Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Jennifer L, Werkheiser"'
Autor:
Donna L. Maier, Smita V. Ghanekar, Charles S. Elmore, Chi-Ming Lee, Min Ding, Jennifer L. Werkheiser, John R. Zysk, Vijay Chhajlani, Jianwei Liu
Publikováno v:
Synapse. 66:315-322
Neuronal nicotinic acetylcholine receptor (nAChR) agonists active at the alpha-7 (α-7) receptor subtype are potential therapeutics for cognitive deficits in schizophrenia, Alzheimer's disease, and other mental disorders. SSR180711, an α-7 selective
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3ccedb9b957284923802ac9c174f5d27
https://doi.org/10.1002/syn.21513
https://doi.org/10.1002/syn.21513
Autor:
Donna L. Maier, Peter Ström, Jennifer L. Werkheiser, Teng Peng, David Tuke, Dan Widzowski, Peter N. Dorff, Charles S. Elmore, Ladislav Mrzljak, Jonas Malmquist, Min Ding, John R. Zysk
Publikováno v:
Synapse. 64:624-633
Positron emission tomography (PET) antagonist ligands such as [(11)C]-raclopride are commonly used to study dopamine D2 receptor (D2) binding of antipsychotics. It has been suggested that agonist radioligands bind preferentially to the high-affinity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33829240f6fb15ebbbbd2391ad4ca2b3
https://doi.org/10.1002/syn.20771
https://doi.org/10.1002/syn.20771
Publikováno v:
Pharmacology Biochemistry and Behavior. 94:410-415
Behavioral assays of the responses to psychomotor stimulants can be used to model certain aspects of CNS pathologies such as psychosis and addiction. However, species-dependent differences in the effects of neuromodulators in these assays can confoun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83d56f91f01aef6d97a4807d5793729f
https://doi.org/10.1016/j.pbb.2009.10.002
https://doi.org/10.1016/j.pbb.2009.10.002
Autor:
Alan Cowan, Sony Chau, Teresa Gomez, Jennifer L. Werkheiser, David Baron, Scott M. Rawls, Craig Henry, Shreya Parekh
Publikováno v:
Pharmacology Biochemistry and Behavior. 92:543-548
Icilin is a cold channel agonist that produces vigorous wet-dog shaking in rats. The shaking is accompanied by an increase in the level of extracellular glutamate in the brain. Hence, we hypothesized that icilin-induced wet-dog shakes are dependent o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aab00f41cc41929ed5abe319f06be2b7
https://doi.org/10.1016/j.pbb.2009.02.005
https://doi.org/10.1016/j.pbb.2009.02.005
Publikováno v:
European Journal of Pharmacology. 578:201-208
Icilin (AG-3-5) is a cold-inducing agent that activates the transient receptor potential channels TRPM8 and TRPA1. Both channels are members of the transient receptor potential (TRP) superfamily of ion channels and are activated by cold. Despite the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18da1a00d69ef2e2f1da52cf003248f3
https://doi.org/10.1016/j.ejphar.2007.09.030
https://doi.org/10.1016/j.ejphar.2007.09.030
Publikováno v:
Neuropharmacology. 52:925-930
Icilin, a cooling compound, produces vigorous wet-dog shakes in rats. We have reported previously that icilin-induced wet-dog shakes are blocked by the kappa opioid receptor agonists, nalfurafine and U50,488H, and that icilin evokes a dose- and time-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11d620cd2a986f1c1c396f0fddaefaa1
https://doi.org/10.1016/j.neuropharm.2006.10.010
https://doi.org/10.1016/j.neuropharm.2006.10.010
Autor:
Tania J. Phillips, Jennifer L. Werkheiser, Ysabel M. Bello, Diana Q. Ho, Elizabeth Pierce, Jasmin Manzoor, Gary L. Grove, Ana P. Lopez, Charles Zerweck
Publikováno v:
Dermatologic Surgery. 26:42-49
Background. A variety of instruments are available that can objectively assess physical parameters of the skin such as strength, firmness, elasticity, hydration, and color, often undetected by clinical assessment. Objective. To assess the physical pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9053901fa91ca471181780cdad198c0c
https://doi.org/10.1046/j.1524-4725.2000.99143.x
https://doi.org/10.1046/j.1524-4725.2000.99143.x
Autor:
Jennifer L. Werkheiser, Maneesha Altekar, Lewis B. Kinter, Jane Stewart, Håkan H. A. S. Andersson, David Brott, Pam Campbell, Patricia Bentley, Russell D. J. Huby
Publikováno v:
Basicclinical pharmacologytoxicology. 111(6)
Centrally acting dopamine agonists (e.g. bromocriptine) and dopamine transport inhibitors (e.g. GBR12909) are known to inhibit oestradiol-induced prolactin release. The capacity of peripherally restricted compounds to do likewise, however, is unknown
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c0131cda3e8d35a51bccaed769ee687
https://pubmed.ncbi.nlm.nih.gov/22742711
https://pubmed.ncbi.nlm.nih.gov/22742711
Autor:
Mark S. Eisman, Jennifer L. Werkheiser, Donna L. Maier, Min Ding, Simon Sydserff, A.J. Williams, Jeffrey S. Smith, S.J. Hubbs, D. Perry, Ladislav Mrzljak
Publikováno v:
Neuroscience. 186
Αlpha-7 neuronal nicotinic receptors (NNRs) are considered targets for cognitive enhancement in schizophrenia and Alzheimer's disease. AZD0328 is an alpha-7 NNR partial agonist that enhances cognition in rodents and nonhuman primates at sub-microgra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::307218f3cde123ff846cf96255a7db66
https://pubmed.ncbi.nlm.nih.gov/21550383
https://pubmed.ncbi.nlm.nih.gov/21550383
Autor:
Min, Ding, Smita, Ghanekar, Charles S, Elmore, John R, Zysk, Jennifer L, Werkheiser, Chi-Ming, Lee, Jianwei, Liu, Vijay, Chhajlani, Donna L, Maier
Publikováno v:
Synapse (New York, N.Y.). 66(4)
Neuronal nicotinic acetylcholine receptor (nAChR) agonists active at the alpha-7 (α-7) receptor subtype are potential therapeutics for cognitive deficits in schizophrenia, Alzheimer's disease, and other mental disorders. SSR180711, an α-7 selective
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6ee9ccaac07baad89a2a35fae002d3c0
https://pubmed.ncbi.nlm.nih.gov/22108786
https://pubmed.ncbi.nlm.nih.gov/22108786