Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Jennifer L Fiori"'
Autor:
Hongyu eChen, Bronwen eMartin, Huan eCai, Jennifer L Fiori, Josephine M Egan, Sana eSiddiqui, Stuart eMaudsley
Publikováno v:
Frontiers in Physiology, Vol 3 (2013)
The microscopic image analysis of pancreatic Islet of Langerhans morphology is crucial for the investigation of diabetes and metabolic diseases. Besides the general size of the islet, the percentage and relative position of glucagon-containing alpha-
Externí odkaz:
https://doaj.org/article/91b249b48200485d868330ada26f6da2
Autor:
Zhuo Liu, Wook Kim, Zhike Chen, Yu-Kyong Shin, Olga D Carlson, Jennifer L Fiori, Li Xin, Joshua K Napora, Ryan Short, Juliana O Odetunde, Qizong Lao, Josephine M Egan
Publikováno v:
PLoS ONE, Vol 6, Iss 1, p e16096 (2011)
Type 2 diabetes mellitus (T2DM) results from insulin resistance and β-cell dysfunction, in the setting of hyperglucagonemia. Glucagon is a 29 amino acid peptide hormone, which is secreted from pancreatic α cells: excessively high circulating levels
Externí odkaz:
https://doaj.org/article/5dac0caa7f2b44d7ae2971c61cef844b
Autor:
Erin Goodstein, Yu Kyong Shin, Qing-Rong Liu, Hyekyung Yang, Máire E. Doyle, Sara Santa-Cruz Calvo, Jennifer L. Fiori, Josephine M. Egan, Fred E. Indig, Isabel Gonzalez Mariscal
Publikováno v:
Endocrinology. 159:3331-3339
We and others have reported that taste cells in taste buds express many peptides in common with cells in the gut and islets of Langerhans in the pancreas. Islets and taste bud cells express the hormones glucagon and ghrelin, the same ATP-sensitive po
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a16dafee1c4ffedb6cd3423e2ff57018
https://doi.org/10.1210/en.2018-00534
https://doi.org/10.1210/en.2018-00534
Autor:
Jennifer L. Fiori, Isabel González-Mariscal, Kathleen Farhang, Wook Kim, Mitesh Sanghvi, Susan M. Krzysik-Walker, Olga D. Carlson, Máire E. Doyle, Julie A. Mattison, Kevin J. Pearson, Josephine M. Egan, Rafael de Cabo, Yu Kyong Shin, Ruin Moaddel, Shekhar K. Gadkaree
Publikováno v:
Diabetes
Eating a “Westernized” diet high in fat and sugar leads to weight gain and numerous health problems, including the development of type 2 diabetes mellitus (T2DM). Rodent studies have shown that resveratrol supplementation reduces blood glucose le
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e49e163433f6851253cae9a6e597476e
https://doi.org/10.2337/db13-0266
https://doi.org/10.2337/db13-0266
Autor:
Michael P. O'Connell, Jennifer L. Fiori, Susan M. Krzysik-Walker, Michel Bernier, Mitesh Sanghvi, Ruin Moaddel
Publikováno v:
British Journal of Pharmacology. 164:1026-1040
BACKGROUND AND PURPOSE AM251 is an inverse agonist of the cannabinoid 1 receptor (CB1R) that can exert ‘off-target’ effects in vitro and in CB1R knock-out mice. AM251 is also potent at modulating tumour cell growth, suggesting that growth factor-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::91329b5458c8ad453b9c073116a1af79
https://doi.org/10.1111/j.1476-5381.2011.01384.x
https://doi.org/10.1111/j.1476-5381.2011.01384.x
Autor:
Samudra K. Dissanayake, Amanda D. French, Tura C. Camilli, Mai Xu, Brittany P. Frank, Dennis D. Taub, Stephen M. Hewitt, Michael P. O'Connell, Jennifer L. Fiori, Ashani T. Weeraratna, Michel Bernier, Arnell Carter, Fred E. Indig
Publikováno v:
Oncogene
Tyrosine kinase receptors represent targets of great interest for cancer therapy. Here we demonstrate, for the first time, the importance of the orphan tyrosine kinase receptor, ROR2, in melanoma progression. Using melanoma tissue microarrays we show
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e02c678f45c8ed0471f533e59a1f6e27
https://doi.org/10.1038/onc.2009.305
https://doi.org/10.1038/onc.2009.305
Autor:
Sutapa Kole, Jennifer L. Fiori, Tie Nian Zhu, Michel Bernier, Ashani T. Weeraratna, Christa Morris, Fred E. Indig, Brittany P. Frank, George Elias, Michael P. O'Connell, Joanne H. Hasskamp, Keith S. Hoek
Publikováno v:
Endocrinology. 150:2551-2560
The actin-binding protein filamin A (FLNa) affects the intracellular trafficking of various classes of receptors and has a potential role in oncogenesis. However, it is unclear whether FLNa regulates the signaling capacity and/or down-regulation of t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0736b8733bb72f4b19dd233ced545a0b
https://doi.org/10.1210/en.2008-1344
https://doi.org/10.1210/en.2008-1344
Publikováno v:
International Journal of Medical Sciences, Vol 6, Iss 2, Pp 93-101 (2009)
Cytoplasmic expression of claudin-1 in metastatic melanoma cells correlates to increased migration, and increased secretion of MMP-2 in a PKC dependent manner, whereas claudin-1 nuclear expression is found in benign nevi. Melanoma cells were transfec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doajarticles::4cef5bce70aedf729da2be5049dd5c80
http://www.medsci.org/v06p0093.htm
http://www.medsci.org/v06p0093.htm
Autor:
Eileen M. Shore, Paul C. Billings, Frederick S. Kaplan, Lourdes Serrano de la Peña, Jennifer L. Fiori, Jaimo Ahn
Publikováno v:
Annals of the New York Academy of Sciences. 1068:54-65
Identification of gene mutations in Mendelian disorders is often determined by linkage analysis and positional cloning, an approach that is difficult for fibrodysplasia ossificans progressiva (FOP) due to a low reproductive fitness that results in a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9912554fb699df6f7eb0191660ae7929
https://doi.org/10.1196/annals.1346.008
https://doi.org/10.1196/annals.1346.008
Autor:
Lourdes Serrano de la Peña, Paul C. Billings, Jennifer L. Fiori, Frederick S. Kaplan, Eileen M. Shore
Publikováno v:
Journal of Bone and Mineral Research. 21:902-909
FOP is a disabling disorder in which skeletal muscle is progressively replaced with bone. Lymphocytes, our model system for examining BMP signaling, cannot signal through the canonical Smad pathway unless exogenous Smad1 is supplied, providing a uniq
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::747c2b291b41b3fe8372049bfa3109f1
https://doi.org/10.1359/jbmr.060215
https://doi.org/10.1359/jbmr.060215