Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Jennifer L. MacDonald"'
Autor:
Jennifer L. Macdonald, Linda J. Pike
Publikováno v:
Journal of Lipid Research, Vol 46, Iss 5, Pp 1061-1067 (2005)
Lipid rafts are small plasma membrane domains that contain high levels of cholesterol and sphingolipids. Traditional methods for the biochemical isolation of lipid rafts involve the extraction of cells with nonionic detergents followed by the separat
Externí odkaz:
https://doaj.org/article/9cbee7d310484839bd397758bd197e7e
Coloured indicators, whether solution or paper based, are often used in laboratory courses and academic/industrial research as a qualitative method to test important experimental markers. While useful, these tools present challenges to those with col
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::697cbaa17c79bd53a7d793e04af024ca
https://doi.org/10.26434/chemrxiv-2023-6g77r
https://doi.org/10.26434/chemrxiv-2023-6g77r
Publikováno v:
Journal of Biological Chemistry. 292:20744-20755
The EGF receptor is a classic receptor tyrosine kinase. It contains nine tyrosines in its C-terminal tail, many of which are phosphorylated and bind proteins containing SH2 or phosphotyrosine-binding (PTB) domains. To determine how many and which tyr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41c353a0b607def8095f9220b9a7052d
https://doi.org/10.1074/jbc.m117.802553
https://doi.org/10.1074/jbc.m117.802553
Autor:
Linda J. Pike, Jennifer L. Macdonald-Obermann, Tom Ronan, Nicholas J. Bessman, Lorel Huelsmann, Kristen M. Naegle
Publikováno v:
Journal of Biological Chemistry. 291:5528-5540
The EGF receptor can bind seven different agonist ligands. Although each agonist appears to stimulate the same suite of downstream signaling proteins, different agonists are capable of inducing distinct responses in the same cell. To determine the ba
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3f39304abebb98a70e39d9aeec4d42d
https://doi.org/10.1074/jbc.m115.710087
https://doi.org/10.1074/jbc.m115.710087
The epidermal growth factor (EGF) receptor is a classical receptor tyrosine kinase with an extracellular ligand-binding domain and an intracellular kinase domain. Mutations in the EGF receptor have been shown to drive uncontrolled cell growth and are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ddea9c62c3bbac188ccd076ad385b94
https://europepmc.org/articles/PMC6120208/
https://europepmc.org/articles/PMC6120208/
Publikováno v:
Journal of Biological Chemistry. 289:26178-26188
The EGF receptor has seven different cognate ligands. Previous work has shown that these different ligands are capable of inducing different biological effects, even in the same cell. To begin to understand the molecular basis for this variation, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd2e26eb6a14d8583cd05728f06b9f10
https://doi.org/10.1074/jbc.m114.586826
https://doi.org/10.1074/jbc.m114.586826
Publikováno v:
Proceedings of the National Academy of Sciences. 109:137-142
Binding of EGF to its receptor induces dimerization of the normally monomeric receptor. Activation of its intracellular tyrosine kinase then occurs through the formation of an asymmetric kinase dimer in which one subunit, termed the “receiver” ki
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba12c8b94f8cfc90f1082d98b3861d15
https://doi.org/10.1073/pnas.1111316109
https://doi.org/10.1073/pnas.1111316109
Autor:
Jennifer L. MacDonald, C. Dale Keefe
Publikováno v:
Vibrational Spectroscopy. 44:121-132
The infrared refractive index, molar absorption coefficient and imaginary polarizability spectra of hexane presented in a previous paper are extended to 100 cm −1 . The vibrational assignment and curve fit of the imaginary molar polarizability spec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7b54563561d52177b4ea6dd965c5b5e0
https://doi.org/10.1016/j.vibspec.2006.10.003
https://doi.org/10.1016/j.vibspec.2006.10.003
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 1763:870-878
The EGF receptor is a transmembrane receptor tyrosine kinase that is enriched in lipid rafts. Subdomains I, II and III of the extracellular domain of the EGF receptor participate in ligand binding and dimer formation. However, the function of the cys
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06a25ccea830a5259b1d58a2b3c8605f
https://doi.org/10.1016/j.bbamcr.2006.05.002
https://doi.org/10.1016/j.bbamcr.2006.05.002
Autor:
C. Dale Keefe, Jennifer L. MacDonald
Publikováno v:
Vibrational Spectroscopy. 40:168-176
This paper is a continuation of the study of the integrated absorption intensities of benzene and its simple derivatives. In this paper, the imaginary molar polarizability spectrum reported earlier for fluorobenzene was fit with 169 classical damped
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::40f11b6e21e253974d9ae46d981e1066
https://doi.org/10.1016/j.vibspec.2005.08.003
https://doi.org/10.1016/j.vibspec.2005.08.003