Zobrazeno 1 - 10
of 200
pro vyhledávání: '"Jennifer K Richer"'
Autor:
Michelle M Williams, Jessica Christenson, Sabrina Hafeez, Li-Wei Kuo, Lyndsey Crump, Nicole S Spoelstra, Kathleen I O’Neill, Jill E Slansky, Jennifer K Richer
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/ecfd8e22ec824c0497c291b7846eb28c
Autor:
Allison M Porman, Justin T Roberts, Emily D Duncan, Madeline L Chrupcala, Ariel A Levine, Michelle A Kennedy, Michelle M Williams, Jennifer K Richer, Aaron M Johnson
Publikováno v:
PLoS Biology, Vol 20, Iss 11, p e3001885 (2022)
N6-methyladenosine (m6A) modification of RNA regulates normal and cancer biology, but knowledge of its function on long noncoding RNAs (lncRNAs) remains limited. Here, we reveal that m6A regulates the breast cancer-associated human lncRNA HOTAIR. Map
Externí odkaz:
https://doaj.org/article/64ddea15eef444408f11c50b7522ba53
Autor:
Brian F Niemeyer, Janet K Parrish, Nicole S Spoelstra, Teresa Joyal, Jennifer K Richer, Paul Jedlicka
Publikováno v:
PLoS ONE, Vol 10, Iss 1, p e0116895 (2015)
Ewing Sarcoma is an aggressive malignancy of bone and soft tissue affecting children and young adults. Ewing Sarcoma is driven by EWS/Ets fusion oncoproteins, which cause widespread alterations in gene expression in the cell. Dysregulation of recepto
Externí odkaz:
https://doaj.org/article/15e6735ba0884fdd99cfafae0740db86
Publikováno v:
PLoS ONE, Vol 7, Iss 11, p e49987 (2012)
Anoikis is apoptosis initiated upon cell detachment from the native extracellular matrix. Since survival upon detachment from basement membrane is required for metastasis, the ability to resist anoikis contributes to the metastatic potential of breas
Externí odkaz:
https://doaj.org/article/b66ac38e35ee4695873797c718b0ab06
Publikováno v:
American journal of physiology. Cell physiology. 323(6)
Metastatic cancer is difficult to treat and is responsible for the majority of cancer-related deaths. After cancer cells initiate metastasis and successfully seed a distant site, resident cells in the tissue play a key role in determining how metasta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b4d20cb0e33b922470f2b0737b2c2d9
https://pubmed.ncbi.nlm.nih.gov/36252127
https://pubmed.ncbi.nlm.nih.gov/36252127
Publikováno v:
American journal of physiology. Cell physiology. 323(5)
Normal developmental processes, such as those seen during embryonic development and postpartum mammary gland involution, can be reactivated by cancer cells to promote immune suppression, tumor growth, and metastatic spread. In mammalian embryos, pate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::435015a3347e84c4d4a2f10027b379c7
https://pubmed.ncbi.nlm.nih.gov/36189970
https://pubmed.ncbi.nlm.nih.gov/36189970
Autor:
Anthony D. Elias, Nicole S. Spoelstra, Alyse W. Staley, Sharon Sams, Lyndsey S. Crump, Gregory A. Vidal, Virginia F. Borges, Peter Kabos, Jennifer R. Diamond, Elena Shagisultanova, Anosheh Afghahi, Jose Mayordomo, Tessa McSpadden, Gloria Crawford, Angelo D’Alessandro, Kathryn L. Zolman, Adrie van Bokhoven, Yonghua Zhuang, Rosa I. Gallagher, Julia D. Wulfkuhle, Emanuel F. Petricoin III, Dexiang Gao, Jennifer K. Richer
Publikováno v:
npj Breast Cancer. 9
This clinical trial combined fulvestrant with the anti-androgen enzalutamide in women with metastatic ER+/HER2− breast cancer (BC). Eligible patients were women with ECOG 0–2, ER+/HER2− measurable or evaluable metastatic BC. Prior fulvestrant w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9c1d1a78b2af14c30b77fb9d84d37a01
https://doi.org/10.1038/s41523-023-00544-z
https://doi.org/10.1038/s41523-023-00544-z
Autor:
Morag J. Young, Nancy Weigel, Marc Tetel, Carol A. Sartorius, Jennifer K. Richer, Robert H. Oakley, Carol A. Lange, Sean Hartig, Sandra L. Grimm, Peter Fuller, Dean P. Edwards, John Cidlowski, Derek Cain
Publikováno v:
IUPHAR/BPS Guide to Pharmacology CITE. 2023
Steroid hormone receptors (nomenclature as agreed by the NC-IUPHAR Subcommittee on Nuclear Hormone Receptors [75, 218, 3]) are nuclear hormone receptors of the NR3 class, with endogenous agonists that may be divided into 3-hydroxysteroids (estrone an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ebf16bab28044812b32369d76cbf14d0
https://doi.org/10.2218/gtopdb/f98/2023.1
https://doi.org/10.2218/gtopdb/f98/2023.1
Autor:
Jennifer K. Richer, Joel R. Eisner, Anthony Elias, Elaina T. Van Patten, Jordan Reese, G. Devon Trahan, Kenneth L. Jones, Nicole S. Spoelstra, Michelle M. Williams, Kathleen I. O'Neill, Jessica L. Christenson
Single-cell RNAseq of AR expressing MDA-MB-453 TNBC cells. scRNAseq was performed on untreated MDA-MB-453 cells cultured in full serum media. Cells were divided in groups based on their expression of AR, ARLow and ARHigh. (A) tSNE plot of AR levels i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bbf37a51d74bc33ff7d21665e1ab4ca
https://doi.org/10.1158/1535-7163.22522315.v1
https://doi.org/10.1158/1535-7163.22522315.v1
Autor:
Jennifer K. Richer, Jill E. Slansky, Virginia F. Borges, Kathleen Torkko, Rachel Culp-Hill, Angelo D'Alessandro, Jessica L. Christenson, Tullia C. Bruno, Lisa I. Greene
Summary of patient data
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46c8a7d8338a9ea85803eb9720207c83
https://doi.org/10.1158/1541-7786.22516348
https://doi.org/10.1158/1541-7786.22516348