Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Jennifer L, Brogdon"'
Autor:
Lisa Davis, Nathan Riccitelli, Nancy Valencia, Irene L. Ch’en, Shabnam Tangri, Jennifer L. Brogdon, Creton Kalfoglou, Karen Thudium Mueller, Reinhold Pollner
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 20, Iss , Pp 535-541 (2021)
Chimeric antigen receptor (CAR)-T cell therapies reprogram T cells to engage and eliminate cancer cells. Patients’ T cells are transduced in vitro using lentiviral or retroviral vectors containing a CAR transgene. Following infusion, CAR-T cells ex
Externí odkaz:
https://doaj.org/article/2b681f0aeb284e3f903d79b38dc6b465
Autor:
Alfred L. Garfall, Adam D. Cohen, Sandra P. Susanibar-Adaniya, Wei-Ting Hwang, Dan T. Vogl, Adam J. Waxman, Simon F. Lacey, Vanessa E. Gonzalez, Joseph A. Fraietta, Minnal Gupta, Irina Kulikovskaya, Lifeng Tian, Fang Chen, Natalka Koterba, Robert L. Bartoszek, Margaret Patchin, Rong Xu, Gabriela Plesa, Don L. Siegel, Andrea Brennan, Anne Marie Nelson, Regina Ferthio, Angela Cosey, Kim-Marie Shea, Rachel Leskowitz, Megan Four, Wesley V. Wilson, Fei Miao, Eric Lancaster, Beatriz M. Carreno, Gerald P. Linette, Elizabeth O. Hexner, Regina M. Young, Dexiu Bu, Keith G. Mansfield, Jennifer L. Brogdon, Carl H. June, Michael C. Milone, Edward A. Stadtmauer
Publikováno v:
Blood Cancer Discovery. 4:118-133
We conducted a phase I clinical trial of anti-BCMA chimeric antigen receptor T cells (CART-BCMA) with or without anti-CD19 CAR T cells (huCART19) in multiple myeloma (MM) patients responding to third- or later-line therapy (phase A, N = 10) or high-r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af15a4e58dc3d2eade0573800002170e
https://doi.org/10.1158/2643-3230.bcd-22-0074
https://doi.org/10.1158/2643-3230.bcd-22-0074
Autor:
Edward A. Stadtmauer, Michael C. Milone, Carl H. June, Jennifer L. Brogdon, Keith G. Mansfield, Dexiu Bu, Regina M. Young, Elizabeth O. Hexner, Gerald P. Linette, Beatriz M. Carreno, Eric Lancaster, Fei Miao, Wesley V. Wilson, Megan Four, Rachel Leskowitz, Kim-Marie Shea, Angela Cosey, Regina Ferthio, Anne Marie Nelson, Andrea Brennan, Don L. Siegel, Gabriela Plesa, Rong Xu, Margaret Patchin, Robert L. Bartoszek, Natalka Koterba, Fang Chen, Lifeng Tian, Irina Kulikovskaya, Minnal Gupta, Joseph A. Fraietta, Vanessa E. Gonzalez, Simon F. Lacey, Adam J. Waxman, Dan T. Vogl, Wei-Ting Hwang, Sandra P. Susanibar-Adaniya, Adam D. Cohen, Alfred L. Garfall
Supplemental tables: (1) Subject characteristics. (2) Cytogenetic profiles and high-risk features. (3) Prior treatment exposures and refractoriness. (4) CAR T cell product characteristics. (5) Products that did not meet target dose. (6) Adverse event
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a41bd0d88d5d4c7b561e5825c554cb6
https://doi.org/10.1158/2643-3230.22546220
https://doi.org/10.1158/2643-3230.22546220
Autor:
Edward A. Stadtmauer, Michael C. Milone, Carl H. June, Jennifer L. Brogdon, Keith G. Mansfield, Dexiu Bu, Regina M. Young, Elizabeth O. Hexner, Gerald P. Linette, Beatriz M. Carreno, Eric Lancaster, Fei Miao, Wesley V. Wilson, Megan Four, Rachel Leskowitz, Kim-Marie Shea, Angela Cosey, Regina Ferthio, Anne Marie Nelson, Andrea Brennan, Don L. Siegel, Gabriela Plesa, Rong Xu, Margaret Patchin, Robert L. Bartoszek, Natalka Koterba, Fang Chen, Lifeng Tian, Irina Kulikovskaya, Minnal Gupta, Joseph A. Fraietta, Vanessa E. Gonzalez, Simon F. Lacey, Adam J. Waxman, Dan T. Vogl, Wei-Ting Hwang, Sandra P. Susanibar-Adaniya, Adam D. Cohen, Alfred L. Garfall
We conducted a phase I clinical trial of anti-BCMA chimeric antigen receptor T cells (CART-BCMA) with or without anti-CD19 CAR T cells (huCART19) in multiple myeloma (MM) patients responding to third- or later-line therapy (phase A, N = 10) or high-r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80421cf85e910d57e6c55056f662dc98
https://doi.org/10.1158/2643-3230.c.6551123.v1
https://doi.org/10.1158/2643-3230.c.6551123.v1
Autor:
Stephen J. Bagley, Zev A. Binder, Arati S. Desai, Maclean P. Nasrallah, Eileen Maloney, Steven Brem, Robert Lustig, Goldie Kurtz, Michelle Alonso-Basanta, Suyash Mohan, Wei-Ting Hwang, Oliver Y. Tang, Meghan Logun, Meghna Bhattacharyya, Kelly Markowitz, Devora Delman, Amy Marshall, Cecile Alanio, Gregory L. Beatty, Jennifer L. Brogdon, Elizabeth Hexner, Donald M. O'Rourke
Treatment efficacy with chimeric antigen receptor (CAR) T cell therapy in glioblastoma (GBM) is undermined by an immunosuppressive tumor microenvironment (TME). We previously showed that CAR T cell therapy targeting epidermal growth factor receptor v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::91a30f0fa5828a2c7ff7e2eb9c340b21
https://doi.org/10.21203/rs.3.rs-2742648/v1
https://doi.org/10.21203/rs.3.rs-2742648/v1
Autor:
J. Joseph Melenhorst, Gregory M. Chen, Meng Wang, David L. Porter, Changya Chen, McKensie A. Collins, Peng Gao, Shovik Bandyopadhyay, Hongxing Sun, Ziran Zhao, Stefan Lundh, Iulian Pruteanu-Malinici, Christopher L. Nobles, Sayantan Maji, Noelle V. Frey, Saar I. Gill, Alison W. Loren, Lifeng Tian, Irina Kulikovskaya, Minnal Gupta, David E. Ambrose, Megan M. Davis, Joseph A. Fraietta, Jennifer L. Brogdon, Regina M. Young, Anne Chew, Bruce L. Levine, Donald L. Siegel, Cécile Alanio, E. John Wherry, Frederic D. Bushman, Simon F. Lacey, Kai Tan, Carl H. June
Publikováno v:
Nature. 602:503-509
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5eae92a42be329dd0e4c7cfaa15f42a8
https://doi.org/10.1038/s41586-021-04390-6
https://doi.org/10.1038/s41586-021-04390-6
Autor:
Regina M. Myers, Amanda M. DiNofia, Yimei Li, Caroline Diorio, Richard Aplenc, Diane Baniewicz, Jennifer L Brogdon, Colleen Callahan, Boris Engels, Joseph A. Fraietta, Vanessa Gonzalez, Emma Iannone, Allison Barz Leahy, Hongyan Liu, Susan E. McClory, Susan R. Rheingold, Laura Shinehouse, Gerald Wertheim, Lisa Wray, Noelle V. Frey, Shannon L. Maude, Stephan A. Grupp
Publikováno v:
Blood. 140:2376-2377
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d62fe91365dd978329b4b72da12fdbae
https://doi.org/10.1182/blood-2022-168139
https://doi.org/10.1182/blood-2022-168139
Autor:
Saar Gill, Vanessa Vides, Noelle V. Frey, Elizabeth O. Hexner, Susan Metzger, Megan O'Brien, Wei-Ting Hwang, Jennifer L. Brogdon, Megan M. Davis, Joseph A. Fraietta, Avery L. Gaymon, Whitney L. Gladney, Simon F. Lacey, Anne Lamontagne, Anthony R. Mato, Marcela V. Maus, J. Joseph Melenhorst, Edward Pequignot, Marco Ruella, Maksim Shestov, John C. Byrd, Stephen J. Schuster, Donald L. Siegel, Bruce L. Levine, Carl H. June, David L. Porter
Publikováno v:
Blood advances. 6(21)
In chronic lymphocytic leukemia (CLL) patients who achieve a complete remission (CR) to anti-CD19 chimeric antigen receptor T cells (CART-19), remissions are remarkably durable. Preclinical data suggesting synergy between CART-19 and the Bruton’s t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8def37648cb5d5a699edfc25ad44fdeb
https://pubmed.ncbi.nlm.nih.gov/35349631
https://pubmed.ncbi.nlm.nih.gov/35349631
Autor:
J. Joseph Melenhorst, Gregory M. Chen, Meng Wang, David L. Porter, Changya Chen, McKensie A. Collins, Peng Gao, Shovik Bandyopadhyay, Hongxing Sun, Ziran Zhao, Stefan Lundh, Iulian Pruteanu-Malinici, Christopher L. Nobles, Sayantan Maji, Noelle V. Frey, Saar I. Gill, Alison W. Loren, Lifeng Tian, Irina Kulikovskaya, Minnal Gupta, David E. Ambrose, Megan M. Davis, Joseph A. Fraietta, Jennifer L. Brogdon, Regina M. Young, Anne Chew, Bruce L. Levine, Donald L. Siegel, Cécile Alanio, E. John Wherry, Frederic D. Bushman, Simon F. Lacey, Kai Tan, Carl H. June
Publikováno v:
Nature. 612:E22-E22
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1793d4b78f14557a923b8b96eaf9fa8a
https://doi.org/10.1038/s41586-022-05376-8
https://doi.org/10.1038/s41586-022-05376-8
Autor:
J Joseph, Melenhorst, Gregory M, Chen, Meng, Wang, David L, Porter, Changya, Chen, McKensie A, Collins, Peng, Gao, Shovik, Bandyopadhyay, Hongxing, Sun, Ziran, Zhao, Stefan, Lundh, Iulian, Pruteanu-Malinici, Christopher L, Nobles, Sayantan, Maji, Noelle V, Frey, Saar I, Gill, Alison W, Loren, Lifeng, Tian, Irina, Kulikovskaya, Minnal, Gupta, David E, Ambrose, Megan M, Davis, Joseph A, Fraietta, Jennifer L, Brogdon, Regina M, Young, Anne, Chew, Bruce L, Levine, Donald L, Siegel, Cécile, Alanio, E John, Wherry, Frederic D, Bushman, Simon F, Lacey, Kai, Tan, Carl H, June
Publikováno v:
Nature. 602(7897)
The adoptive transfer of T lymphocytes reprogrammed to target tumour cells has demonstrated potential for treatment of various cancers
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::06b0e9624ef1737ea81ae7c99f13ec3f
https://pubmed.ncbi.nlm.nih.gov/36477542
https://pubmed.ncbi.nlm.nih.gov/36477542