Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Jennifer L Leddon"'
Autor:
Gregory K Friedman, Elizabeth A Beierle, George Yancey Gillespie, James M Markert, Alicia M Waters, Chun-Yu Chen, Nicholas L Denton, Kellie B Haworth, Brian Hutzen, Jennifer L Leddon, Keri A Streby, Pin-Yi Wang, Timothy P Cripe
Publikováno v:
Molecular Therapy: Oncolytics, Vol 2, Iss , Pp - (2015)
Oncolytic engineered herpes simplex viruses (HSVs) possess many biologic and functional attributes that support their use in clinical trials in children with solid tumors. Tumor cells, in an effort to escape regulatory mechanisms that would impair th
Externí odkaz:
https://doaj.org/article/208f8509998642acba0b4dae3437f353
Autor:
Timothy P Cripe, Chun-Yu Chen, Nicholas L Denton, Kellie B Haworth, Brian Hutzen, Jennifer L Leddon, Keri A Streby, Pin-Yi Wang, James M Markert, Alicia M Waters, George Yancey Gillespie, Elizabeth A Beierle, Gregory K Friedman
Publikováno v:
Molecular Therapy: Oncolytics, Vol 2, Iss , Pp - (2015)
Progress for improving outcomes in pediatric patients with solid tumors remains slow. In addition, currently available therapies are fraught with numerous side effects, often causing significant life-long morbidity for long-term survivors. The use of
Externí odkaz:
https://doaj.org/article/043d5f96330c4eb88f47cb78076352d8
Autor:
Jennifer L Leddon, Chun-Yu Chen, Mark A Currier, Pin-Yi Wang, Francesca A Jung, Nicholas L Denton, Kevin M Cripe, Kellie B Haworth, Michael A Arnold, Amy C Gross, Timothy D Eubank, William F Goins, Joseph C Glorioso, Justus B Cohen, Paola Grandi, David A Hildeman, Timothy P Cripe
Publikováno v:
Molecular Therapy: Oncolytics, Vol 1, Iss C (2014)
Multiple studies have indicated that in addition to direct oncolysis, virotherapy promotes an antitumor cytotoxic T cell response important for efficacy. To study this phenomenon further, we tested three syngeneic murine sarcoma models that displayed
Externí odkaz:
https://doaj.org/article/bf8e7d0411ef44b882998c44c0e17aa8
Autor:
Andrew W Browne, Jennifer L Leddon, Mark A Currier, Jon P Williams, Jason S Frischer, Margaret H Collins, Chong H Ahn, Timothy P Cripe
Publikováno v:
PLoS ONE, Vol 6, Iss 5, p e19530 (2011)
Cancer biomarkers facilitate screening and early detection but are known for only a few cancer types. We demonstrated the principle of inducing tumors to secrete a serum biomarker using a systemically administered gene delivery vector that targets tu
Externí odkaz:
https://doaj.org/article/912d014b297147e088f0862dc40d129e
Autor:
Jennifer L. Leddon, Shuchi Gulati, Sulsal Haque, Casey Allen, Sarah Palackdharry, Maria Mathews, Nicky Kurtzweil, Muhammed Kashif Riaz, Vinita Takiar, Misako Nagasaka, Yash Patil, Chad Zender, Alice Tang, Brian Cervenka, Julie McGrath, W. Michael Korn, Benjamin H. Hinrichs, Roman Jandarov, Nusrat Harun, Ammar Sukari, Trisha M. Wise-Draper
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research, vol 28, iss 16
Purpose: Locoregional relapse in patients with head and neck squamous cell carcinoma (HNSCC) is common, approaching 50% for some subsites despite multimodality therapy. Salvage surgery is the standard of care, but able to achieve durable control in o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5730e46f7826c241218e4050d6b050e
https://doi.org/10.1158/1078-0432.ccr-21-4554
https://doi.org/10.1158/1078-0432.ccr-21-4554
Autor:
Trisha M. Wise-Draper, Ammar Sukari, Nusrat Harun, Roman Jandarov, Benjamin H. Hinrichs, W. Michael Korn, Julie McGrath, Brian Cervenka, Alice Tang, Chad Zender, Yash Patil, Misako Nagasaka, Vinita Takiar, Muhammed Kashif Riaz, Nicky Kurtzweil, Maria Mathews, Sarah Palackdharry, Casey Allen, Sulsal Haque, Shuchi Gulati, Jennifer L. Leddon
Supplementary Figure from Phase II Trial of Adjuvant Nivolumab Following Salvage Resection in Patients with Recurrent Squamous Cell Carcinoma of the Head and Neck
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b52b0836533bbee1017b8b3d5d45056
https://doi.org/10.1158/1078-0432.22486310
https://doi.org/10.1158/1078-0432.22486310
Autor:
Trisha M. Wise-Draper, Ammar Sukari, Nusrat Harun, Roman Jandarov, Benjamin H. Hinrichs, W. Michael Korn, Julie McGrath, Brian Cervenka, Alice Tang, Chad Zender, Yash Patil, Misako Nagasaka, Vinita Takiar, Muhammed Kashif Riaz, Nicky Kurtzweil, Maria Mathews, Sarah Palackdharry, Casey Allen, Sulsal Haque, Shuchi Gulati, Jennifer L. Leddon
Purpose:Locoregional relapse in patients with head and neck squamous cell carcinoma (HNSCC) is common, approaching 50% for some subsites despite multimodality therapy. Salvage surgery is the standard of care, but able to achieve durable control in on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5d635da54737b2f01c9daaf5f099228
https://doi.org/10.1158/1078-0432.c.6532292.v1
https://doi.org/10.1158/1078-0432.c.6532292.v1
Autor:
Trisha Wise-Draper, Jennifer L. Leddon, Andrew J. Frankart, Arushi Agrawal, Hira Shaikh, Danny Trotier, Logan Roof, Martina Chirra, Roman Jandarov, Timothy Stone, Vinita Takiar
Publikováno v:
The LaryngoscopeBIBLIOGRAPHY. 131(7)
OBJECTIVES/HYPOTHESIS Hypothyroidism is a relatively common complication of head and neck squamous cell carcinoma (HNSCC) treatment. The objective of this study was to determine whether the addition of programmed death ligand-1 (PD-1) or programmed d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae13299fa7719f2158301fe9d5c9ccdc
https://pubmed.ncbi.nlm.nih.gov/33609046
https://pubmed.ncbi.nlm.nih.gov/33609046
Autor:
Vinita Takiar, Roman Jandarov, Li Zhang, Shuchi Gulati, Aubrey Hamilton, Trisha Wise-Draper, Jennifer L. Leddon, Brian Cervenka, Ammar Sukari, Sarah M. Wilson, Casey L. Allen, Alice Tang, Misako Nagasaka, Sulsal Haque, Sarah Palackdharry, Sheena M Lanverman, Chad Zender, Muhammad Kashif Riaz, Yash Patil
Publikováno v:
Journal of Clinical Oncology. 39:6031-6031
6031 Background: Salvage surgery for locally recurrent head and neck squamous cell carcinoma (rHNSCC) results in local control rates of 33-50% but only 20-40% of patients achieve long-term survival necessitating additional therapy (Haque et al., Oral
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::05e44b858991ad641aa801488bbf37d3
https://doi.org/10.1200/jco.2021.39.15_suppl.6031
https://doi.org/10.1200/jco.2021.39.15_suppl.6031
Autor:
Hira Shaikh, Timothy Stone, Vinita Takiar, Arushi Agrawal, Jennifer L. Leddon, Danny Trotier, Trisha Wise-Draper, Roman Jandarov, Martina Chirra, Logan Roof
Publikováno v:
Journal of Clinical Oncology. 38:e18551-e18551
e18551 Background: Treatment for locally advanced head and neck squamous cell carcinoma (HNSCC) involves a combination of surgery, chemotherapy, and radiotherapy (RT). RT for HNSCC is a known risk factor for the development of hypothyroidism. Recentl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e8c316595893e4bbf1f13de81a6530ac
https://doi.org/10.1200/jco.2020.38.15_suppl.e18551
https://doi.org/10.1200/jco.2020.38.15_suppl.e18551