Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Jennifer L. Stockdill"'
Publikováno v:
ACS Central Science, Vol 9, Iss 4, Pp 590-592 (2023)
Externí odkaz:
https://doaj.org/article/452f541a9c7b42c9a0c1e66d47df809a
Autor:
Arthur Zastepa, Judy A. Westrick, Anqi Liang, Johnna A. Birbeck, Elliot Furr, L. Cynthia Watson, Jennifer L. Stockdill, Boddu S. Ramakrishna, Sophie Crevecoeur
Publikováno v:
Journal of Great Lakes Research. 49:134-146
Autor:
Naresh M. Venneti, Ganesh Samala, Rana M. I. Morsy, Lawrence G. Mendoza, Albert Isidro-Llobet, Janine K. Tom, Subha Mukherjee, Michael E. Kopach, Jennifer L. Stockdill
Publikováno v:
Journal of the American Chemical Society. 145:1053-1061
Peptides are steadily gaining importance as pharmaceutical targets, and efficient, green methods for their preparation are critically needed. A key deficiency in the synthetic toolbox is the lack of an industrially viable peptide desulfurization meth
Publikováno v:
Org Biomol Chem
C-Terminally modified peptides are important for the development and delivery of peptide-based pharmaceuticals because they impact peptide activity, stability, hydrophobicity, and membrane permeability. Additionally, the vulnerability of C-terminal e
Publikováno v:
Chemical Science. 10:10475-10480
Studies of S-linked glycoconjugates have attracted growing interest because of their enhanced chemical stability and enzymatic resistance over O-glycoside counterparts. We here report a facile approach to access α-1,2-cis-S-linked glycosides using t
Publikováno v:
Tetrahedron Letters. 59:3903-3906
In this manuscript, we establish the susceptibility of the N-methyldiaminobenzoyl linker to undergo undesired acylation during standard peptide capping with acetic anhydride. Successive capping treatments led to problematic levels of linker incapacit
Autor:
Hansamali S. Sirinimal, H. Bernhard Schlegel, Gregory J. Rosenhauer, Heng Chen, Ganesh Samala, Sebastien P. Hebert, Jennifer L. Stockdill
Publikováno v:
Organic Letters. 20:6340-6344
5- exo, 5- exo Cyclizations of conformationally unbiased propargylic aminyl radicals proceed with excellent yield, chemoselectivity, and diastereoselectivity under tin-free reductive cyclization conditions, regardless of the electronic environments a
Autor:
Alberto M. Lopez, Ahmad A. Ibrahim, Gregory J. Rosenhauer, Hansamali S. Sirinimal, Jennifer L. Stockdill
Publikováno v:
Organic Letters. 20:2216-2219
A tin-free strategy for the successful cyclization of a variety of internal alkyne-containing N-chloroamine precursors to the ABC core via cyclization of a neutral aminyl radical is established. Deuterium labeling experiments confirm that the solvent
Autor:
John A. Brailsford, Jennifer L. Stockdill, Eric V. Johnston, Abram J. Axelrod, Paul A. Vadola, Samuel J. Danishefsky, Michael T. Peterson
Publikováno v:
Tetrahedron. 74:1951-1956
The β-subunit of human thyroid stimulating hormone (hTSH) has been synthesized as a single glycoform bearing a chitobiose disaccharide at the native glycosylation site. Key to the successful completion of this synthesis was the introduction of an ar
Publikováno v:
The Journal of Organic Chemistry. 83:1797-1803
Sequence diversification at the C terminus is traditionally limited by significant epimerization of the C-terminal residue during its activation toward nucleophilic attack, thus mandating repetition of the peptide synthesis for each targeted variatio