Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Jennifer K. Ondr"'
Autor:
Li-Kun Phng, Sujata Rao, Richard A. Lang, Ivan B. Lobov, Michael Potente, Jennifer K. Ondr, Daniel Nyqvist, Jonathan D. Leslie, Gavin Thurston, Jane Babbage, Holger Gerhardt
Publikováno v:
Dev Cell
SummaryWhen and where to make or break new blood vessel connections is the key to understanding guided vascular patterning. VEGF-A stimulation and Dll4/Notch signaling cooperatively control the number of new connections by regulating endothelial tip
Publikováno v:
The Journal of Immunology. 179:5041-5053
Islet Ag-specific CD4+ T cells receive antigenic stimulation from MHC class II-expressing APCs. Herein, we delineate the direct in vivo necessity for distinct subsets of macrophages and dendritic cells (DC) in type 1 diabetes mellitus of the NOD mous
Autor:
Christine T.N. Pham, Jennifer K. Ondr
Publikováno v:
Journal of Biological Chemistry. 279:27525-27533
Cathepsin W is a member of the papain-like family of cysteine proteases. In this report, we have isolated the cDNA for murine CtsW (mCtsW) from a splenocyte library. The deduced 371-amino-acid sequence shares 68% identity with human CtsW and includes
Publikováno v:
Journal of Phycology. 36:107-117
Aerobic unicellular cyanobacteria temporally separate nitrogen fixation and photosynthetic activity to protect oxygen-sensitive nitrogenase. Diurnal metabolic oscillations in the unicellular diazotroph, Cyanothece sp. str. CGD occurred even when cell
Autor:
Richard A. Lang, Lukas Cajanek, Vitezslav Bryja, Ernest Arenas, Jennifer K. Ondr, Carina Palmberg, Gonçalo Castelo-Branco, J. Carlos Villaescusa, Brandon J. Wainwright, Kyle M. Sousa, Tomas Bergman, Wytske Hofstra
Publikováno v:
The Journal of biological chemistry. 285(10)
Wnts are secreted, lipidated proteins that regulate multiple aspects of brain development, including dopaminergic neuron development. In this study, we perform the first purification and signaling analysis of Wnt2 and define the function of Wnt2 in v
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 176(3)
In type 1 diabetes mellitus (T1DM), T cell-mediated destruction of insulin-producing pancreatic β cells leads to the acute onset of hyperglycemia. The nonobese diabetic mouse model of human T1DM reveals that T cells capable of inducing diabetes can
Autor:
Donald A. Glass, Thomas L. Carroll, Edward E. Morrisey, Masataka Ito, Jennifer K. Ondr, Richard A. Lang, Ivan B. Lobov, Gerard Karsenty, Millan S. Patel, Jefferson E. Vallance, Sujata Rao, Andrew P. McMahon, Weiguo Shu, Savita Kurup
Publikováno v:
Nature. 437(7057)
Macrophages have a critical role in inflammatory and immune responses through their ability to recognize and engulf apoptotic cells. Here we show that macrophages initiate a cell-death programme in target cells by activating the canonical WNT pathway
Publikováno v:
The Journal of Immunology. 178:S234-S235
Islets specific CD4+ T Cells receive instructional signals from antigen bearing MHC class II-expressing antigen presenting cells (APC), yet the influence of APC on autoimmune diabetes remains elusive. Herein we delineate the direct in vivo necessity
Publikováno v:
Clinical Immunology. 123:S18-S19
Autor:
Meghana B. Kamath, Rodney P. DeKoter, Brock L. Schweitzer, Jennifer K. Ondr, Timothy M. Chlon, Isaac B. Houston
Publikováno v:
Blood. 108:1180-1180
PU.1 is an Ets-family transcription factor that is critical for normal hematopoiesis. Knock-out studies of PU.1 demonstrate that it is required for the development of myeloid and lymphoid cells. PU.1 is expressed at graded levels in the immune system