Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Jennifer L. Seymour"'
Autor:
William M. Hardesty, Fangming Xia, Armina Madatian, Ernest M. Schubert, Peter D. Gorycki, Yanli Deng, Jennifer L. Seymour, Catherine D. Tsalta
Publikováno v:
Drug Metabolism and Disposition. 39:1620-1632
GSK977779 is a potent HM74a agonist evaluated for the treatment of dyslipidemia. The disposition and metabolism of [(14)C]GSK977779 (67.6 μmol/kg p.o.) was studied in male and female rats. The compound was well absorbed and its primary route of elim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09774896aa3f9dafaf3900a6619ec5ab
https://doi.org/10.1124/dmd.110.036467
https://doi.org/10.1124/dmd.110.036467
Autor:
Sanjeev K. Dey, J. Fraser Stoddart, Ali Coskun, Mark A. Olson, William A. Goddard, Ali Trabolsi, Walter F. Paxton, Georgina M. Rosair, Stuart T. Caldwell, Gokhan Barin, Diego Benitez, Ekaterina Tkatchouk, Florence Duclairoir, Amy A. Sarjeant, Jennifer L. Seymour, Ross S. Forgan, Graeme Cooke, Shanika Gunatilaka Hewage, Michael R. Wasielewski, Albert C. Fahrenbach, Douglas C. Friedman, Raanan Carmielli, Michael T. Colvin, Jason M. Spruell, Alexandra M. Z. Slawin
Publikováno v:
Nature Chemistry. 2:870-879
Two [3]catenane ‘molecular flasks’ have been designed to create stabilized, redox-controlled tetrathiafulvalene (TTF) dimers, enabling their spectrophotometric and structural properties to be probed in detail. The mechanically interlocked framewo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9af78758bbc4640033acf5878b2528da
https://doi.org/10.1038/nchem.749
https://doi.org/10.1038/nchem.749
Publikováno v:
Journal of the American Society for Mass Spectrometry. 17:844-854
For the analysis of native glycans using tandem mass spectrometry (MS), it is desirable to choose conditions whereby abundances of cross-ring cleavages indicative of branch positions are maximized. Recently, negative ion tandem mass spectrometry has
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02f0f46403f8fa251e73851a4d653105
https://doi.org/10.1016/j.jasms.2006.02.022
https://doi.org/10.1016/j.jasms.2006.02.022
Publikováno v:
Journal of Mass Spectrometry. 39:1044-1052
This study was focused on distinguishing L- and D-enantiomers of amino acids using electrospray ionization mass spectrometry (ESI-MS) of ternary complexes with Cu(II) and chiral derivatives of bipyridine. A pinene-annulated derivative of 2,2′-bipyr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa56bd0394611070184f4ef15e6e924f
https://doi.org/10.1002/jms.675
https://doi.org/10.1002/jms.675
Publikováno v:
International Journal of Mass Spectrometry. 228:687-702
A tandem mass spectrometer is described for neutralization–reionization studies of ions produced by electrospray ionization. The instrument consists of a high current electrospray source, an electrodynamic ion funnel, and an octopole ion guide that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ab2be8a5ff4fb95b2ba0ae7e35c9ef7f
https://doi.org/10.1016/s1387-3806(03)00217-3
https://doi.org/10.1016/s1387-3806(03)00217-3
Autor:
Jennifer L. Seymour, František Tureček
Publikováno v:
Journal of Mass Spectrometry. 37:533-540
The structures, electron distributions and dissociation energies of gas-phase ternary complexes of Cu(II) with 2,2'-bipyridine and leucine, isoleucine and lysine were addressed by density functional theory using the hybrid B3LYP functional, effective
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::faf9895626a3d15ded3a80450b2ff363
https://doi.org/10.1002/jms.311
https://doi.org/10.1002/jms.311
Autor:
Jennifer L. Seymour, František Tureček
Publikováno v:
Journal of Mass Spectrometry. 35:566-571
Electrospray ionization of mixtures of isomeric and isobaric amino acids was investigated with the goal of distinguishing and quantifying the components. Isomeric amino acids leucine and isoleucine were readily distinguished and quantified in 90 : 10
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a202187432bd0afe3c2bcbcf716a7885
https://doi.org/10.1002/(sici)1096-9888(200004)35:4<566::aid-jms970>3.0.co
https://doi.org/10.1002/(sici)1096-9888(200004)35:4<566::aid-jms970>3.0.co
Publikováno v:
The journal of physical chemistry. A. 111(36)
Diaminohydroxymethyl (1) and triaminomethyl (2) radicals were generated by femtosecond collisional electron transfer to their corresponding cations (1+ and 2+, respectively) and characterized by neutralization-reionization mass spectrometry and ab in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec5921365fa872a6a021c54c72ed48be
https://pubmed.ncbi.nlm.nih.gov/17705355
https://pubmed.ncbi.nlm.nih.gov/17705355
Publikováno v:
Journal of the American Society for Mass Spectrometry. 18(5)
Carbohydrates of all classes consist of glycoform mixtures built on common core units. Determination of compositions and structures of such mixtures relies heavily on tandem mass spectrometric data. Analysis of native glycans is often necessary for s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53fbc7483959cdcb2b30f27f409b89c9
https://pubmed.ncbi.nlm.nih.gov/17383193
https://pubmed.ncbi.nlm.nih.gov/17383193
Publikováno v:
Journal of mass spectrometry : JMS. 40(5)
Gas-phase ternary complexes with Cu(II) and 2,2′-bipyridine (bpy) of tyrosine, 3-aminotyrosine, 3-nitrotyrosine and 3-nitrotyrosine methyl ether are formed readily upon electrospraying aqueous methanol solutions containing the components. In contra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2aa3f3ce7389cc9e848a4ac88112fec
https://pubmed.ncbi.nlm.nih.gov/15724273
https://pubmed.ncbi.nlm.nih.gov/15724273