Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Jennifer K. Blackburn"'
Publikováno v:
Biology of Sex Differences, Vol 14, Iss 1, Pp 1-11 (2023)
Abstract Background Paraoxonase 2 (PON2) and neuronal uncoupling proteins (UCP4 and UCP5) possess antioxidant, anti-apoptotic activities and minimize accumulation of reactive oxygen species in mitochondria. While age and sex are risk factors for seve
Externí odkaz:
https://doaj.org/article/b957cf2b2e8e451794a39a6ab58f8701
Autor:
Nickolai V Vysokov, John-Paul Silva, Vera G Lelianova, Jason Suckling, John Cassidy, Jennifer K Blackburn, Natalia Yankova, Mustafa BA Djamgoz, Serguei V Kozlov, Alexander G Tonevitsky, Yuri A Ushkaryov
Publikováno v:
eLife, Vol 7 (2018)
A presynaptic adhesion G-protein-coupled receptor, latrophilin-1, and a postsynaptic transmembrane protein, Lasso/teneurin-2, are implicated in trans-synaptic interaction that contributes to synapse formation. Surprisingly, during neuronal developmen
Externí odkaz:
https://doaj.org/article/e3ab38e5ab3145c8b2d8316c81bfd8a3
Publikováno v:
Free Radic Biol Med
Mitochondrial dysfunction and oxidative stress contribute to the neuropathology of neurodegenerative disorders such as Parkinson’s disease (PD). Paraoxonase-2 (PON2) is a mitochondrial protein that mitigates oxidative stress, enhances mitochondrial
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac2fda36db734c56b6db5bd7ddbecc14
https://pubmed.ncbi.nlm.nih.gov/34890766
https://pubmed.ncbi.nlm.nih.gov/34890766
Publikováno v:
Neurochem Int
Paraoxonase-2 (PON2) enhances mitochondria function and protects against oxidative stress. Stimulating its expression has therapeutic potential for diseases where oxidative stress plays a significant role in the pathology, such as Parkinson's disease
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd7e12e68a7f67f88ec2aacf80a8e5bd
https://pubmed.ncbi.nlm.nih.gov/34767873
https://pubmed.ncbi.nlm.nih.gov/34767873
Publikováno v:
Free Radic Biol Med
The development of several neurodegenerative disorders, such as Parkinson's disease, has been linked with decreased mitochondrial performance, leading to oxidative stress as a result of increased production of reactive oxygen species (ROS). Previous
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3637c14efb77225da67bbfb52d29e4d2
https://pubmed.ncbi.nlm.nih.gov/33722626
https://pubmed.ncbi.nlm.nih.gov/33722626
Autor:
Yuri A. Ushkaryov, Ouafa Benlaouer, C Manser, M. Atiqur Rahman, Jennifer K. Blackburn, Jason Suckling, John-Paul Silva
Latrophilin-1 is an Adhesion G protein-coupled receptor, which mediates the effect of α-latrotoxin, causing massive release of neurotransmitters from nerve terminals and endocrine cells. Autoproteolysis cleaves latrophilin-1 into two parts: the extr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13c0605ef5436672ccfd834af7506555
Publikováno v:
Exp Neurol
Paraoxonase-2 regulates reactive oxygen species production in mitochondria. Stimulating its expression has therapeutic potential for diseases where oxidative stress plays a significant role in the pathology. Evidence suggests that the anti-diabetic d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c57379f0c5e34184cb00be082fb9af2
https://doi.org/10.1016/j.expneurol.2020.113234
https://doi.org/10.1016/j.expneurol.2020.113234
Autor:
John H. Cassidy, Yuri A. Ushkaryov, Nickolai Vysokov, Jennifer K. Blackburn, John-Paul Silva, Jason Suckling, Vera G. Lelianova, Natalia Yankova, Serguei V Kozlov, Alexander G. Tonevitsky, Mustafa B. A. Djamgoz
Publikováno v:
eLife, Vol 7 (2018)
eLife
eLife
A presynaptic adhesion G-protein-coupled receptor, latrophilin-1, and a postsynaptic transmembrane protein, Lasso/teneurin-2, are implicated in trans-synaptic interaction that contributes to synapse formation. Surprisingly, during neuronal developmen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4986b89125746641bf5c32de3be3c904
https://kar.kent.ac.uk/69740/11/elife-37935-v1.pdf
https://kar.kent.ac.uk/69740/11/elife-37935-v1.pdf
Autor:
Alexander G. Tonevitsky, Serguei V Kozlov, Natalia Yankova, Yuri A. Ushkaryov, John-Paul Silva, Vera G. Lelianova, Mustafa B.A. Djamgoz, Nickolai Vysokov, Jennifer K. Blackburn, Jason Suckling, John H. Cassidy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c66c15423d37522ec9484abc31f94282
https://doi.org/10.7554/elife.37935.028
https://doi.org/10.7554/elife.37935.028
Autor:
Jennifer K. Blackburn, Yuri A. Ushkaryov, Alexander G. Tonevitsky, Inna M. Yasinska, Michelle D. Garrett, Isabel Gonçalves Silva, Vadim V. Sumbayev, Bernhard F. Gibbs
Publikováno v:
Oncotarget
// Vadim V. Sumbayev 1 , Isabel Goncalves Silva 1 , Jennifer Blackburn 1 , Bernhard F. Gibbs 1 , Inna M. Yasinska 1 , Michelle D. Garrett 2 , Alexander G. Tonevitsky 3 , Yuri A. Ushkaryov 1 1 School of Pharmacy, University of Kent, Chatham, Kent, ME4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cfddd7137262bca4b604af1319bb86e2
https://pubmed.ncbi.nlm.nih.gov/27322212
https://pubmed.ncbi.nlm.nih.gov/27322212