Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Jennifer L. Gu"'
Autor:
Waruiru Mburu, Changyuan Guo, Yuan Tian, Hela Koka, Sheng Fu, Ning Lu, Erni Li, Jing Li, Renata Cora, Ariane Chan, Jennifer L. Guida, Hyuna Sung, Gretchen L. Gierach, Mustapha Abubakar, Kai Yu, Xiaohong R. Yang
Publikováno v:
Breast Cancer Research, Vol 26, Iss 1, Pp 1-12 (2024)
Abstract Background Higher mammographic density (MD), a radiological measure of the proportion of fibroglandular tissue in the breast, and lower terminal duct lobular unit (TDLU) involution, a histological measure of the amount of epithelial tissue i
Externí odkaz:
https://doaj.org/article/da2d57df18654fb99e53fd1aa7049e16
Autor:
Jennifer L. Guelfo, P. Lee Ferguson, Jonathan Beck, Melissa Chernick, Alonso Doria-Manzur, Patrick W. Faught, Thomas Flug, Evan P. Gray, Nishad Jayasundara, Detlef R. U. Knappe, Abigail S. Joyce, Pingping Meng, Marzieh Shojaei
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Lithium-ion batteries (LiBs) are used globally as a key component of clean and sustainable energy infrastructure, and emerging LiB technologies have incorporated a class of per- and polyfluoroalkyl substances (PFAS) known as bis-perfluoroalk
Externí odkaz:
https://doaj.org/article/c4b4fc873193428e89d51da7193464f2
Autor:
Jennifer L. Guerriero, Jia-Ren Lin, Ricardo G. Pastorello, Ziming Du, Yu-An Chen, Madeline G. Townsend, Kenichi Shimada, Melissa E. Hughes, Siyang Ren, Nabihah Tayob, Kelly Zheng, Shaolin Mei, Alyssa Patterson, Krishan L. Taneja, Otto Metzger, Sara M. Tolaney, Nancy U. Lin, Deborah A. Dillon, Stuart J. Schnitt, Peter K. Sorger, Elizabeth A. Mittendorf, Sandro Santagata
Publikováno v:
npj Breast Cancer, Vol 10, Iss 1, Pp 1-22 (2024)
Abstract Emerging data suggests that HER2 intratumoral heterogeneity (ITH) is associated with therapy resistance, highlighting the need for new strategies to assess HER2 ITH. A promising approach is leveraging multiplexed tissue analysis techniques s
Externí odkaz:
https://doaj.org/article/3efb1bd4ddfe4838842869755c17c107
Autor:
Jeffrey Patterson-Fortin, Heta Jadhav, Constantia Pantelidou, Tin Phan, Carter Grochala, Anita K. Mehta, Jennifer L. Guerriero, Gerburg M. Wulf, Brian M. Wolpin, Ben Z. Stanger, Andrew J. Aguirre, James M. Cleary, Alan D. D’Andrea, Geoffrey I. Shapiro
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Abstract Recently developed inhibitors of polymerase theta (POLθ) have demonstrated synthetic lethality in BRCA-deficient tumor models. To examine the contribution of the immune microenvironment to antitumor efficacy, we characterized the effects of
Externí odkaz:
https://doaj.org/article/1a29347110de4ea98e7dbf7d5ea3b928
Autor:
Constantia Pantelidou, Heta Jadhav, Aditi Kothari, Renyan Liu, Gerburg M. Wulf, Jennifer L. Guerriero, Geoffrey I. Shapiro
Publikováno v:
npj Breast Cancer, Vol 8, Iss 1, Pp 1-6 (2022)
Abstract Poly (ADP-ribose) polymerase (PARP) inhibitors exert their efficacy via synthetic lethal effects and by inducing cGAS/STING-mediated immune responses. We demonstrate that compared to monotherapies, combined PARP inhibition and STING agonism
Externí odkaz:
https://doaj.org/article/7b01ec196cd24865ad3f63193e80c79b
Publikováno v:
mBio, Vol 14, Iss 3 (2023)
ABSTRACT Mounting evidence demonstrates that nutritional environment can alter pathogen drug sensitivity. While the rich media used for in vitro culture contains supraphysiological nutrient concentrations, pathogens encounter a relatively restrictive
Externí odkaz:
https://doaj.org/article/89801be502ff418daa6cd7929ded9d74
Autor:
Dilorom Sass, Brennan Parmelee Streck, Vivian A. Guedes, Diane Cooper, Jennifer L. Guida, Terri S. Armstrong
Publikováno v:
Frontiers in Public Health, Vol 11 (2023)
This review examines the current literature to identify biomarkers of frailty across patients with solid tumors. We conducted the systematic review using preferred reporting items for systematic reviews and meta-analysis guidelines (PRISMA). PubMed,
Externí odkaz:
https://doaj.org/article/7c2a0825036c434abcb55a86b7baf383
Publikováno v:
Developmental Cell. 10:707-718
Heterotrimeric G proteins are critical cellular signal transducers. They are known to directly relay signals from seven-transmembrane G protein-coupled receptors (GPCRs) to downstream effectors. On the other hand, receptor tyrosine kinases (RTKs), a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a7c055d36920b9aa8e6779f0886222e
https://doi.org/10.1016/j.devcel.2006.03.014
https://doi.org/10.1016/j.devcel.2006.03.014
Autor:
Hongxiu Qi, Xuping Wang, Jack Wong, Aldons J. Lusis, Lawrence W. Castellani, Peter S. Gargalovic, Li Xi, Jennifer L. Gu, Rocky G. Gogliotti, Bing Tan, Aurobindo Chatterjee, Xiaohui Wu, Ping-Zi Wen
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 24:1928-1934
Objective— We previously reported the mapping of a quantitative trait locus (QTL) on chromosome 15 contributing to hyperlipidemia in a cross between inbred strains MRL/MpJ (MRL) and BALB/cJ (BALB). Using marker-assisted breeding, we constructed a c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4391fcbc25aecf6bf4ce77471fb4d9f
https://doi.org/10.1161/01.atv.0000143385.30354.bb
https://doi.org/10.1161/01.atv.0000143385.30354.bb
Autor:
Jeffrey Patterson-Fortin, Heta Jadhav, Constantia Pantelidou, Tin Phan, Carter Grochala, Anita K. Mehta, Jennifer L. Guerriero, Gerburg M. Wulf, Brian M. Wolpin, Ben Z. Stanger, Andrew J. Aguirre, James M. Cleary, Alan D. D’Andrea, Geoffrey I. Shapiro
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-1 (2023)
Externí odkaz:
https://doaj.org/article/82e85d38c2f441d4a07b0dc1341b7616