Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Jennifer L. Groebner"'
Autor:
Yuta Hikichi, Rachel Van Duyne, Phuong Pham, Jennifer L. Groebner, Ann Wiegand, John W. Mellors, Mary F. Kearney, Eric O. Freed
Publikováno v:
mBio, Vol 12, Iss 1 (2021)
Although combination antiretroviral (ARV) therapy is highly effective in controlling the progression of HIV disease, drug resistance can be a major obstacle. Recent findings suggest that resistance can develop without ARV target gene mutations.
Externí odkaz:
https://doaj.org/article/a4bd72fa01324caca28f6cbce9932f14
Publikováno v:
Viruses, Vol 13, Iss 5, p 795 (2021)
Natural antisense transcripts (NATs) represent a class of RNA molecules that are transcribed from the opposite strand of a protein-coding gene, and that have the ability to regulate the expression of their cognate protein-coding gene via multiple mec
Externí odkaz:
https://doaj.org/article/506484c7640042b6bf74fdbcd2459ef5
Autor:
Manuela G. Neuman, Helmut Karl Seitz, Samuel W. French, Stephen Malnick, Heidekazu Tsukamoto, Lawrence B. Cohen, Paula Hoffman, Boris Tabakoff, Michael Fasullo, Laura E. Nagy, Pamela L. Tuma, Bernd Schnabl, Sebastian Mueller, Jennifer L. Groebner, French A. Barbara, Jia Yue, Afifiyan Nikko, Mendoza Alejandro, Tillman Brittany, Vitocruz Edward, Kylie Harrall, Laura Saba, Opris Mihai
Publikováno v:
Biomedicines, Vol 8, Iss 3, p 63 (2020)
The following review article presents clinical and experimental features of alcohol-induced liver disease (ALD). Basic aspects of alcohol metabolism leading to the development of liver hepatotoxicity are discussed. ALD includes fatty liver, acute alc
Externí odkaz:
https://doaj.org/article/55bb8d22f29247d8b0b4e7e71397ea54
Autor:
Jennifer L. Groebner, Pamela L. Tuma
Publikováno v:
Biomolecules, Vol 5, Iss 3, Pp 2140-2159 (2015)
The molecular mechanisms that lead to the progression of alcoholic liver disease have been actively examined for decades. Because the hepatic microtubule cytoskeleton supports innumerable cellular processes, it has been the focus of many such mechani
Externí odkaz:
https://doaj.org/article/b2abf9b719884827ab9df7c3fd8ee9af
Publikováno v:
Viruses, Vol 13, Iss 795, p 795 (2021)
Viruses
Viruses
Natural antisense transcripts (NATs) represent a class of RNA molecules that are transcribed from the opposite strand of a protein-coding gene, and that have the ability to regulate the expression of their cognate protein-coding gene via multiple mec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45e0c51577155ec7ad063ec18a5cf579
https://www.mdpi.com/1999-4915/13/5/795
https://www.mdpi.com/1999-4915/13/5/795
Autor:
Ann Wiegand, Phuong Pham, Mary F. Kearney, Rachel Van Duyne, Eric O. Freed, Yuta Hikichi, Jennifer L. Groebner, John W. Mellors
Publikováno v:
mBio, Vol 12, Iss 1 (2021)
mBio
mBio
Although combination antiretroviral (ARV) therapy is highly effective in controlling the progression of HIV disease, drug resistance can be a major obstacle. Recent findings suggest that resistance can develop without ARV target gene mutations.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed77ffda97de7ac2a51cc6ac60b18020
https://doi.org/10.1128/mbio.03134-20
https://doi.org/10.1128/mbio.03134-20
Autor:
Jennifer L. Groebner, Laura E. Nagy, Helmut K. Seitz, Lawrence Cohen, Afifiyan Nikko, Vitocruz Edward, Samuel W. French, Sebastian Mueller, Kylie K. Harrall, Pamela L. Tuma, Manuela G. Neuman, Opris Mihai, Laura Saba, Heidekazu Tsukamoto, Mendoza Alejandro, Michael Fasullo, Paula L. Hoffman, Boris Tabakoff, Jia Yue, Stephen Malnick, French A. Barbara, Tillman Brittany, Bernd Schnabl
Publikováno v:
Biomedicines
Biomedicines, vol 8, iss 3
Biomedicines, Vol 8, Iss 3, p 63 (2020)
Biomedicines, vol 8, iss 3
Biomedicines, Vol 8, Iss 3, p 63 (2020)
The following review article presents clinical and experimental features of alcohol-induced liver disease (ALD). Basic aspects of alcohol metabolism leading to the development of liver hepatotoxicity are discussed. ALD includes fatty liver, acute alc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb24183bfae96be240540435639e6b52
http://europepmc.org/articles/PMC7148515
http://europepmc.org/articles/PMC7148515
Autor:
Jetta R. Walker, David J. Fernandez, Pamela L. Tuma, Dean J. Tuma, Erin E. Doody, Jennifer L. Groebner, Brittnee M. Frizol
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 313:G558-G569
Impaired growth hormone-mediated signaling is observed in ethanol-exposed hepatocytes and is explained by differential effects of alcohol dehydrogenase (ADH)- and cytochrome P4502E1 (CYP2E1)-mediated ethanol metabolism on the Jak2/STAT5B pathway.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b0c8b3943d1d0e88f3b433d6fed61107
https://doi.org/10.1152/ajpgi.00027.2017
https://doi.org/10.1152/ajpgi.00027.2017
Autor:
Erin E, Doody, Jennifer L, Groebner, Jetta R, Walker, Brittnee M, Frizol, Dean J, Tuma, David J, Fernandez, Pamela L, Tuma
Publikováno v:
American journal of physiology. Gastrointestinal and liver physiology. 313(6)
Impaired growth hormone-mediated signaling is observed in ethanol-exposed hepatocytes and is explained by differential effects of alcohol dehydrogenase (ADH)- and cytochrome P450 2E1 (CYP2E1)-mediated ethanol metabolism on the Jak2/STAT5B pathway.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2e7e8c3366c8c3dd562e7f3c74bdb464
https://pubmed.ncbi.nlm.nih.gov/28864499
https://pubmed.ncbi.nlm.nih.gov/28864499
Autor:
John M. Dye, Samantha E. Zak, James F. Barth, Andrew S. Herbert, Majidat A. Muhammad, Kurt Kamrud, Ana I. Kuehne, Mary Kate Hart, Ramon A. Ortiz, Gene G. Olinger, Jennifer L. Groebner, Donald K. Nichols, William D. Pratt, Jonathan F. Smith, John S. Lee, Spencer W. Stonier, Max Custer, Russell R. Bakken, Laura I. Prugar
Publikováno v:
Journal of Virology. 87:4952-4964
There are no vaccines or therapeutics currently approved for the prevention or treatment of ebolavirus infection. Previously, a replicon vaccine based on Venezuelan equine encephalitis virus (VEEV) demonstrated protective efficacy against Marburg vir
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2e7f0920bdd4b6b0ad633aec7ec4c72
https://doi.org/10.1128/jvi.03361-12
https://doi.org/10.1128/jvi.03361-12