Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Jennifer K Hoots"'
Autor:
Cecilia Nunez, Jennifer K Hoots, Scott T Schepers, Michael Bower, Harriet de Wit, Margaret C Wardle
Publikováno v:
PLoS ONE, Vol 17, Iss 10, p e0275027 (2022)
Many mental health disorders are characterized by an impaired ability, or willingness, to exert effort to obtain rewards. This impairment is modeled in effort-based decision tasks, and neuropharmacological studies implicate dopamine in this process.
Externí odkaz:
https://doaj.org/article/872c1b0906894f93bd5e4ff3fd61e98f
Autor:
Rajtarun Madangopal, Brendan J Tunstall, Lauren E Komer, Sophia J Weber, Jennifer K Hoots, Veronica A Lennon, Jennifer M Bossert, David H Epstein, Yavin Shaham, Bruce T Hope
Publikováno v:
eLife, Vol 8 (2019)
In abstinent drug addicts, cues formerly associated with drug-taking experiences gain relapse-inducing potency (‘incubate’) over time. Animal models of incubation may help develop treatments to prevent relapse, but these models have ubiquitously
Externí odkaz:
https://doaj.org/article/dd1c5cdadf0c42d6a522a5193016f968
Autor:
Michael T. Treadway, Scott D. Lane, Jessica A. Cooper, Margaret C. Wardle, Heather E. Webber, Victoria M. Lawlor, Paula Lopez-Gamundi, Cecilia Nunez, Jennifer K. Hoots
Publikováno v:
Psychopharmacology. 238:2815-2826
Misuse of dextroamphetamine occurs in work and recreational contexts. While acute drug effects broadly predict abuse liability, few studies have considered the relationship between acute effects and context. This study examined how individual differe
Autor:
Shruthi A. Thomas, Bruce E. Blough, David Perekopskiy, David H. Epstein, Eugene A. Kiyatkin, Jennifer K. Hoots, Ida Fredriksson, Anum Afzal, Yavin Shaham, Hannah Korah, S. Stevens Negus, Jennifer M. Bossert
Publikováno v:
Biological Psychiatry. 88:935-944
Background Maintenance treatment with opioid agonists (buprenorphine, methadone) is effective for opioid addiction but does not eliminate opioid use in all patients. We modeled maintenance treatment in rats that self-administered the prescription opi
Autor:
Jennifer K, Hoots, Heather E, Webber, Cecilia, Nunez, Jessica A, Cooper, Paula, Lopez-Gamundi, Victoria M, Lawlor, Scott D, Lane, Michael T, Treadway, Margaret C, Wardle
Publikováno v:
Psychopharmacology. 238(10)
Misuse of dextroamphetamine occurs in work and recreational contexts. While acute drug effects broadly predict abuse liability, few studies have considered the relationship between acute effects and context.This study examined how individual differen
Autor:
Scott D. Lane, Heather E. Soder, Cecilia Nunez, Victoria M. Lawlor, Paula Lopez-Gamundi, Jessica A. Cooper, Michael T. Treadway, Jennifer K. Hoots, Margaret C. Wardle
Publikováno v:
Neuropsychopharmacology
Effort-related decision-making and reward learning are both dopamine-dependent, but preclinical research suggests they depend on different dopamine signaling dynamics. Therefore, the same dose of a dopaminergic medication could have differential effe
Autor:
Sam A. Golden, Jennifer K. Hoots, Michelle Zhang, Conor Heins, Daniele Caprioli, Yavin Shaham, Marco Venniro, Marisela Morales, David H. Epstein
Publikováno v:
Nat Neurosci
Addiction treatment has not been appreciably improved by neuroscientific research. One problem is that mechanistic studies using rodent models do not incorporate volitional social factors, which play a critical role in human addiction. Here, using ra
Autor:
Michelle Zhang, Jennifer M. Bossert, Sweta Adhikary, Marco Venniro, Jennifer K. Hoots, Yavin Shaham, Ida Fredriksson
Publikováno v:
European Journal of Neuroscience. 50:2075-2085
Relapse to non-medical use of prescription opioids often occurs after exposure to places previously associated with drug use. Here, we describe a rat model of context-induced reinstatement of oxycodone seeking after repeated cycles of drug self-admin
Autor:
Yann Pelloux, Angelica Minier-Toribio, Carlo Cifani, Jennifer M. Bossert, Jennifer K. Hoots, Sweta Adhikary, Jennifer A. Martin, Yavin Shaham
Publikováno v:
Addiction Biology. 23:699-712
We recently developed a rat model of context‐induced relapse to alcohol seeking after punishment‐imposed abstinence to mimic relapse after self‐imposed abstinence due to adverse consequences of drug use. Here, we determined the model’s genera
Autor:
Yavin Shaham, Bruce T. Hope, Veronica A Lennon, Brendan J. Tunstall, Jennifer K. Hoots, Lauren E Komer, Sophia J Weber, David H. Epstein, Rajtarun Madangopal, Jennifer M. Bossert
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b6843d7a632a190c13175217a3935813
https://doi.org/10.7554/elife.44427.015
https://doi.org/10.7554/elife.44427.015