Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Jennifer L, Sargent"'
Autor:
Stephen A Martin, Kenneth A Philbrick, Carmen P Wong, Dawn A Olson, Adam J Branscum, Donald B Jump, Charles K Marik, Jonathan M DenHerder, Jennifer L Sargent, Russell T Turner, Urszula T Iwaniec
Publikováno v:
Endocrine Connections, Vol 8, Iss 11, Pp 1455-1467 (2019)
Mice are a commonly used model to investigate aging-related bone loss but, in contrast to humans, mice exhibit cancellous bone loss prior to skeletal maturity. The mechanisms mediating premature bone loss are not well established. However, our previo
Externí odkaz:
https://doaj.org/article/907570d8c66745c4babfe90e48a0b1f0
Autor:
Michael E Johnson, J Matthew Mahoney, Jaclyn Taroni, Jennifer L Sargent, Eleni Marmarelis, Ming-Ru Wu, John Varga, Monique E Hinchcliff, Michael L Whitfield
Publikováno v:
PLoS ONE, Vol 10, Iss 1, p e0114017 (2015)
Genome-wide expression profiling in systemic sclerosis (SSc) has identified four 'intrinsic' subsets of disease (fibroproliferative, inflammatory, limited, and normal-like), each of which shows deregulation of distinct signaling pathways; however, th
Externí odkaz:
https://doaj.org/article/190c1ebe5bba49acaa2d11bc4f958758
Autor:
Swati Bhattacharyya, Jennifer L Sargent, Pan Du, Simon Lin, Warren G Tourtellotte, Kazuhiko Takehara, Michael L Whitfield, John Varga
Publikováno v:
PLoS ONE, Vol 6, Iss 9, p e23082 (2011)
Transforming growth factor-ß (TGF-ß) signaling is implicated in the pathogenesis of fibrosis in scleroderma or systemic sclerosis (SSc), but the precise mechanisms are poorly understood. The immediate-early gene Egr-1 is an inducible transcription
Externí odkaz:
https://doaj.org/article/69140d2364294017bf50e98e9ca86f9b
Autor:
Jun Wei, Asish K Ghosh, Jennifer L Sargent, Kazuhiro Komura, Minghua Wu, Qi-Quan Huang, Manu Jain, Michael L Whitfield, Carol Feghali-Bostwick, John Varga
Publikováno v:
PLoS ONE, Vol 5, Iss 11, p e13778 (2010)
The nuclear orphan receptor peroxisome proliferator-activated receptor-gamma (PPAR-γ) is expressed in multiple cell types in addition to adipocytes. Upon its activation by natural ligands such as fatty acids and eicosanoids, or by synthetic agonists
Externí odkaz:
https://doaj.org/article/94ff990c8b7b4f87af9aadd5708b3320
Autor:
Ausra Milano, Sarah A Pendergrass, Jennifer L Sargent, Lacy K George, Timothy H McCalmont, M Kari Connolly, Michael L Whitfield
Publikováno v:
PLoS ONE, Vol 3, Iss 7, p e2696 (2008)
Scleroderma is a clinically heterogeneous disease with a complex phenotype. The disease is characterized by vascular dysfunction, tissue fibrosis, internal organ dysfunction, and immune dysfunction resulting in autoantibody production.We analyzed the
Externí odkaz:
https://doaj.org/article/41b03d1e5e6e4fbb923fcde24be15ee7
Autor:
Ausra Milano, Sarah A. Pendergrass, Jennifer L. Sargent, Lacy K. George, Timothy H. McCalmont, M. Kari Connolly, Michael L. Whitfield
Publikováno v:
PLoS ONE, Vol 3, Iss 10 (2008)
Externí odkaz:
https://doaj.org/article/5f7c140cc70a4a228a4f25136c2e84eb
Autor:
Kenneth A. Philbrick, Stephen A. Martin, Carmen P. Wong, Jonathan M DenHerder, Charles K Marik, Donald B. Jump, Adam J. Branscum, Dawn A. Olson, Urszula T. Iwaniec, Russell T. Turner, Jennifer L Sargent
Publikováno v:
Endocrine Connections
Endocrine Connections, Vol 8, Iss 11, Pp 1455-1467 (2019)
Endocrine Connections, Vol 8, Iss 11, Pp 1455-1467 (2019)
Mice are a commonly used model to investigate aging-related bone loss but, in contrast to humans, mice exhibit cancellous bone loss prior to skeletal maturity. The mechanisms mediating premature bone loss are not well established. However, our previo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e87f33b9e0140135c88c9e697bc6e32f
https://pubmed.ncbi.nlm.nih.gov/31590144
https://pubmed.ncbi.nlm.nih.gov/31590144
Autor:
Robert Lafyatis, Stephen H. Clark, Chelsea M. Burgwin, Minghua Wu, Carol M. Artlett, Adam Harris, Elizabeth P. Blankenhorn, Matthew B. Greenblatt, Kristen B. Long, John Varga, Jun Wei, Zhenghui Li, Michael L. Whitfield, Jennifer L. Sargent, Antonios O. Aliprantis, Jaclyn N. Taroni, Raphael Lemaire
Publikováno v:
Arthritis & Rheumatology. 68:2003-2015
Objective Understanding the pathogenesis of systemic sclerosis (SSc) is confounded by considerable disease heterogeneity. Animal models of SSc that recapitulate distinct subsets of disease at the molecular level have not been delineated. We applied i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d57ab25f07200f424d9ed78008463b29
https://doi.org/10.1002/art.39658
https://doi.org/10.1002/art.39658
Autor:
Clifford J. Rosen, Adam J. Branscum, Kenneth A. Philbrick, Jennifer L Sargent, Russell T. Turner, Carmen P. Wong, Dawn A. Olson, J L Gordon, Arianna M. Kahler-Quesada, V E DeMambro, Urszula T. Iwaniec
Publikováno v:
Osteoporosis International. 27:3091-3101
Room temperature housing (22 °C) results in premature cancellous bone loss in female mice. The bone loss was prevented by housing mice at thermoneutral temperature (32 °C). Thermogenesis differs markedly between mice and humans and mild cold stress
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::033248ab27c6e53787184c74d169d180
https://doi.org/10.1007/s00198-016-3634-3
https://doi.org/10.1007/s00198-016-3634-3
Autor:
Johnathan M, DenHerder, Ralph L, Reed, Jennifer L, Sargent, Gerd, Bobe, Jan F, Stevens, Helen E, Diggs
Publikováno v:
Journal of the American Association for Laboratory Animal Science : JAALAS. 56(4)
Buprenorphine is a partial μ-opioid agonist used for analgesia. Due to the small size of laboratory rodents, buprenorphine HCl is typically diluted 10- or 20-fold with a sterile diluent, such as saline, for accurate dosing. Protocols for preparing a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f1ff6103e482f41e9b490bde12c329d1
https://pubmed.ncbi.nlm.nih.gov/28724496
https://pubmed.ncbi.nlm.nih.gov/28724496