Zobrazeno 1 - 10
of 121
pro vyhledávání: '"Jennifer L Wilson"'
Publikováno v:
PLoS Computational Biology, Vol 18, Iss 5, p e1009531 (2022)
Schizophrenia is a debilitating psychiatric disorder, leading to both physical and social morbidity. Worldwide 1% of the population is struggling with the disease, with 100,000 new cases annually only in the United States. Despite its importance, the
Externí odkaz:
https://doaj.org/article/8999a3ea27934315a361941094e501fe
Publikováno v:
Cancer Treatment and Research Communications, Vol 29, Iss , Pp 100488- (2021)
Objective: Accurate assessment of lymph node (LN) status is essential for proper staging of resected lung cancer specimens. Here, we assessed pathology-centric interventions to increase the number of peribronchial LNs identified and evaluated in anat
Externí odkaz:
https://doaj.org/article/477460071e0b40f98faf469a6a0fbadf
Publikováno v:
PLoS Computational Biology, Vol 16, Iss 7, p e1007620 (2020)
Myelosuppression is one of the most common and severe adverse events associated with anti-cancer therapies and can be a source of drug attrition. Current mathematical modeling methods for assessing cytopenia risk rely on indirect measurements of drug
Externí odkaz:
https://doaj.org/article/c056a446a8944838b4e947b90834f987
Autor:
Jennifer L Wilson, Rebecca Racz, Tianyun Liu, Oluseyi Adeniyi, Jielin Sun, Anuradha Ramamoorthy, Michael Pacanowski, Russ Altman
Publikováno v:
PLoS Computational Biology, Vol 14, Iss 12, p e1006614 (2018)
Failure to demonstrate efficacy and safety issues are important reasons that drugs do not reach the market. An incomplete understanding of how drugs exert their effects hinders regulatory and pharmaceutical industry projections of a drug's benefits a
Externí odkaz:
https://doaj.org/article/aa1a86d831d5468f9fd1371a1a5ccef1
Preclinical side effect prediction through pathway engineering of protein interaction network models
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology, Vol 13, Iss 7, Pp 1180-1200 (2024)
Abstract Modeling tools aim to predict potential drug side effects, although they suffer from imperfect performance. Specifically, protein–protein interaction models predict drug effects from proteins surrounding drug targets, but they tend to over
Externí odkaz:
https://doaj.org/article/7be32ee0c4174d42806205e7c7bb70d6
Autor:
Ellen R. Bowen, Phillip DiGiacomo, Hannah P. Fraser, Kevin Guttenplan, Benjamin A. H. Smith, Marlene L. Heberling, Laura Vidano, Nigam Shah, Mehrdad Shamloo, Jennifer L. Wilson, Kevin V. Grimes
Publikováno v:
Discover Mental Health, Vol 3, Iss 1, Pp 1-20 (2023)
Abstract Schizophrenia is a debilitating condition necessitating more efficacious therapies. Previous studies suggested that schizophrenia development is associated with aberrant synaptic pruning by glial cells. We pursued an interdisciplinary approa
Externí odkaz:
https://doaj.org/article/3b606447bef44f88a84ab46ba8870c28
Publikováno v:
Thoracic Surgery Clinics. 33:61-69
Robotic tracheobronchoplasty (TBP) is a new surgical approach to treat tracheobronchomalacia (TBM), and is based on open TBP, which has undergone various technical iterations since the 1950s. The robotic approach to TBM may allow for more patients to
Autor:
Muhammad R. Baig, Jennifer L. Wilson, Robert D. Beck, Jennifer A. Lemmer, Anna L. Hernandez, Adeel Meraj, Rebecca N. Tapia, Eric C. Meyer, Jim Mintz, Alan L. Peterson, John D. Roache
Publikováno v:
Journal of Behavioral and Cognitive Therapy. 32:243-253
Autor:
Sidhu P. Gangadharan, Mihir Parikh, Christopher S. Digesu, Juan Ascanio, Adnan Majid, Jennifer L. Wilson, Daniel Ospina-Delgado
Publikováno v:
The Annals of Thoracic Surgery. 114:926-932
Tracheobronchoplasty (TBP) is the gold-standard treatment for severe symptomatic excessive central airway collapse; however outcomes among obese patients are unknown.A retrospective, single-center analysis was conducted on consecutive patients underg
Autor:
Andreas Herrlich, Douglas A. Lauffenburger, Ernest Fraenkel, Venkata S. Sabbisetti, Christina Harrison, Lauren Stopfer, Eirini Kefaloyianni, Jennifer L. Wilson
Figures for network optimization, shEnrich scoring results for all family sizes, the unclustered network, and additional network validation experiments.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::341547140d7c59e2f52ada9915859493
https://doi.org/10.1158/1541-7786.22511320.v1
https://doi.org/10.1158/1541-7786.22511320.v1