Zobrazeno 1 - 10
of 98
pro vyhledávání: '"Jennifer L. DuBois"'
Autor:
Krista A. Shisler, William M. Kincannon, Jenna R. Mattice, James Larson, Adam Valaydon-Pillay, Florence Mus, Tamara Flusche, Arnab Kumar Nath, Sebastian A. Stoian, Simone Raugei, Brian Bothner, Jennifer L. DuBois, John W. Peters
Publikováno v:
mBio, Vol 15, Iss 2 (2024)
ABSTRACT Acetone carboxylases (ACs) catalyze the metal- and ATP-dependent conversion of acetone and bicarbonate to form acetoacetate. Interestingly, two homologous ACs that have been biochemically characterized have been reported to have different me
Externí odkaz:
https://doaj.org/article/7a957b0e440a4b67b606f1f3d09be52c
Autor:
Erika Erickson, Japheth E. Gado, Luisana Avilán, Felicia Bratti, Richard K. Brizendine, Paul A. Cox, Raj Gill, Rosie Graham, Dong-Jin Kim, Gerhard König, William E. Michener, Saroj Poudel, Kelsey J. Ramirez, Thomas J. Shakespeare, Michael Zahn, Eric S. Boyd, Christina M. Payne, Jennifer L. DuBois, Andrew R. Pickford, Gregg T. Beckham, John E. McGeehan
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
Enzymes have potential for recycling plastics such as PET, a polyester used in textiles and single-use packaging. Here, the authors identify and characterize additional PET-active biocatalysts and expand the number and diversity of thermotolerant sca
Externí odkaz:
https://doaj.org/article/948513aa5c164d4e92b945bb6ce6fa3b
Autor:
Emerald S. Ellis, Daniel J. Hinchen, Alissa Bleem, Lintao Bu, Sam J. B. Mallinson, Mark D. Allen, Bennett R. Streit, Melodie M. Machovina, Quinlan V. Doolin, William E. Michener, Christopher W. Johnson, Brandon C. Knott, Gregg T. Beckham, John E. McGeehan, Jennifer L. DuBois
Publikováno v:
JACS Au, Vol 1, Iss 3, Pp 252-261 (2021)
Externí odkaz:
https://doaj.org/article/6f2df64545844e09b982f065a13ea668
Autor:
Sam J. B. Mallinson, Melodie M. Machovina, Rodrigo L. Silveira, Marc Garcia-Borràs, Nathan Gallup, Christopher W. Johnson, Mark D. Allen, Munir S. Skaf, Michael F. Crowley, Ellen L. Neidle, Kendall N. Houk, Gregg T. Beckham, Jennifer L. DuBois, John E. McGeehan
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
Catabolizing lignin-derived aromatic compounds requires an aryl-O-demethylation step. Here the authors present the structures of GcoA and GcoB, a cytochrome P450-reductase pair that catalyzes aryl-O-demethylations and show that GcoA displays broad su
Externí odkaz:
https://doaj.org/article/794b35c1169a406b89565b7b8ae40208
Autor:
Florence Mus, Brian J. Eilers, Alexander B. Alleman, Burak V. Kabasakal, Jennifer N. Wells, James W. Murray, Boguslaw P. Nocek, Jennifer L. DuBois, John W. Peters
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-10 (2017)
Abstract Microorganisms use carboxylase enzymes to form new carbon-carbon bonds by introducing carbon dioxide gas (CO2) or its hydrated form, bicarbonate (HCO3 −), into target molecules. Acetone carboxylases (ACs) catalyze the conversion of substra
Externí odkaz:
https://doaj.org/article/974d0ab5c0a34d4b9a8c4a31370e6562
Staphylococcus aureus HemX Modulates Glutamyl-tRNA Reductase Abundance To Regulate Heme Biosynthesis
Autor:
Jacob E. Choby, Caroline M. Grunenwald, Arianna I. Celis, Svetlana Y. Gerdes, Jennifer L. DuBois, Eric P. Skaar
Publikováno v:
mBio, Vol 9, Iss 1 (2018)
ABSTRACT Staphylococcus aureus is responsible for a significant amount of devastating disease. Its ability to colonize the host and cause infection is supported by a variety of proteins that are dependent on the cofactor heme. Heme is a porphyrin use
Externí odkaz:
https://doaj.org/article/405059706deb49fc97647c9d061a40c4
Publikováno v:
Microbiology Spectrum. 11
Research on bacterial iron metabolism has historically focused on the host-pathogen relationship, where the host suppresses pathogen growth by cutting off access to iron. Less is known about how host iron is shared with bacterial species that live co
Autor:
Hsin-Hua Wu, Michael D. Pun, Courtney E. Wise, Bennett R. Streit, Florence Mus, Anna Berim, William M. Kincannon, Abdullah Islam, Sarah E. Partovi, David R. Gang, Jennifer L. DuBois, Carolyn E. Lubner, Clifford E. Berkman, B. Markus Lange, John W. Peters
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 119(36)
Mercaptoethane sulfonate or coenzyme M (CoM) is the smallest known organic cofactor and is most commonly associated with the methane-forming step in all methanogenic archaea but is also associated with the anaerobic oxidation of methane to CO 2 in an
Autor:
Erika Erickson, Alissa Bleem, Eugene Kuatsjah, Allison Z. Werner, Jennifer L. DuBois, John E. McGeehan, Lindsay D. Eltis, Gregg T. Beckham
Publikováno v:
Nature Catalysis. 5:86-98
Publikováno v:
Current Opinion in Biotechnology. 73:43-50
The valorization of lignin is critical to establishing sustainable biorefineries as we transition away from petroleum-derived feedstocks. Advances in lignin fractionation and depolymerization are yielding new opportunities for the biocatalytic upgrad