Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Jennifer K. Melbourne"'
Autor:
Jennifer K. Melbourne, Jessica I. Wooden, Erika R. Carlson, Chinchusha Anasooya Shaji, Kimberly Nixon
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 3, p 1603 (2024)
The rates of alcohol use disorder among women are growing, yet little is known about how the female brain is affected by alcohol. The neuroimmune system, and specifically microglia, have been implicated in mediating alcohol neurotoxicity, but most pr
Externí odkaz:
https://doaj.org/article/4e04935418c3464dbc553c45cee63510
Autor:
Jessica I. Wooden, Lauren E. Peacoe, Chinchusha Anasooya Shaji, Jennifer K. Melbourne, Cassie M. Chandler, Michael T. Bardo, Kimberly Nixon
Publikováno v:
Cells, Vol 12, Iss 21, p 2572 (2023)
During adolescence, the brain is highly susceptible to alcohol-induced damage and subsequent neuroimmune responses, effects which may enhance development of an alcohol use disorder (AUD). Neuroimmune reactions are implicated in adolescent alcohol exp
Externí odkaz:
https://doaj.org/article/59e18004e79a4d4590e0c0ac61e66216
Publikováno v:
Frontiers in Psychiatry, Vol 12 (2021)
With advanced understanding of the intricate interplay between the immune and central nervous systems in neurological and neuropsychiatric illness, there is renewed interest in the potential contribution of immune dysregulation to the development and
Externí odkaz:
https://doaj.org/article/6c7f0d89f8064000a6b9bbe07492107d
Autor:
Cherise Rosen, Nev Jones, Eleanor Longden, Kayla A. Chase, Mona Shattell, Jennifer K. Melbourne, Sarah K. Keedy, Rajiv P. Sharma
Publikováno v:
Frontiers in Psychiatry, Vol 8 (2017)
Traumatic life events (TLEs) have been associated with multiple psychiatric diagnoses, including anxiety disorders, major depression, PTSD, and psychosis. To advance our understanding of the complex interactions between forms of adversity as they man
Externí odkaz:
https://doaj.org/article/d78d808c808345d4b74d207ec7ebb289
Autor:
Niyati Sudhalkar, Cherise Rosen, Jennifer K. Melbourne, Mi Rae Park, Kayla A. Chase, Rajiv P. Sharma
Publikováno v:
Non-Coding RNA, Vol 4, Iss 4, p 43 (2018)
Psychosis is associated with chronic immune dysregulation. Many long non-coding RNAs (lncRNAs) display abnormal expression during activation of immune responses, and play a role in heterochromatic regulation of gene promoters. We have measured lncRNA
Externí odkaz:
https://doaj.org/article/63fc2942c43349598c289ee2091b0f0b
Autor:
Hui Peng, Catherine E. Van Doorn, Kimberly Nixon, Michael T. Bardo, Jennifer K. Melbourne, James R. Pauly, Cassie M. Chandler
Publikováno v:
Alcohol Clin Exp Res
Alcohol is one of the most widely used recreational substances worldwide, with drinking frequently initiated during adolescence. The developmental state of the adolescent brain makes it vulnerable to initiating alcohol use, often in high doses, and p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e89125f0ef3f500123cf8497c199429
https://europepmc.org/articles/PMC8793635/
https://europepmc.org/articles/PMC8793635/
Publikováno v:
Clinical and Experimental Immunology. 196:67-75
Summary Epigenetic effects of anti-psychotic medications are poorly understood. We have appropriated a model whereby heterochromatin is established through 24- or 48-h lipopolysaccharide (LPS) treatment, and tested the epigenetic effects of risperido
Publikováno v:
Schizophrenia Research. 197:321-327
Altered immune function is an established finding in psychotic disorders such as schizophrenia and bipolar disorder with psychosis, though its role in their development and progression remains to be understood. Evidence suggests altered JAK-STAT1 pat
Publikováno v:
Progress in molecular biology and translational science. 167
Alcohol use disorder (AUD) is a chronic relapsing disorder with wide-ranging health consequences. Alcohol targets the central nervous system producing neurodegeneration and subsequent cognitive and behavioral deficits, but the mechanisms behind these
Autor:
Kayla A. Chase, Rajiv P. Sharma, Nev Jones, Cherise Rosen, Linda S. Grossman, Jennifer K. Melbourne
Publikováno v:
Consciousness and Cognition. 49:215-226
Understanding alterations in perceptual experiences as a component of the basic symptom structure of psychosis may improve early detection and the identification of subtle shifts that can precede symptom onset or exacerbation. We explored the phenome