Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Jennifer L. Shields"'
Autor:
Lindsey Gillis, Fadi Ghantous, Bronwyn M. Gunn, Christine A. Bricault, James M. Kovacs, James R. Perry, Michael S. Seaman, Nicole A. Doria-Rose, Kathryn E. Stephenson, George H. Neubauer, Bing Chen, Dan H. Barouch, Joseph P. Nkolola, John R. Mascola, Krisha McKee, Alexander Badamchi-Zadeh, Galit Alter, Jennifer L. Shields, Julia Jennings
Publikováno v:
Journal of Virology
A vaccination regimen capable of eliciting potent and broadly neutralizing antibodies (bNAbs) remains an unachieved goal of the HIV-1 vaccine field. Here, we report the immunogenicity of longitudinal prime/boost vaccination regimens with a panel of H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d59c314edf8b334d0f021f8396d5bdc
https://doi.org/10.1128/jvi.00369-18
https://doi.org/10.1128/jvi.00369-18
Autor:
Christine A. Bricault, Karina Yusim, Michael S. Seaman, Hyejin Yoon, James Theiler, Elena E. Giorgi, Kshitij Wagh, Maxwell Theiler, Peter Hraber, Jennifer P. Macke, Edward F. Kreider, Gerald H. Learn, Beatrice H. Hahn, Johannes F. Scheid, James M. Kovacs, Jennifer L. Shields, Christy L. Lavine, Fadi Ghantous, Michael Rist, Madeleine G. Bayne, George H. Neubauer, Katherine McMahan, Hanqin Peng, Coraline Chéneau, Jennifer J. Jones, Jie Zeng, Christina Ochsenbauer, Joseph P. Nkolola, Kathryn E. Stephenson, Bing Chen, S. Gnanakaran, Mattia Bonsignori, LaTonya D. Williams, Barton F. Haynes, Nicole Doria-Rose, John R. Mascola, David C. Montefiori, Dan H. Barouch, Bette Korber
Publikováno v:
Cell Host & Microbe
Summary Eliciting HIV-1-specific broadly neutralizing antibodies (bNAbs) remains a challenge for vaccine development, and the potential of passively delivered bNAbs for prophylaxis and therapeutics is being explored. We used neutralization data from
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3307527c90f358c3d9842a0665c9f1e
https://pubmed.ncbi.nlm.nih.gov/31415756
https://pubmed.ncbi.nlm.nih.gov/31415756
Autor:
Christy L. Lavine, Dan H. Barouch, Leonidas Stamatatos, Bette T. Korber, Christine A. Bricault, Karina Yusim, Joseph P. Nkolola, Elena E. Giorgi, Bing Chen, Ann Cheung, James R. Perry, Katharine Ellingson-Strouss, Michael S. Seaman, James M. Kovacs, Glenda Gray, Cecelia Rademeyer, Jennifer L. Shields, Carolyn Williamson
Publikováno v:
Journal of Virology. 89:2507-2519
The sequence diversity of human immunodeficiency virus type 1 (HIV-1) presents a formidable challenge to the generation of an HIV-1 vaccine. One strategy to address such sequence diversity and to improve the magnitude of neutralizing antibodies (NAbs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36b82432d83c0783a30c66c06a2e2c55
https://doi.org/10.1128/jvi.03331-14
https://doi.org/10.1128/jvi.03331-14
Autor:
Ann Cheung, James R. Perry, Jennifer L. Shields, Margot van Winsen, Christine A. Bricault, Adrian Constantin Apetri, Elena E. Giorgi, Bing Chen, Dan H. Barouch, Joseph P. Nkolola, Bette T. Korber, Michael S. Seaman, James M. Kovacs, Els C. M. Brinkman-Van der Linden
Publikováno v:
Journal of Virology. 88:9538-9552
The extraordinary diversity of the human immunodeficiency virus type 1 (HIV-1) envelope (Env) glycoprotein poses a major challenge for the development of an HIV-1 vaccine. One strategy to circumvent this problem utilizes bioinformatically optimized m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92efbb23c28b9df6248d19a6b96c2ea4
https://doi.org/10.1128/jvi.01739-14
https://doi.org/10.1128/jvi.01739-14
Autor:
James B. Whitney, Joseph Hesselgesser, Stephen Blackmore, Jerome H. Kim, Crystal Cabral, Erica N. Borducchi, Daniel I. S. Rosenbloom, Pablo Penaloza-MacMaster, Lauren Peter, Jennifer L. Shields, Jinyan Liu, Sheeba I. Mathew, Alison L. Hill, Merlin L. Robb, Srisowmya Sanisetty, Bei Li, Amanda L. Brinkman, Jillian Hattersley, Romas Geleziunas, Mayuri Shetty, Mark G. Lewis, Kaitlin M. Smith, Jeffrey Y. Smith, Dan H. Barouch, Lily Parenteau, Nelson L. Michael
Publikováno v:
Nature
The viral reservoir represents a critical challenge for human immunodeficiency virus type 1 (HIV-1) eradication strategies. However, it remains unclear when and where the viral reservoir is seeded during acute infection and the extent to which it is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96eacd61efc19756c0a08ffe57ca045c
https://doi.org/10.1038/nature13594
https://doi.org/10.1038/nature13594
Autor:
Thomas P. Monath, Quazim A. Alayo, Christine A. Bricault, Jessica Jimenez, Daniel D. Pinschewer, Dan H. Barouch, Jennifer L. Shields, Bastien Mangeat, Gerhard Fuhrmann, Klaus Orlinger, Pablo Penaloza MacMaster, Abishek Chandrashekar, Anders Lilja, Matthew Lim, Jade Mondesir, M. Justin Iampietro, Nicholas M. Provine, Crystal Cabral, Andreas Aspoeck, Joseph M Cabral, Michael S. Seaman
Publikováno v:
Vaccine. 35(1)
An important focus in vaccine research is the design of vaccine vectors with low seroprevalence and high immunogenicity. Replication-incompetent lymphocytic choriomeningitis virus (rLCMV) vectors do not elicit vector-neutralizing antibody responses,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa332fd93d7758cb40287ce054905ad4
https://pubmed.ncbi.nlm.nih.gov/27899229
https://pubmed.ncbi.nlm.nih.gov/27899229
Autor:
Michael S. Seaman, Christine A. Bricault, Eric S. Rosenberg, Nikolaus Pawlowski, Tobias Knaute, Jennifer L. Shields, Johannes Zerweck, Kathryn E. Stephenson, Madeleine Bayne, George H. Neubauer, Dan H. Barouch, Ulf Reimer
Publikováno v:
Open Forum Infectious Diseases
The examination of antibody responses in human immunodeficiency virus (HIV)-1-infected individuals in the setting of antiretroviral treatment (ART) interruption can provide insight into the evolution of antibody responses during viral rebound. In thi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::750a696f9cb9a72327fff3ae18a43a9a
https://doi.org/10.1093/ofid/ofw100
https://doi.org/10.1093/ofid/ofw100
Autor:
Kaitlin M. Smith, Christy L. Lavine, Jeffrey D. Lifson, Holger Wenschuh, Gerald Voss, James R. Perry, Jennifer L. Shields, Michael Piatak, James B. Whitney, Arnaud D. Colantonio, Dan H. Barouch, Mo Weijtens, Joseph P. Nkolola, Thomas Broge, Bing Chen, Mark G. Lewis, Eric P. Brown, David Ng’ang’a, Wenjun Li, Maria G. Pau, Herbert W. Virgin, Scott A. Handley, Lily Parenteau, Peter Abbink, Ulf Reimer, Jinyan Liu, Caitlyn Linde, Margaret E. Ackerman, Marguerite Koutsoukos, Erica N. Borducchi, Clarisse Lorin, Hanneke Schuitemaker, Galit Alter, Michael S. Seaman
Publikováno v:
Science (New York, N.Y.). 349(6245)
To defeat SIV, add a protein boost Despite 30 years of effort, no HIV-1 vaccine exists. Barouch et al. evaluated one promising strategy in rhesus macaques, a preclinical model commonly used to test potential HIV-1 vaccine candidates. They immunized m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5b4fbe394bf67b136c19b8dd320afd0
https://pubmed.ncbi.nlm.nih.gov/26138104
https://pubmed.ncbi.nlm.nih.gov/26138104