Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Jennifer L, Leight"'
Autor:
Priya H. Dedhia, Hemamylammal Sivakumar, Marco A. Rodriguez, Kylie G. Nairon, Joshua M. Zent, Xuguang Zheng, Katie Jones, Liudmila V. Popova, Jennifer L. Leight, Aleksander Skardal
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract Adrenocortical carcinoma (ACC) has a poor prognosis, and no new drugs have been identified in decades. The absence of drug development can partly be attributed to a lack of preclinical models. Both animal models and 2D cell cultures of ACC f
Externí odkaz:
https://doaj.org/article/b1b85de5b9c44c18b6df603e0e5919b5
Publikováno v:
iScience, Vol 25, Iss 7, Pp 104645- (2022)
Summary: Primary tumors secrete large quantities of cytokines and exosomes into the bloodstream, which are uptaken at downstream sites and induce a pro-fibrotic, pro-inflammatory premetastatic niche. Niche development is associated with later increas
Externí odkaz:
https://doaj.org/article/241cba1c022542f79a57b16e333d0223
Autor:
Clarissa Wormsbaecher, Andrea R. Hindman, Alex Avendano, Marcos Cortes-Medina, Caitlin E. Jones, Andrew Bushman, Lotanna Onua, Claire E. Kovalchin, Alina R. Murphy, Hannah L. Helber, Ali Shapiro, Kyle Voytovitch, Xingyan Kuang, Renan Aguilar-Valenzuela, Jennifer L. Leight, Jonathan W. Song, Craig J. Burd
Publikováno v:
Breast Cancer Research, Vol 22, Iss 1, Pp 1-12 (2020)
Abstract Background In utero endocrine disruption is linked to increased risk of breast cancer later in life. Despite numerous studies establishing this linkage, the long-term molecular changes that predispose mammary cells to carcinogenic transforma
Externí odkaz:
https://doaj.org/article/06289fcf953349bf8b69644304328452
Autor:
Caitlin E. Jones, Anisha M. Hammer, YouJin Cho, Gina M. Sizemore, Edna Cukierman, Lisa D. Yee, Samir N. Ghadiali, Michael C. Ostrowski, Jennifer L. Leight
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 21, Iss 1, Pp 132-145 (2019)
The organization of the extracellular matrix has a profound impact on cancer development and progression. The matrix becomes aligned throughout tumor progression, providing “highways” for tumor cell invasion. Aligned matrix is associated with bre
Externí odkaz:
https://doaj.org/article/fb890cfa8be04e6385066d38ace09c7d
Autor:
Caitlin E Jones, Joe T Sharick, Sheila E Colbert, Vasudha C Shukla, Joshua M Zent, Michael C Ostrowski, Samir N Ghadiali, Steven T Sizemore, Jennifer L Leight
Publikováno v:
PLoS ONE, Vol 16, Iss 2, p e0245653 (2021)
Collagen deposition contributes to both high mammographic density and breast cancer progression. Low stromal PTEN expression has been observed in as many as half of breast tumors and is associated with increases in collagen deposition, however the me
Externí odkaz:
https://doaj.org/article/9f9da990094543c491980f3fcf8a6c82
Autor:
Sayumi Tahara, Fernanda Costas C. de Faria, Patricia Sarchet, Federica Calore, Joe Sharick, Jennifer L. Leight, Lucia Casadei, Raphael E. Pollock
Publikováno v:
Human Cell. 36:1081-1089
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::354668d2ef5eda78786081db5ca3dd31
https://doi.org/10.1007/s13577-023-00865-y
https://doi.org/10.1007/s13577-023-00865-y
Publikováno v:
BioTechniques, Vol 64, Iss 5, Pp 203-210 (2018)
Current zymographic techniques detect only a subset of known proteases due to the limited number of native proteins that have been optimized for incorporation into polyacrylamide gels. To address this limitation, we have developed a technique to cova
Externí odkaz:
https://doaj.org/article/582f295d74b943ca8958992373e1c299
Autor:
Caitlin E. Jones, Joe T. Sharick, Steven T. Sizemore, Edna Cukierman, Anne Marie Strohecker, Jennifer L. Leight
Publikováno v:
Cancer Res Commun
Extracellular matrix (ECM) alignment contributes to metastasis in a number of cancers and is a known prognostic stromal factor; however, the mechanisms controlling matrix organization remain unclear. Cancer-associated fibroblasts (CAF) play a critica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e19fe1b401d9f4dcf162758322d1d313
https://doi.org/10.1158/2767-9764.crc-22-0157
https://doi.org/10.1158/2767-9764.crc-22-0157
Publikováno v:
Journal of Biomedical Materials Research Part A. 111:389-403
Self-assembling peptide (SAP) hydrogels provide a fibrous microenvironment to cells while also giving users control of biochemical and mechanical cues. Previously, biochemical cues were introduced by physically mixing them with SAPs prior to hydrogel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ad56afbc94ff86f256d1095f47e349b
https://doi.org/10.1002/jbm.a.37460
https://doi.org/10.1002/jbm.a.37460
Autor:
Jennifer L. Leight, Anne Marie Strohecker, Edna Cukierman, Steven T. Sizemore, Joe T. Sharick, Caitlin E. Jones
Figure S1, S2, S3, Table S1 and S2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::470a2199c9615c25a9055293c1b0d24a
https://doi.org/10.1158/2767-9764.22546143.v1
https://doi.org/10.1158/2767-9764.22546143.v1
