Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Jennifer L. Aron"'
Autor:
Lauriane Galle-Treger, Yuzo Suzuki, Nisheel Patel, Ishwarya Sankaranarayanan, Jennifer L. Aron, Hadi Maazi, Lin Chen, Omid Akbari
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-13 (2016)
Airway hyperreactivity is driven by type 2 cytokines produced by ILC2 and Th2 cells. Here the authors show that an α7-nicotinic receptor agonist (GTS-21) inhibits ILC2 responses and is therapeutic against Alternaria-induced airway hyperreactivity in
Externí odkaz:
https://doaj.org/article/ff5c4e95d75c451a9fe780c3cf581b33
BackgroundThe search for a single, pathogenic genetic variant in a patient suspected to have a monogenic inborn error of immunity (IEI) often reveals a multitude of rare variants of unknown significance (VUS). Distinguishing which VUS is disease-caus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::117dedbf07d2e1ce4263b4e373391172
https://doi.org/10.1101/2022.06.20.496920
https://doi.org/10.1101/2022.06.20.496920
Autor:
Lin Chen, Jennifer L. Aron, Ishwarya Sankaranarayanan, Hadi Maazi, Nisheel Patel, Yuzo Suzuki, Omid Akbari, Lauriane Galle-Treger
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-13 (2016)
Nature Communications
Nature Communications
Allergic asthma is a complex and chronic inflammatory disorder that is associated with airway hyperreactivity (AHR) and driven by Th2 cytokine secretion. Type 2 innate lymphoid cells (ILC2s) produce large amounts of Th2 cytokines and contribute to th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d04a767df9ecfeba2833b6c7c3691336
https://doaj.org/article/ff5c4e95d75c451a9fe780c3cf581b33
https://doaj.org/article/ff5c4e95d75c451a9fe780c3cf581b33
Autor:
Omid Akbari, Jennifer L. Aron
Publikováno v:
Allergy. 72(8)
Group 2 innate lymphoid cells (ILC2s) are a recently identified group of cells with the potent capability to produce Th2-type cytokines such as interleukin (IL)-5 and IL-13. Several studies suggest that ILC2s play an important role in the development
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90f4371da9092ec9707e5b537d978442
https://pubmed.ncbi.nlm.nih.gov/28160290
https://pubmed.ncbi.nlm.nih.gov/28160290
Publikováno v:
Journal of Thrombosis and Thrombolysis. 37:76-79
The direct thrombin inhibitor dabigatran has been approved for clinical use in many countries for the prevention of stroke and systemic embolism in patients with atrial fibrillation. However, there is no known reversal agent or proven management stra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::424766906d691564e02e8cc05a01c3cb
https://doi.org/10.1007/s11239-013-0913-0
https://doi.org/10.1007/s11239-013-0913-0
Publikováno v:
NeuroImage. 45:976-983
Touch is a fundamental, but complex, element of everyday interaction that impacts one's sensory and affective experience via interoceptive processing. The insular cortex is an integral component of the neural processes involved in interoception, i.e.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53e7a37add2fde04575a2ad7fa140bce
https://doi.org/10.1016/j.neuroimage.2008.12.070
https://doi.org/10.1016/j.neuroimage.2008.12.070
Autor:
Jennifer L. Aron, Martin P. Paulus
Publikováno v:
Addiction. 102:33-43
Aims The purpose of this review is to summarize the neural substrate dysfunctions and disrupted cognitive, affective andexperientialprocessesobservedinmethamphetamineandcocaine-dependentindividuals.Methods Wereviewed all publications in PubMed that c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51c5c80a518fbf328d34286f3c14c958
https://doi.org/10.1111/j.1360-0443.2006.01778.x
https://doi.org/10.1111/j.1360-0443.2006.01778.x
Publikováno v:
Nature Precedings
The experience of time, i.e. the estimation of duration, is fundamental for perception and behavior and, therefore, essential for the survival of the individual organism. Over the last decades, neuroimaging, neurophysiological and clinical neuropsych
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7955583a697653c7431fb604f8d2e749
https://europepmc.org/articles/PMC2933788/
https://europepmc.org/articles/PMC2933788/
Autor:
Melanie E. Davis, John C. Reed, Tiansheng Shen, Guido Marcucci, Timothy Murphy, Joseph Wickham, John C. Byrd, Shinichi Kitada, Michael R. Grever, Andrew P. Mone, Chris Kanakry, Mark R. Parthun, Jennifer L. Aron, David M. Lucas
Publikováno v:
Blood. 102(2)
Depsipeptide is in clinical trials for chronic lymphocytic leukemia (CLL) on the basis of earlier observations demonstrating selective in vitro activity in CLL. We sought to determine the relationship of histone H3 and H4 acetylation, inhibition of h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e023728a16ccbb23933923e2422342d7
https://pubmed.ncbi.nlm.nih.gov/12649137
https://pubmed.ncbi.nlm.nih.gov/12649137
Autor:
John C. Reed, David M. Lucas, Jennifer L. Aron, Ian W. Flinn, Michael Pearson, John C. Byrd, Shinichi Kitada
Publikováno v:
Blood. 99(3)
Rituximab is a chimeric monoclonal antibody directed at CD20 with significant activity in non-Hodgkin lymphoma (NHL) and chronic lymphocytic leukemia (CLL). A variety of pathways of tumor cytotoxicity different from cytotoxic chemotherapy have been p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cd44600aac7f1475e6710ea7ed84ce9
https://pubmed.ncbi.nlm.nih.gov/11807010
https://pubmed.ncbi.nlm.nih.gov/11807010