Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Jennifer L. Leight"'
Autor:
Priya H. Dedhia, Hemamylammal Sivakumar, Marco A. Rodriguez, Kylie G. Nairon, Joshua M. Zent, Xuguang Zheng, Katie Jones, Liudmila V. Popova, Jennifer L. Leight, Aleksander Skardal
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract Adrenocortical carcinoma (ACC) has a poor prognosis, and no new drugs have been identified in decades. The absence of drug development can partly be attributed to a lack of preclinical models. Both animal models and 2D cell cultures of ACC f
Externí odkaz:
https://doaj.org/article/b1b85de5b9c44c18b6df603e0e5919b5
Publikováno v:
iScience, Vol 25, Iss 7, Pp 104645- (2022)
Summary: Primary tumors secrete large quantities of cytokines and exosomes into the bloodstream, which are uptaken at downstream sites and induce a pro-fibrotic, pro-inflammatory premetastatic niche. Niche development is associated with later increas
Externí odkaz:
https://doaj.org/article/241cba1c022542f79a57b16e333d0223
Autor:
Clarissa Wormsbaecher, Andrea R. Hindman, Alex Avendano, Marcos Cortes-Medina, Caitlin E. Jones, Andrew Bushman, Lotanna Onua, Claire E. Kovalchin, Alina R. Murphy, Hannah L. Helber, Ali Shapiro, Kyle Voytovitch, Xingyan Kuang, Renan Aguilar-Valenzuela, Jennifer L. Leight, Jonathan W. Song, Craig J. Burd
Publikováno v:
Breast Cancer Research, Vol 22, Iss 1, Pp 1-12 (2020)
Abstract Background In utero endocrine disruption is linked to increased risk of breast cancer later in life. Despite numerous studies establishing this linkage, the long-term molecular changes that predispose mammary cells to carcinogenic transforma
Externí odkaz:
https://doaj.org/article/06289fcf953349bf8b69644304328452
Autor:
Caitlin E. Jones, Anisha M. Hammer, YouJin Cho, Gina M. Sizemore, Edna Cukierman, Lisa D. Yee, Samir N. Ghadiali, Michael C. Ostrowski, Jennifer L. Leight
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 21, Iss 1, Pp 132-145 (2019)
The organization of the extracellular matrix has a profound impact on cancer development and progression. The matrix becomes aligned throughout tumor progression, providing “highways” for tumor cell invasion. Aligned matrix is associated with bre
Externí odkaz:
https://doaj.org/article/fb890cfa8be04e6385066d38ace09c7d
Autor:
Sayumi Tahara, Fernanda Costas C. de Faria, Patricia Sarchet, Federica Calore, Joe Sharick, Jennifer L. Leight, Lucia Casadei, Raphael E. Pollock
Publikováno v:
Human Cell. 36:1081-1089
Autor:
Caitlin E. Jones, Joe T. Sharick, Steven T. Sizemore, Edna Cukierman, Anne Marie Strohecker, Jennifer L. Leight
Publikováno v:
Cancer Res Commun
Extracellular matrix (ECM) alignment contributes to metastasis in a number of cancers and is a known prognostic stromal factor; however, the mechanisms controlling matrix organization remain unclear. Cancer-associated fibroblasts (CAF) play a critica
Publikováno v:
Journal of Biomedical Materials Research Part A. 111:389-403
Self-assembling peptide (SAP) hydrogels provide a fibrous microenvironment to cells while also giving users control of biochemical and mechanical cues. Previously, biochemical cues were introduced by physically mixing them with SAPs prior to hydrogel
Autor:
Jennifer L. Leight, Anne Marie Strohecker, Edna Cukierman, Steven T. Sizemore, Joe T. Sharick, Caitlin E. Jones
Figure S1, S2, S3, Table S1 and S2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::470a2199c9615c25a9055293c1b0d24a
https://doi.org/10.1158/2767-9764.22546143.v1
https://doi.org/10.1158/2767-9764.22546143.v1
Autor:
Jennifer L. Leight, Anne Marie Strohecker, Edna Cukierman, Steven T. Sizemore, Joe T. Sharick, Caitlin E. Jones
Extracellular matrix (ECM) alignment contributes to metastasis in a number of cancers and is a known prognostic stromal factor; however, the mechanisms controlling matrix organization remain unclear. Cancer-associated fibroblasts (CAF) play a critica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::014d811363b82582fb69b125d15f4a0f
https://doi.org/10.1158/2767-9764.c.6551109
https://doi.org/10.1158/2767-9764.c.6551109
Autor:
Raphael E. Pollock, Carlo M. Croce, Dina Lev, Valerie P. Grignol, Jennifer L. Leight, Chi Song, Martin Wabitsch, Gonzalo Lopez, Paolo Fadda, Ameya A. Deshmukh, Abeba Zewdu, Danielle A. Braggio, Federica Calore, Lucia Casadei
Supplemental Figures are: SF1: Determination of number of molecules of MDM2 in the serum-EVs using Standard Curve Methodology. SF2: Quality control of cell line-isolated vesicles, performed through nanosight and western blot analyses. SF3: Nanosight
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00db14501e5c414e321a9d293e1f631e
https://doi.org/10.1158/0008-5472.22421712.v1
https://doi.org/10.1158/0008-5472.22421712.v1