Zobrazeno 1 - 10
of 162
pro vyhledávání: '"Jennifer L, Gommerman"'
Publikováno v:
Frontiers in Immunology, Vol 14 (2024)
Externí odkaz:
https://doaj.org/article/c5978dfbb8c44cfa9a2b5d529ec3ae43
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
The IL-10/IL-10 receptor (IL-10R) axis plays an important role in attenuating neuroinflammation in animal models of Multiple Sclerosis (MS) and increased IL-10 has been associated with a positive response to MS disease modifying therapy. Because envi
Externí odkaz:
https://doaj.org/article/8cac6e84c1334f8399c5fe73f58a501d
Autor:
Stefan Baral, Arnav Agarwal, Sharmistha Mishra, Mario Ostrowski, Michael Brown, Lucie Richard, Stephen W Hwang, Rosane Nisenbaum, Ruby Sniderman, Allison McGeer, Cilia Mejia-Lancheros, Michael Liu, Anne-Claude Gingras, Suzanne Stewart, Irfan Dhalla, Jennifer L Gommerman, Cheryl Pedersen, Olivia Spandier, Jesse I R Jenkinson, Alainna J Jamal, Mikaela Gabriel, Joe Hester
Publikováno v:
BMJ Open, Vol 12, Iss 8 (2022)
Introduction Initial reports suggest people experiencing homelessness (PEH) are at high risk for SARS-CoV-2 infection and associated morbidity and mortality. However, there have been few longitudinal evaluations of the spread and impact of COVID-19 a
Externí odkaz:
https://doaj.org/article/9141e11d182141fc8c64b522fcd99595
Autor:
Michelle Zuo, Naomi M. Fettig, Louis-Philippe Bernier, Elisabeth Pössnecker, Shoshana Spring, Annie Pu, Xianjie I. Ma, Dennis S.W. Lee, Lesley A. Ward, Anshu Sharma, Jens Kuhle, John G. Sled, Anne-Katrin Pröbstel, Brian A. MacVicar, Lisa C. Osborne, Jennifer L. Gommerman, Valeria Ramaglia
Publikováno v:
JCI Insight, Vol 7, Iss 12 (2022)
People living with multiple sclerosis (MS) experience episodic CNS white matter lesions instigated by autoreactive T cells. With age, patients with MS show evidence of gray matter demyelination and experience devastating nonremitting symptomology. Wh
Externí odkaz:
https://doaj.org/article/3179dda5d85f4c3d98777afc0ce6961d
Autor:
Elissa G. Currie, Bryan Coburn, Elisa A. Porfilio, Ping Lam, Olga L. Rojas, Jan Novak, Stuart Yang, Raad B. Chowdhury, Lesley A. Ward, Pauline W. Wang, Khashayar Khaleghi, James An, Sarah Q. Crome, Michelle A. Hladunewich, Sean J. Barbour, Daniel C. Cattran, Rulan S. Parekh, Christoph Licht, Rohan John, Rupert Kaul, Kenneth Croitoru, Scott D. Gray-Owen, David S. Guttman, Jennifer L. Gommerman, Heather N. Reich
Publikováno v:
JCI Insight, Vol 7, Iss 5 (2022)
IgA nephropathy (IgAN) is a leading cause of kidney failure, yet little is known about the immunopathogenesis of this disease. IgAN is characterized by deposition of IgA in the kidney glomeruli, but the source and stimulus for IgA production are not
Externí odkaz:
https://doaj.org/article/594e642df71840fcba72985a2ef82850
Autor:
Shanzeh M. Ahmed, Nina L. Fransen, Hanane Touil, Iliana Michailidou, Inge Huitinga, Jennifer L. Gommerman, Amit Bar-Or, Valeria Ramaglia
Publikováno v:
JCI Insight, Vol 7, Iss 5 (2022)
Subpial cortical demyelination is an important component of multiple sclerosis (MS) pathology contributing to disease progression, yet mechanism(s) underlying its development remain unclear. Compartmentalized inflammation involving the meninges may d
Externí odkaz:
https://doaj.org/article/df6130b85b53448ba53c213de9c6265e
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Although anatomically distant from the central nervous system (CNS), gut-derived signals can dynamically regulate both peripheral immune cells and CNS-resident glial cells to modulate disease. Recent discoveries of specific microbial taxa and microbi
Externí odkaz:
https://doaj.org/article/181b273c03a748ae8a7ec3a5329d2aa5
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 14 (2021)
The last 15 years have seen an explosion of new findings on the role of complement, a major arm of the immune system, in the central nervous system (CNS) compartment including contributions to cell migration, elimination of synapse during development
Externí odkaz:
https://doaj.org/article/ea8f63bc2e1141cfb6993cd93cd68c83
Autor:
Julia K. Copeland, Gary Chao, Shelley Vanderhout, Erica Acton, Pauline W. Wang, Eric I. Benchimol, Ahmed El-Sohemy, Ken Croitoru, Jennifer L. Gommerman, David S. Guttman, the GEMINI Research Team
Publikováno v:
Gut Microbes, Vol 13, Iss 1 (2021)
South Asian (SA) Canadian immigrants have a higher risk of developing certain immune-mediated inflammatory diseases compared to non-migrant SAs. We sought to investigate the effect of migration on the gut metagenome and to identify microbiological as
Externí odkaz:
https://doaj.org/article/66e834fd67114100bce31b9a9d457274
Autor:
Kento T. Abe, Zhijie Li, Reuben Samson, Payman Samavarchi-Tehrani, Emelissa J. Valcourt, Heidi Wood, Patrick Budylowski, Alan P. Dupuis II, Roxie C. Girardin, Bhavisha Rathod, Jenny H. Wang, Miriam Barrios-Rodiles, Karen Colwill, Allison J. McGeer, Samira Mubareka, Jennifer L. Gommerman, Yves Durocher, Mario Ostrowski, Kathleen A. McDonough, Michael A. Drebot, Steven J. Drews, James M. Rini, Anne-Claude Gingras
Publikováno v:
JCI Insight, Vol 5, Iss 19 (2020)
Most of the patients infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) mount a humoral immune response to the virus within a few weeks of infection, but the duration of this response and how it correlates with clinical outcom
Externí odkaz:
https://doaj.org/article/ad2b246270df4becb301a339c8a9e81c