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pro vyhledávání: '"Jennifer L. McEldoon"'
Autor:
Sidinh Luc, Jialiang Huang, Jennifer L. McEldoon, Ece Somuncular, Dan Li, Claire Rhodes, Shahan Mamoor, Serena Hou, Jian Xu, Stuart H. Orkin
Publikováno v:
Cell Reports, Vol 16, Iss 12, Pp 3181-3194 (2016)
B cell CLL/lymphoma 11A (BCL11A) is a transcription factor and regulator of hemoglobin switching that has emerged as a promising therapeutic target for sickle cell disease and thalassemia. In the hematopoietic system, BCL11A is required for B lymphop
Externí odkaz:
https://doaj.org/article/f4352ddea809447e87cd65eb97af8621
Autor:
Dan Li, Claire Rhodes, Shahan Mamoor, Jialiang Huang, Jian Xu, Stuart H. Orkin, Ece Somuncular, Sidinh Luc, Jennifer L. McEldoon, Serena Hou
Publikováno v:
Cell Reports, Vol 16, Iss 12, Pp 3181-3194 (2016)
SummaryB cell CLL/lymphoma 11A (BCL11A) is a transcription factor and regulator of hemoglobin switching that has emerged as a promising therapeutic target for sickle cell disease and thalassemia. In the hematopoietic system, BCL11A is required for B
Autor:
Matthew C. Canver, Jeremy Allred, Stuart H. Orkin, Jennifer L. McEldoon, Glenn A. MacLean, Jialiang Huang
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-10 (2018)
Scientific Reports
Scientific Reports
Individuals with Trisomy 21 (T21) exhibit numerous hematological abnormalities, including reductions in numbers of circulating B and T lymphocytes. To elucidate molecular mechanisms underlying these phenotypes, we differentiated human isogenic disomi