Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Jennifer L. Cantley"'
Autor:
Lisa Chung, Lloyd G. Cantley, Justin M. Belcher, Thomas Abbott, Kathryn L. Stone, Jennifer L. Cantley, Kenneth R. Williams, Chirag R. Parikh, Christopher M. Colangelo
Publikováno v:
PROTEOMICS - Clinical Applications. 10:58-74
Purpose Since human urine is the most readily available biofluid whose proteome changes in response to disease, it is a logical sample for identifying protein biomarkers for kidney diseases. Experimental design Potential biomarkers were identified by
Autor:
Neera K. Dahl, Chirag R. Parikh, Kathryn L. Stone, Lloyd G. Cantley, Justin M. Belcher, Navin Rauniyar, Christopher M. Colangelo, Xiaoqing Yu, TuKiet T. Lam, Edward Z. Voss, Jennifer L. Cantley
Publikováno v:
Proteomics. Clinical applications. 12(5)
Purpose Autosomal dominant polycystic kidney disease (ADPKD) is a life-long disease in which the genes responsible are known, but the pathogenesis of cyst formation and cyst growth are not understood. Cyst growth ultimately leads to end-stage renal f
Autor:
Jennifer L. Cantley, Naoki Kumashiro, Mario Kahn, Glenn S. Gerhard, Derek M. Erion, Sanjay Bhanot, Gary W. Cline, Dongyan Zhang, Romy Kursawe, Kitt Falk Petersen, Fitsum Guebre-Egziabher, Gerald I. Shulman, Ioana Fat, Toru Yoshimura, Sachin Majumdar, Daniel F. Vatner, Vara Prasad Manchem, Varman T. Samuel, Xian-Man Zhang
Publikováno v:
Hepatology (Baltimore, Md.)
Genome-wide array studies have associated the patatin-like phospholipase domain-containing 3 (PNPLA3) gene polymorphisms with hepatic steatosis. However, it is unclear whether PNPLA3 functions as a lipase or a lipogenic enzyme and whether PNPLA3 is i
Autor:
Donald P. Dione, Albert J. Sinusas, Jennifer L. Cantley, Christopher E. Hall, Daniel F. Vatner, Louis Ragolia, Sanjay Bhanot, Fitsum Guebre-Egziabher, Vara Prasad Manchem, Varman T. Samuel, Max C. Petersen, Thomas Galbo, Arijeet K. Gattu, Mitchel R. Stacy, Rachel J. Perry, Naoki Kumashiro, Jonathan S. Bogan, Anila K. Madiraju
Publikováno v:
American journal of physiology. Endocrinology and metabolism. 307(9)
The steroid receptor coactivator 1 (SRC1) regulates key metabolic pathways, including glucose homeostasis. SRC1−/− mice have decreased hepatic expression of gluconeogenic enzymes and a reduction in the rate of endogenous glucose production (EGP).
Targeting pyruvate carboxylase reduces gluconeogenesis and adiposity and improves insulin resistance
Autor:
Bryce K. Perler, Michael J. Jurczak, Fitsum Guebre-Egziabher, Vara Prasad Manchem, Kitt Falk Petersen, Michelle Puchowicz, Ioana Fat, Sara A. Beddow, Jennifer L. Cantley, Varman T. Samuel, Sachin Majumdar, Christopher D. Still, Blas A. Guigni, Daniel F. Vatner, Gerald I. Shulman, Mario Kahn, Glenn S. Gerhard, Naoki Kumashiro, Sanjay Bhanot, Gary W. Cline, Andreas L. Birkenfeld
Publikováno v:
Diabetes
We measured the mRNA and protein expression of the key gluconeogenic enzymes in human liver biopsy specimens and found that only hepatic pyruvate carboxylase protein levels related strongly with glycemia. We assessed the role of pyruvate carboxylase
Publikováno v:
Stearoyl-CoA Desaturase Genes in Lipid Metabolism ISBN: 9781461479680
Stearoyl-CoA desaturase 2 (SCD2) is one of four highly similar mouse Δ9 desaturases with close identity to the human Δ9 desaturase, hSCD1. SCD2 functions in skin to maintain palmitoleate and oleate in complex lipids and linoleic acid in acylceramid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3cd2bb4e7ea542bbc0848bd9f0ce36aa
https://doi.org/10.1007/978-1-4614-7969-7_10
https://doi.org/10.1007/978-1-4614-7969-7_10