Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Jennifer L. Stamos"'
Publikováno v:
The Journal of Biological Chemistry
Reverse transcriptases (RTs) can template switch during cDNA synthesis, enabling them to join discontinuous nucleic acid sequences. Template switching plays crucial roles in retroviral replication and recombination, is used for adapter addition in RN
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b458fcf4b0b09c19a9203a6de206a868
https://doi.org/10.1101/2021.05.13.443781
https://doi.org/10.1101/2021.05.13.443781
Publikováno v:
eLife, Vol 3 (2014)
Glycogen synthase kinase-3 (GSK-3) is a key regulator of many cellular signaling pathways. Unlike most kinases, GSK-3 is controlled by inhibition rather than by specific activation. In the insulin and several other signaling pathways, phosphorylation
Externí odkaz:
https://doaj.org/article/7c15a261e8bd48adb929dd7023bf8741
Autor:
Shunfu Piao, Sun-Hye Lee, Hyunjoon Kim, Soohwan Yum, Jennifer L Stamos, Yongbin Xu, Su-Jin Lee, Jaewon Lee, Sangtaek Oh, Jin-Kwan Han, Bum-Joon Park, William I Weis, Nam-Chul Ha
Publikováno v:
PLoS ONE, Vol 3, Iss 12, p e4046 (2008)
Wnt/beta-catenin signaling plays a central role in development and is also involved in a diverse array of diseases. Binding of Wnts to the coreceptors Frizzled and LRP6/5 leads to phosphorylation of PPPSPxS motifs in the LRP6/5 intracellular region a
Externí odkaz:
https://doaj.org/article/9bda2dacc3e34ccaac420ebedfb50da3
Autor:
Yidan Qin, Seung K. Park, Jennifer L. Stamos, Jacob K. Grohman, Jun Yao, Georg Mohr, Sean Yoon-Seo Kang, Alan M. Lambowitz
Publikováno v:
Journal of molecular biology. 430(17)
The thermostable Geobacillus stearothermophilus GsI-IIC intron is among the few bacterial group II introns found to proliferate to high copy number in its host genome. Here, we developed a bacterial genetic assay for retrohoming and biochemical assay
Bacterial group II intron reverse transcriptases (RTs) function in both intron mobility and RNA splicing and are evolutionary predecessors of retrotransposon, telomerase, and retroviral RTs as well as the spliceosomal protein Prp8 in eukaryotes. Here
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c730bc5acbdcdad0486fe0c5e9e01ed6
https://europepmc.org/articles/PMC5728383/
https://europepmc.org/articles/PMC5728383/
Publikováno v:
Molecular Cell. 15(4):511-521
The transcriptional coactivator beta-catenin mediates Wnt growth factor signaling. In the absence of a Wnt signal, casein kinase 1 (CK1) and glycogen synthase kinase-3beta (GSK-3beta) phosphorylate cytosolic beta-catenin, thereby flagging it for reco
Publikováno v:
eLife, Vol 3 (2014)
eLife
eLife
Glycogen synthase kinase-3 (GSK-3) is a key regulator of many cellular signaling pathways. Unlike most kinases, GSK-3 is controlled by inhibition rather than by specific activation. In the insulin and several other signaling pathways, phosphorylation
Autor:
William I. Weis, Sun-Hye Lee, Hyunjoon Kim, Nam-Chul Ha, Jin-Kwan Han, Sangtaek Oh, Soohwan Yum, Bum-Joon Park, Jennifer L. Stamos, Su-Jin Lee, Yongbin Xu, Jaewon Lee, Shunfu Piao
Publikováno v:
PLoS ONE
PLoS ONE, Vol 3, Iss 12, p e4046 (2008)
PLoS ONE, Vol 3, Iss 12, p e4046 (2008)
Wnt/beta-catenin signaling plays a central role in development and is also involved in a diverse array of diseases. Binding of Wnts to the coreceptors Frizzled and LRP6/5 leads to phosphorylation of PPPSPxS motifs in the LRP6/5 intracellular region a
Autor:
William I. Weis, Jennifer L. Stamos
Publikováno v:
Cold Spring Harbor Perspectives in Biology. 5:a007898-a007898
The Wnt/β-catenin pathway is highly regulated to insure the correct temporal and spatial activation of its target genes. In the absence of a Wnt stimulus, the transcriptional coactivator β-catenin is degraded by a multiprotein “destruction comple