Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Jennifer K Truong"'
Autor:
Jennifer K. Truong, Jianing Li, Qin Li, Kimberly Pachura, Anuradha Rao, Sanjeev Gumber, Claudia Daniela Fuchs, Andrew P. Feranchak, Saul J. Karpen, Michael Trauner, Paul A. Dawson
Publikováno v:
JCI Insight, Vol 8, Iss 6 (2023)
The pronounced choleretic properties of 24-norUrsodeoxycholic acid (norUDCA) to induce bicarbonate-rich bile secretion have been attributed to its ability to undergo cholehepatic shunting. The goal of this study was to identify the mechanisms underly
Externí odkaz:
https://doaj.org/article/e4cbe8bcbe354f94a29a2c7ee0acf8e0
Autor:
Jennifer K. Truong, Ashley L. Bennett, Caroline Klindt, Ajay C. Donepudi, Sudarshan R. Malla, Kimberly J. Pachura, Alex Zaufel, Tarek Moustafa, Paul A. Dawson, Saul J. Karpen
Publikováno v:
Journal of Lipid Research, Vol 63, Iss 9, Pp 100261- (2022)
Cyp2c70 is the liver enzyme in rodents responsible for synthesis of the primary 6-hydroxylated muricholate bile acid (BA) species. Cyp2c70 KO mice are devoid of protective, hydrophilic muricholic acids, leading to a more human-like BA composition and
Externí odkaz:
https://doaj.org/article/c8b1893ec9fd4770aafc4f38f85d3bae
Autor:
Jennifer K. Truong, Ajay Donepudi, Ashley Bennett, Sudarshan Malla, Alex Zaufel, Kimberly Pachura, Dominick Hellen, Tarek Moustafa, Paul Dawson, Saul Karpen
Publikováno v:
The FASEB Journal. 36
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c82a5a4a02c0ef5cc6f537c0ba59e1ed
https://doi.org/10.1096/fasebj.2022.36.s1.r5088
https://doi.org/10.1096/fasebj.2022.36.s1.r5088
Autor:
Khosrow Adeli, Valentin Blanchard, Michael B. Boffa, Mikhail Bogdanov, Laura M. Bond, Andrew J. Brown, Hudson W. Coates, Paul A. Dawson, Fang Ding, William Dowhan, Guangwei Du, Sarah Farr, Eric A. Fisher, Gordon A. Francis, Anthony H. Futerman, Jessica M. Gullett, Joachim Herz, Victoria Higgins, Murray W. Huff, Elina Ikonen, Marlys L. Koschinsky, Kristina Kuhbandner, Richard Lehner, Sarah A. Lewis, Gary F. Lewis, Jun Liu, Zhaojin Liu, Andrea F. Lopez-Clavijo, Roger S. McLeod, Makoto Miyazaki, James M. Ntambi, Vesa M. Olkkonen, Lucas M. O'Neill, Theresa Pohlkamp, Ariel D. Quiroga, Katey J. Rayner, Marilyn D. Resh, Neale D. Ridgway, Charles O. Rock, Katherine M. Schmid, Laura J. Sharpe, Bebiana C. Sousa, Jennifer Taher, Jennifer K. Truong, Michael J.O. Wakelam, Changting Xiao, Hongyuan Yang, Dakai Zhang
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a6f68922a76c48b2c267825a3a988e00
https://doi.org/10.1016/b978-0-12-824048-9.01002-6
https://doi.org/10.1016/b978-0-12-824048-9.01002-6
Autor:
Günter Fauler, John F. Gilmer, Paul A. Dawson, Sandra M. W. van de Wiel, Alex Zaufel, Tarek Moustafa, Lu Yin, Peter Fickert, Jennifer K. Truong, Daphne Chien, Stan F.J. van de Graaf, Xinzhong Dong
Publikováno v:
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE, 1867(8):166153. Elsevier
Biochimica et biophysica acta. Molecular basis of disease
Biochimica et biophysica acta. Molecular basis of disease
IsoBAs, stereoisomers of primary and secondary BAs, are found in feces and plasma of human individuals. BA signaling via the nuclear receptor FXR is crucial for regulation of hepatic and intestinal physiology/pathophysiology. Aim: Investigate the abi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f659f989d335b18dfbf5106c9dd780b
https://pure.amc.nl/en/publications/secondary-isobas-cooperate-with-endogenous-ligands-to-activate-fxr-under-physiological-and-pathological-conditions(79ff6e65-2212-4c72-8711-b6600f0ceed2).html
https://pure.amc.nl/en/publications/secondary-isobas-cooperate-with-endogenous-ligands-to-activate-fxr-under-physiological-and-pathological-conditions(79ff6e65-2212-4c72-8711-b6600f0ceed2).html
Autor:
Ross Fredenburg, Matthew M. Goddeeris, Jennifer K Truong, Effie Tozzo, Dominique Stickens, Robert W. Shine, Eric L. Bell, Peter Dwyer, Lyndsay Olson
Publikováno v:
Mitochondrion. 46:51-58
Duchenne muscular dystrophy (DMD) is a recessive, fatal X-linked disease that is characterized by progressive skeletal muscle wasting due to the absence of dystrophin, which is an a essential protein that bridges the inner cytoskeleton and extra-cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c48a8f8c9081cb3f6797bc8e3393b4c
https://doi.org/10.1016/j.mito.2018.02.006
https://doi.org/10.1016/j.mito.2018.02.006
Autor:
Jennifer K Truong, Gregory M. Cockrell, Evan R. Kantrowitz, Wenyue Guo, Alexis W. Peterson, Yunan Zheng
Publikováno v:
Biochemistry. 52:8036-8047
For nearly 60 years, the ATP activation and the CTP inhibition of Escherichia coli aspartate transcarbamoylase (ATCase) has been the textbook example of allosteric regulation. We present kinetic data and five X-ray structures determined in the absenc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e50368a9fe675a8656b4b1c63a0479a2
https://doi.org/10.1021/bi401205n
https://doi.org/10.1021/bi401205n