprogram them to pluripotency opens up new possibilities for personalized medicine. Induced pluripotent stem cells (iPSCs) have been employed to generate beating cardiomyocytes from a patient's
Externí odkaz:
https://doaj.org/article/30584e3c6056463b9e8661b023c8cc52