Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Jennifer L Larson-Casey"'
Autor:
Jennifer L Larson-Casey, Chao He, Pulin Che, Meimei Wang, Guoqiang Cai, Young-Il Kim, Mustapha El Hamdaoui, Rafael Grytz, Qiang Ding, A Brent Carter
Publikováno v:
PLoS ONE, Vol 15, Iss 11, p e0241323 (2020)
BackgroundIdiopathic pulmonary fibrosis (IPF) is a chronic, progressive disease with a high morbidity and mortality. Some of the mechanisms of fibrosis development have been described using rodent models; however, the relevance of findings in these a
Externí odkaz:
https://doaj.org/article/e3fb8d8837b248ca9244bbbce1ac8b27
Autor:
Andrea Slusser-Nore, Jennifer L Larson-Casey, Ruowen Zhang, Xu Dong Zhou, Seema Somji, Scott H Garrett, Donald A Sens, Jane R Dunlevy
Publikováno v:
PLoS ONE, Vol 11, Iss 1, p e0147362 (2016)
BACKGROUND:This laboratory previously analyzed the expression of SPARC in the parental UROtsa cells, their arsenite (As(+3)) and cadmium (Cd(+2))-transformed cell lines, and tumor transplants generated from the transformed cells. It was demonstrated
Externí odkaz:
https://doaj.org/article/46abf127960b4047baf36f88b82d99de
Autor:
Jennifer L. Larson-Casey, Shanrun Liu, Jennifer M. Pyles, Suzanne E. Lapi, Komal Saleem, Veena B. Antony, Manuel Lora Gonzalez, David K. Crossman, A. Brent Carter
Publikováno v:
JCI Insight, Vol 8, Iss 9 (2023)
Emerging data indicate an association between environmental heavy metal exposure and lung disease, including lower respiratory tract infections (LRTIs). Here, we show by single-cell RNA sequencing an increase in Pparg gene expression in lung macropha
Externí odkaz:
https://doaj.org/article/947822a27e1045b1b6d20a914f2e5074
Autor:
Stephanie B. Wall, Rui Li, Brittany Butler, Ashley R. Burg, Hubert M. Tse, Jennifer L. Larson-Casey, A. Brent Carter, Clyde J. Wright, Lynette K. Rogers, Trent E. Tipple
Publikováno v:
Antioxidants, Vol 10, Iss 5, p 632 (2021)
Background: Alveolar macrophages (AMs) are resident inflammatory cells in the lung that serve as early sentinels of infection or injury. We have identified thioredoxin reductase 1 inhibition by gold compounds increases activation of nuclear factor er
Externí odkaz:
https://doaj.org/article/29d7bf6060744e24a2b5c48a3154c5d8
Autor:
Jyotsana Pandey, Jennifer L. Larson-Casey, Mallikarjun H. Patil, Rutwij Joshi, Chun-sun Jiang, Yong Zhou, Chao He, A. Brent Carter
Publikováno v:
Journal of Biological Chemistry. 299:104695
Autor:
Sunad Rangarajan, Morgan L. Locy, Diptiman Chanda, Ashish Kurundkar, Deepali Kurundkar, Jennifer L. Larson‐Casey, Pilar Londono, Rushita A. Bagchi, Brian Deskin, Hanan Elajaili, Eva S. Nozik, Jessy S. Deshane, Jaroslaw W. Zmijewski, Oliver Eickelberg, Victor J. Thannickal
Publikováno v:
Aging cell. 21(9)
Mitochondrial dysfunction has been associated with age-related diseases, including idiopathic pulmonary fibrosis (IPF). We provide evidence that implicates chronic elevation of the mitochondrial anion carrier protein, uncoupling protein-2 (UCP2), in
Autor:
Rui-Han Hu, Mustapha El Hamdaoui, Pulin Che, Xueke Zhao, Rafael Grytz, Yiju Cheng, Qiang Ding, Meimei Wang, A. Brent Carter, Jennifer L. Larson-Casey
Publikováno v:
Laboratory Investigation. 101:116-124
Idiopathic pulmonary fibrosis (IPF) is a progressive fibrotic lung disease without effective therapy. Animal models effectively reproducing IPF disease features are needed to study the underlying molecular mechanisms. Tree shrews are genetically, ana
Publikováno v:
J Biol Chem
Heavy metals released into the environment have a significant effect on respiratory health. Lung macrophages are important in mounting an inflammatory response to injury, but they are also involved in repair of injury. Macrophages develop mixed pheno
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 66:250-251
Autor:
A. Brent Carter, Jennifer L. Larson-Casey, Chao He, Guo-Qiang Cai, D. Davis, Qiang Ding, Linlin Gu
Publikováno v:
The FASEB Journal
Idiopathic pulmonary fibrosis (IPF) is a progressive lung disease associated with mitochondrial oxidative stress. Mitochondrial reactive oxygen species (mtROS) are important for cell homeostasis by regulating mitochondrial dynamics. Here, we show tha