Zobrazeno 1 - 10
of 69
pro vyhledávání: '"Jennifer K. Spinler"'
Autor:
Melinda A. Engevik, Heather A. Danhof, Anne Hall, Kristen A. Engevik, Thomas D. Horvath, Sigmund J. Haidacher, Kathleen M. Hoch, Bradley T. Endres, Meghna Bajaj, Kevin W. Garey, Robert A. Britton, Jennifer K. Spinler, Anthony M. Haag, James Versalovic
Publikováno v:
BMC Microbiology, Vol 21, Iss 1, Pp 1-26 (2021)
Abstract Background Bifidobacteria are commensal microbes of the mammalian gastrointestinal tract. In this study, we aimed to identify the intestinal colonization mechanisms and key metabolic pathways implemented by Bifidobacterium dentium. Results B
Externí odkaz:
https://doaj.org/article/4b0f1ff8289a499390185793dc45b7e1
Autor:
Thomas D. Horvath, Faith D. Ihekweazu, Sigmund J. Haidacher, Wenly Ruan, Kristen A. Engevik, Robert Fultz, Kathleen M. Hoch, Ruth Ann Luna, Numan Oezguen, Jennifer K. Spinler, Anthony M. Haag, James Versalovic, Melinda A. Engevik
Publikováno v:
iScience, Vol 25, Iss 5, Pp 104158- (2022)
Summary: Gut microbes can synthesize multiple neuro-active metabolites. We profiled neuro-active compounds produced by the gut commensal Bacteroides ovatus in vitro and in vivo by LC-MS/MS. We found that B. ovatus generates acetic acid, propionic aci
Externí odkaz:
https://doaj.org/article/9265eb55b5e3455eacfd6e2f6f4ffdf8
Autor:
Robert Fultz, Taylor Ticer, Faith D. Ihekweazu, Thomas D. Horvath, Sigmund J. Haidacher, Kathleen M. Hoch, Meghna Bajaj, Jennifer K. Spinler, Anthony M. Haag, Shelly A. Buffington, Melinda A. Engevik
Publikováno v:
Frontiers in Microbiology, Vol 12 (2021)
Background: Bacteroidetes are the most common bacterial phylum in the mammalian intestine and the effects of several Bacteroides spp. on multiple facets of host physiology have been previously described. Of the Bacteroides spp., Bacteroides ovatus ha
Externí odkaz:
https://doaj.org/article/3f81ecd7e8bc48e2bb3e0901f01bfe38
Autor:
Melinda A. Engevik, Heather A. Danhof, Wenly Ruan, Amy C. Engevik, Alexandra L. Chang-Graham, Kristen A. Engevik, Zhongcheng Shi, Yanling Zhao, Colleen K. Brand, Evan S. Krystofiak, Susan Venable, Xinli Liu, Kendal D. Hirschi, Joseph M. Hyser, Jennifer K. Spinler, Robert A. Britton, James Versalovic
Publikováno v:
mBio, Vol 12, Iss 2 (2021)
ABSTRACT Multiple studies have implicated microbes in the development of inflammation, but the mechanisms remain unknown. Bacteria in the genus Fusobacterium have been identified in the intestinal mucosa of patients with digestive diseases; thus, we
Externí odkaz:
https://doaj.org/article/ebd421ea1ed24b248d975fb71e9bd169
Autor:
Melinda A. Engevik, Beatrice Herrmann, Wenly Ruan, Amy C. Engevik, Kristen A. Engevik, Faith Ihekweazu, Zhongcheng Shi, Berkley Luck, Alexandra L. Chang-Graham, Magdalena Esparza, Susan Venable, Thomas D. Horvath, Sigmund J. Haidacher, Kathleen M. Hoch, Anthony M. Haag, Deborah A. Schady, Joseph M. Hyser, Jennifer K. Spinler, James Versalovic
Publikováno v:
Gut Microbes, Vol 13, Iss 1 (2021)
Endoplasmic reticulum (ER) stress compromises the secretion of MUC2 from goblet cells and has been linked with inflammatory bowel disease (IBD). Although Bifidobacterium can beneficially modulate mucin production, little work has been done investigat
Externí odkaz:
https://doaj.org/article/b547b2a318584a06832bccfb65d0de91
Autor:
Melinda A. Engevik, Heather A. Danhof, Ritu Shrestha, Alexandra L. Chang-Graham, Joseph M. Hyser, Anthony M. Haag, Mahmoud A. Mohammad, Robert A. Britton, James Versalovic, Joseph A. Sorg, Jennifer K. Spinler
Publikováno v:
Gut Microbes, Vol 12, Iss 1 (2020)
Antibiotic resistance is one of the world’s greatest public health challenges and adjunct probiotic therapies are strategies that could lessen this burden. Clostridioides difficile infection (CDI) is a prime example where adjunct probiotic therapie
Externí odkaz:
https://doaj.org/article/548379f0ffcc4fa28d4b96b38d0cd042
Autor:
Berkley Luck, Thomas D. Horvath, Kristen A. Engevik, Wenly Ruan, Sigmund J. Haidacher, Kathleen M. Hoch, Numan Oezguen, Jennifer K. Spinler, Anthony M. Haag, James Versalovic, Melinda A. Engevik
Publikováno v:
Biomolecules, Vol 11, Iss 8, p 1091 (2021)
Background: Accumulating evidence indicates that the gut microbiota can synthesize neurotransmitters as well as impact host-derived neurotransmitter levels. In the past, it has been challenging to decipher which microbes influence neurotransmitters d
Externí odkaz:
https://doaj.org/article/9957884028b544c28ae894be0f90959b
Autor:
Melinda A. Engevik, Christina N. Morra, Daniel Röth, Kristen Engevik, Jennifer K. Spinler, Sridevi Devaraj, Sue E. Crawford, Mary K. Estes, Markus Kalkum, James Versalovic
Publikováno v:
Frontiers in Microbiology, Vol 10 (2019)
Microbial metabolites, including B complex vitamins contribute to diverse aspects of human health. Folate, or vitamin B9, refers to a broad category of biomolecules that include pterin, para-aminobenzoic acid (pABA), and glutamate subunits. Folates a
Externí odkaz:
https://doaj.org/article/4201e249716c4d47b5b83dd605199963
Autor:
Thomas D. Horvath, Sigmund J. Haidacher, Melinda A. Engevik, Berkley Luck, Wenly Ruan, Faith Ihekweazu, Meghna Bajaj, Kathleen M. Hoch, Numan Oezguen, Jennifer K. Spinler, James Versalovic, Anthony M. Haag
Publikováno v:
Nature Protocols. 18:490-529
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8087d42a10a65eb1527551fad24ca834
https://doi.org/10.1038/s41596-022-00767-7
https://doi.org/10.1038/s41596-022-00767-7
Autor:
Sabeen Raza, Ruth Ann Luna, Alamelu Venkatachalam, James Versalovic, Jennifer K. Spinler, Tiana Scott, James J. Dunn, Jessica K. Runge, Santosh Thapa
Publikováno v:
The Journal of Molecular Diagnostics. 24:158-166
Hospital-acquired infections pose significant costly global challenges to patient care. Rapid and sensitive methods to identify potential outbreaks are integral to infection control measures. Whole-genome sequencing (WGS)-based bacterial strain typin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84a3ff5c0f11f3ba5ed8c8d362fc1178
https://doi.org/10.1016/j.jmoldx.2021.10.004
https://doi.org/10.1016/j.jmoldx.2021.10.004