Zobrazeno 1 - 10
of 107
pro vyhledávání: '"Jennifer L. Spratlin"'
Autor:
Carissa Beaulieu, Arthur Lui, Dimas Yusuf, Zainab Abdelaziz, Brock Randolph, Eugene Batuyong, Sunita Ghosh, Oliver F. Bathe, Vincent Tam, Jennifer L. Spratlin
Publikováno v:
Current Oncology, Vol 28, Iss 1, Pp 417-427 (2021)
Background: Biliary tract cancers (BTC) are uncommon malignancies and are underrepresented in the literature. Methods: We performed a retrospective population-based review of adult patients with biopsy-confirmed BTC in Alberta from 2000 to 2015. Demo
Externí odkaz:
https://doaj.org/article/0e6e1a15eea34548961566751d9d5b63
Autor:
Selina K. Wong, Quincy S.C. Chu, Jennifer L. Spratlin, Randeep Sangha, Alexander J.B. McEwan, Donald W. Morrish, Diane Arndt, Gwen Sergenson, Adriaan Cleton, Funan Huang, Michael B. Sawyer
Publikováno v:
Case Reports in Oncology, Vol 12, Iss 3, Pp 791-795 (2019)
Thyroid cancer is the most common type of endocrine malignancy. Cornerstones of thyroid cancer treatment include surgery, radioactive iodine ablation, and thyroid stimulating hormone suppression. The National Comprehensive Cancer Network guidelines r
Externí odkaz:
https://doaj.org/article/17f84ca3eeef446c9c88b10e69478f3b
Autor:
Karen E. Mulder, Jennifer L. Spratlin
Publikováno v:
International Journal of Molecular Sciences, Vol 12, Iss 9, Pp 5895-5907 (2011)
The incidence and mortality of pancreas cancer converge. There has been little advancement in the treatment of pancreas cancer since the acceptance of gemcitabine as the standard therapy. Unfortunately, the efficacy of gemcitabine is dismal. While th
Externí odkaz:
https://doaj.org/article/dd5772c49a604ce7907864a14ed80860
Autor:
Michelle Scurr, George Demetri, Stan B. Kaye, S. Gail Eckhardt, Andrew Stephens, Katie Brock, Richard Gedrich, Ramesh Boinpally, Srinivasu Poondru, Jon Chick, Martin O. Leach, Nandita M. Desouza, James Spicer, Rohit Lal, Jennifer L. Spratlin, Stephen J. Gwyther, Natalie J. Serkova, Suzanne George, D. Ross Camidge, Hendrik-Tobias Arkenau, Timothy A. Yap
PDF file - 41K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b799e849ebbe5a00814a032f34a1638
https://doi.org/10.1158/1078-0432.22449198
https://doi.org/10.1158/1078-0432.22449198
Autor:
Michelle Scurr, George Demetri, Stan B. Kaye, S. Gail Eckhardt, Andrew Stephens, Katie Brock, Richard Gedrich, Ramesh Boinpally, Srinivasu Poondru, Jon Chick, Martin O. Leach, Nandita M. Desouza, James Spicer, Rohit Lal, Jennifer L. Spratlin, Stephen J. Gwyther, Natalie J. Serkova, Suzanne George, D. Ross Camidge, Hendrik-Tobias Arkenau, Timothy A. Yap
PDF file - 86K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::595520b703fab59320f3f2d449b22409
https://doi.org/10.1158/1078-0432.22449195
https://doi.org/10.1158/1078-0432.22449195
Autor:
Michelle Scurr, George Demetri, Stan B. Kaye, S. Gail Eckhardt, Andrew Stephens, Katie Brock, Richard Gedrich, Ramesh Boinpally, Srinivasu Poondru, Jon Chick, Martin O. Leach, Nandita M. Desouza, James Spicer, Rohit Lal, Jennifer L. Spratlin, Stephen J. Gwyther, Natalie J. Serkova, Suzanne George, D. Ross Camidge, Hendrik-Tobias Arkenau, Timothy A. Yap
PDF file - 39K, Association of sVEGFR2 changes and steady state OSI-930 levels at the end of the first 21-day dosing cycle in the 500mg BID expansion cohort
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67d5f344fd13905f7c692557f8ce024a
https://doi.org/10.1158/1078-0432.22449204.v1
https://doi.org/10.1158/1078-0432.22449204.v1
Autor:
Michelle Scurr, George Demetri, Stan B. Kaye, S. Gail Eckhardt, Andrew Stephens, Katie Brock, Richard Gedrich, Ramesh Boinpally, Srinivasu Poondru, Jon Chick, Martin O. Leach, Nandita M. Desouza, James Spicer, Rohit Lal, Jennifer L. Spratlin, Stephen J. Gwyther, Natalie J. Serkova, Suzanne George, D. Ross Camidge, Hendrik-Tobias Arkenau, Timothy A. Yap
PDF file - 47K, Association of sVEGR2 changes at the end of the first dosing cycle and patient response in the 500mg BID expansion cohort
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05219e69e5b585c5b84a5a91ca199a34
https://doi.org/10.1158/1078-0432.22449201.v1
https://doi.org/10.1158/1078-0432.22449201.v1
Autor:
Michelle Scurr, George Demetri, Stan B. Kaye, S. Gail Eckhardt, Andrew Stephens, Katie Brock, Richard Gedrich, Ramesh Boinpally, Srinivasu Poondru, Jon Chick, Martin O. Leach, Nandita M. Desouza, James Spicer, Rohit Lal, Jennifer L. Spratlin, Stephen J. Gwyther, Natalie J. Serkova, Suzanne George, D. Ross Camidge, Hendrik-Tobias Arkenau, Timothy A. Yap
Purpose: OSI-930 is a novel, potent, oral small-molecule receptor tyrosine kinase inhibitor, predominantly against VEGF receptors (VEGFR), c-Kit, and platelet-derived growth factor receptors. A phase I trial was undertaken to determine safety, maximu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82c98a4c3811d944993686c53ba361a3
https://doi.org/10.1158/1078-0432.c.6521577
https://doi.org/10.1158/1078-0432.c.6521577
Autor:
Michelle Scurr, George Demetri, Stan B. Kaye, S. Gail Eckhardt, Andrew Stephens, Katie Brock, Richard Gedrich, Ramesh Boinpally, Srinivasu Poondru, Jon Chick, Martin O. Leach, Nandita M. Desouza, James Spicer, Rohit Lal, Jennifer L. Spratlin, Stephen J. Gwyther, Natalie J. Serkova, Suzanne George, D. Ross Camidge, Hendrik-Tobias Arkenau, Timothy A. Yap
PDF file - 72K, The semi-quantitative DCE-MRI endpoints for assessment of tumor perfusion (IAUC) and overall tumor vascularity (AUC)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a5607a677733b671f26e95dc87c8ee5
https://doi.org/10.1158/1078-0432.22449186.v1
https://doi.org/10.1158/1078-0432.22449186.v1
Autor:
Michelle Scurr, George Demetri, Stan B. Kaye, S. Gail Eckhardt, Andrew Stephens, Katie Brock, Richard Gedrich, Ramesh Boinpally, Srinivasu Poondru, Jon Chick, Martin O. Leach, Nandita M. Desouza, James Spicer, Rohit Lal, Jennifer L. Spratlin, Stephen J. Gwyther, Natalie J. Serkova, Suzanne George, D. Ross Camidge, Hendrik-Tobias Arkenau, Timothy A. Yap
PDF file - 58K, Changes in plasma sVEGFR2 over time in BID cohorts
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f22137cda9f40cc959dd82973be6fe3
https://doi.org/10.1158/1078-0432.22449207.v1
https://doi.org/10.1158/1078-0432.22449207.v1