Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Jennifer K, Field"'
Autor:
Jennifer K. Field, James Bruce, Stephen Buckenmaier, Ming Yui Cheung, Melvin R. Euerby, Kim F. Haselmann, Jesper F. Lau, Dwight Stoll, Marie Sylvester, Henning Thogersen, Patrik Petersson
Publikováno v:
LCGC Europe. :440-449
This review article summarizes the results obtained from the combined efforts of a joint academic and industrial initiative to solve the real-life challenge of determining low levels of peptide-related impurities (typically 0.05–1% of the drug subs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d1a882aab0d7a92b57d128c6aeb2f45f
https://doi.org/10.56530/lcgc.eu.qp3971p2
https://doi.org/10.56530/lcgc.eu.qp3971p2
Autor:
Jennifer K. Field, Christine Hinz, Christopher M. Titman, Matthew C. Hulme, Rhona M. Cowan, Jack B. Ainsworth-McMillan, Nicolas Gilbert, Robert J. Lee, Jack Marron, Andrew Costello, Ryan E. Mewis, Melvin R. Euerby, Oliver B. Sutcliffe
This study describes the first reported development of a rapid, generic gradient Ultra-High Performance Liquid Chromatography (UHPLC) methodology with targeted triple quadrupole MS/MS using electrospray positive ionisation to detect and unambiguously
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2979041a25e931118f1a9bb0d8d2106f
https://strathprints.strath.ac.uk/81050/1/Field_etal_JPBA_2022_Guilty_by_dissociation_Part_A_Development_of_a_rapid.pdf
https://strathprints.strath.ac.uk/81050/1/Field_etal_JPBA_2022_Guilty_by_dissociation_Part_A_Development_of_a_rapid.pdf
Autor:
Ifigeneia Christopoulou, Melvin R. Euerby, Jennifer K. Field, Patrik Petersson, Paul Ferguson, Ashleigh Bell
Publikováno v:
Chromatographia. 83:1257-1267
A simple, rapid and robust protocol for the characterisation of strong cation exchange columns for the analysis of small molecular weight bases is described. A range of ten different phases were characterised, and the resultant selectivity and retent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::022a8d87467d972fcf5538585fbe68ad
https://doi.org/10.1007/s10337-020-03943-7
https://doi.org/10.1007/s10337-020-03943-7
Publikováno v:
Journal of chromatography. A. 1668
The paper describes a simple and rapid reversed-phase UHPLC method development screening strategy for the purity determination of peptide-based pharmaceuticals. The protocol utilises five disparate column and six volatile or non-volatile mobile phase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a3783da39bc1f382d26351ed0e5fd2b
https://pubmed.ncbi.nlm.nih.gov/35231862
https://pubmed.ncbi.nlm.nih.gov/35231862
Autor:
Graeme, Cochrane, Jennifer K, Field, Matthew C, Hulme, Nicolas, Gilbert, Ryan E, Mewis, Melvin R, Euerby, Oliver B, Sutcliffe
Publikováno v:
Journal of Pharmaceutical and Biomedical Analysis. 216:114797
Supercritical Fluid Chromatography (SFC-UV) employing a carbon dioxide (CO 2) and 10 mM ammonium acetate in MeOH-water (95:5 v/v) gradient provides a rapid analysis (t G
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81a83f2a75dfe2e024d4803b2d058c26
https://doi.org/10.1016/j.jpba.2022.114797
https://doi.org/10.1016/j.jpba.2022.114797
A protocol was defined which utilised peptides as probes for the characterisation of reversed phase chromatography peptide separation systems. These peptide probes successfully distinguished between differing stationary phases through the probe's hyd
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9966eac4d1426623b6e678933eca0a6b
https://strathprints.strath.ac.uk/69134/1/Field_etal_JCA_2019_Investigation_into_reversed_phase_chromatography_peptide_separation_systems_part_I.pdf
https://strathprints.strath.ac.uk/69134/1/Field_etal_JCA_2019_Investigation_into_reversed_phase_chromatography_peptide_separation_systems_part_I.pdf
The robustness of the Peptide Reversed Phase Chromatography (RPC) Column Characterisation Protocol was evaluated using reduced factorial design, to ascertain the degree of control required for parameters including temperature, flow rate, dwell volume
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8801108083c4bafaa1292d5a36fb18f
https://strathprints.strath.ac.uk/69133/1/Field_etal_JOCA_2019_Investigation_into_reversed_phase_chromatography_peptide_separation.pdf
https://strathprints.strath.ac.uk/69133/1/Field_etal_JOCA_2019_Investigation_into_reversed_phase_chromatography_peptide_separation.pdf
Publikováno v:
Journal of Chromatography A. 1641:461986
The differentiation of mobile phase compositions between sub-classes which exhibit distinct chromatographic selectivity (i.e. termed characterisation) towards a range of peptide probes with diverse functionality and hence the possibility for multi-mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94a3eb0378f15a841fc25bc20ef0011f
https://doi.org/10.1016/j.chroma.2021.461986
https://doi.org/10.1016/j.chroma.2021.461986
Publikováno v:
Journal of Chromatography A. 1622:461093
The Peptide RPC Column Characterisation Protocol was applied to 38 stationary phases, varying in ligand chemistry, base silica, end capping and pore size, which are suitable for the analysis of peptides. The protocol at low and intermediate pH is bas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::108a79601f0f73c1e83ff51a273e4e67
https://doi.org/10.1016/j.chroma.2020.461093
https://doi.org/10.1016/j.chroma.2020.461093