Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Jennifer Just"'
Autor:
Danny Baltissen, Charlotte S. Bold, Lena Rehra, Marija Banićević, Justus Fricke, Jennifer Just, Susann Ludewig, Christian J. Buchholz, Martin Korte, Ulrike C. Müller
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 17 (2023)
The Tau protein can be phosphorylated by numerous kinases. In Alzheimer’s disease (AD) hyperphosphorylated Tau species accumulate as neurofibrillary tangles that constitute a major hallmark of AD. AD is further characterized by extracellular Aβ pl
Externí odkaz:
https://doaj.org/article/242ab636d58b405ca9545a37ecf5a283
Publikováno v:
PeerJ Computer Science, Vol 7, p e502 (2021)
Background In the collaborative business environment, blockchain coupled with smart contract removes the reliance on a central system and offers data integrity which is crucial when the transacting parties rely on the shared data. The acceptance of s
Externí odkaz:
https://doaj.org/article/78496cff07e5448f822835cc856f3eea
Autor:
Saskia Elgün, Jakob Waibel, Christiane Kehrer, Diane van Rappard, Judith Böhringer, Stefanie Beck-Wödl, Jennifer Just, Ludger Schöls, Nicole Wolf, Ingeborg Krägeloh-Mann, Samuel Groeschel
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 14, Iss 1, Pp 1-10 (2019)
Abstract Background Metachromatic Leukodystrophy (MLD) is a rare autosomal-recessive lysosomal storage disorder caused by mutations in the ARSA gene. While interventional trials often use untreated siblings as controls, the genotype-phenotype correla
Externí odkaz:
https://doaj.org/article/18973d713b264693bee6cb2ec96b1533
Autor:
Tim W. Rattay, Jennifer Just, Benjamin Röben, Holger Hengel, Rebecca Schüle, Matthis Synofzik, Anne S. Söhn, Natalie Winter, Nele Dammeier, Ludger Schöls, Alexander Grimm
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 13, Iss 1, Pp 1-7 (2018)
Abstract Objective High-resolution nerve ultrasound (HRUS) is a painless tool to quickly evaluate peripheral nerve morphology in vivo. This study set out to characterize peripheral nerve involvement in X-linked adrenomyeloneuropathy (AMN) by HRUS. Me
Externí odkaz:
https://doaj.org/article/4183a8e16cef48e38a581ce04002e586
Autor:
Jan Kern, Janina Gburek-Augustat, Klaus Harzer, Miriam Stampfer, I. Kraegeloh-Mann, Samuel Groeschel, Stefanie Beck-Woedl, Jennifer Just
Publikováno v:
Neuropediatrics. 51:037-044
Aim The study aims to describe cerebral MRI in different onset forms of Niemann-Pick type C (NPC). Systematic MRI analyses in this rare lysosomal storage disease are lacking in the infantile and juvenile onset forms. Methods Thirty-two cerebral MRI s
Autor:
Charlotte Bold, Ulrike Müller, Kristin Metzdorf, Kristin Michaelsen-Preusse, Martin Korte, Susann Ludewig, Jennifer Just, Ulrike Herrmann
Publikováno v:
Proc Natl Acad Sci U S A
Alterations in Ca(2+) homeostasis have been reported in several in vitro and in vivo studies using mice expressing the Alzheimer’s disease–associated transgenes, presenilin and the amyloid precursor protein (APP). While intense research focused o
Autor:
Klaus Scheffler, Benjamin Bender, Till-Karsten Hauser, Jennifer Just, Ulrike Ernemann, Vinod Kumar, Wolfgang Grodd, Tobias Lindig, Bettina Brendel, Matthis Synofzik, Uwe Klose, Ludger Schöls
Publikováno v:
The Cerebellum 18(3), 435-447 (2019). doi:10.1007/s12311-019-1008-z
The Cerebellum
The Cerebellum
Whole-brain voxel-based morphometry (VBM) studies revealed patterns of patchy atrophy within the cerebellum of Friedreich’s ataxia patients, missing clear clinico-anatomic correlations. Studies so far are lacking an appropriate registration to the
Autor:
Alexander Grimm, Benjamin Roeben, Matthis Synofzik, Peter Pöschl, Holger Hengel, Jennifer Just, Friedemann Bender, Ludger Schöls
Publikováno v:
Clinical neurophysiology 131(8), 1798-1803 (2020). doi:10.1016/j.clinph.2020.04.162
Objective To characterize peripheral nerve morphology in cerebrotendinous xanthomatosis (CTX) patients using high-resolution ultrasound (HRUS) in vivo. We hypothesized that nerve enlargements might be present in CTX as a result of accumulation of abn
Autor:
Matthis Synofzik, Vinay Jayaram, Jennifer Just, Tatiana Fomina, Bernhard Schölkopf, Moritz Grosse-Wentrup, Matthias R. Hohmann, Ludger Schöls, Theresa Emde
Publikováno v:
Clinical neurophysiology 129(2), 406-408 (2018). doi:10.1016/j.clinph.2017.11.013
The alpha peak frequency (APF) of the human electroencephalogram (EEG) is a reliable neurophysiological marker for cognitive abilities. In these case series, we document a shift of the APF towards the lower end of the EEG spectrum in two completely l
Autor:
Peter Bauer, Jennifer Just, Ludger Schöls, Stefan A. Kolb, Juan V. Torres Martin, Zofia Fleszar, Matthis Synofzik
Publikováno v:
Journal of Neurology
Journal of neurology 263(10), 1911-1918 (2016). doi:10.1007/s00415-016-8178-0
Journal of neurology 263(10), 1911-1918 (2016). doi:10.1007/s00415-016-8178-0
Niemann–Pick disease type C (NP-C) is a rare multisystemic lysosomal disorder which, albeit treatable, is still starkly underdiagnosed. As NP-C features early onset ataxia (EOA) in 85–90 % of cases, EOA presents a promising target group for undia