Zobrazeno 1 - 10
of 82
pro vyhledávání: '"Jennifer J. Schlezinger"'
Autor:
Partho Sen, Yong Fan, Jennifer J. Schlezinger, Stanislav D. Ehrlich, Thomas F. Webster, Tuulia Hyötyläinen, Oluf Pedersen, Matej Orešič
Publikováno v:
Environment International, Vol 186, Iss , Pp 108569- (2024)
Environmental toxicants (ETs) are associated with adverse health outcomes. Here we hypothesized that exposures to ETs are linked with obesity and insulin resistance partly through a dysbiotic gut microbiota and changes in the serum levels of secondar
Externí odkaz:
https://doaj.org/article/f376be16f4364257b24a48f878d043eb
Autor:
Emily H. Pennoyer, Wendy Heiger-Bernays, Rudolf Aro, Leo W. Y. Yeung, Jennifer J. Schlezinger, Thomas F. Webster
Publikováno v:
Toxics, Vol 11, Iss 5, p 416 (2023)
Organofluorines occur in human serum as complex mixtures of known and unidentified compounds. Human biomonitoring traditionally uses targeted analysis to measure the presence of known and quantifiable per- and polyfluoroalkyl substances (PFAS) in ser
Externí odkaz:
https://doaj.org/article/10cbdae197344477996a489ee6571f8a
Publikováno v:
Environmental Health, Vol 18, Iss 1, Pp 1-15 (2019)
Abstract Background Humans are exposed to a complex mixture of environmental chemicals that impact bone and metabolic health, and traditional exposure assessments struggle to capture these exposure scenarios. Peroxisome proliferator activated recepto
Externí odkaz:
https://doaj.org/article/25660c91784e47a7862edca9af2afe4d
Autor:
Supraja Narasimhan, Elizabeth Stanford Zulick, Olga Novikov, Ashley J. Parks, Jennifer J. Schlezinger, Zhongyan Wang, Fabrice Laroche, Hui Feng, Francesca Mulas, Stefano Monti, David H. Sherr
Publikováno v:
International Journal of Molecular Sciences, Vol 19, Iss 5, p 1388 (2018)
We have postulated that the aryl hydrocarbon receptor (AHR) drives the later, more lethal stages of some cancers when chronically activated by endogenous ligands. However, other studies have suggested that, under some circumstances, the AHR can oppos
Externí odkaz:
https://doaj.org/article/75f920ff3507453dab4ee274a2be4b58
Autor:
Thomas F. Webster, Sirkku Jäntti, Panu K. Luukkonen, Hannele Yki-Järvinen, Sami Qadri, Jennifer J. Schlezinger, Partho Sen, Tuulia Hyötyläinen, Oddny Ragnarsdottir, Johanna Arola, Matej Orešič, Aidan McGlinchey, Anne Juuti
Background & aims: Recent experimental models and epidemiological studies suggest that specific environmental contaminants (ECs) contribute to the initiation and pathology of nonalcoholic fatty liver disease (NAFLD). However, the underlying mechanism
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12f3171cdf4042f896110a691c6ee118
http://hdl.handle.net/10138/342175
http://hdl.handle.net/10138/342175
Autor:
Nina Horowitz, Jack Page, Elise F. Morgan, Jennifer J. Schlezinger, Darlene Lu, Serkalem Demissie, Yuriy O. Alekseyev, Marc E. Lenburg, Louis C. Gerstenfeld, Beth Bragdon, M. Zachary Webster, Amira I. Hussein, Dana Daukss, Yu Liu, Adam C. Gower
Publikováno v:
JBMR Plus. 6
Time is a central element of the sexual dimorphic patterns of development, pathology, and aging of the skeleton. Because the transcriptome is a representation of the phenome, we hypothesized that both sex and sex-specific temporal, transcriptomic dif
Publikováno v:
Toxicology
Human exposure to per- and polyfluoroalkyl substances (PFAS) is ubiquitous, with mixtures of PFAS detected in drinking water, food, household dust, and other exposure sources. Animal toxicity studies and human epidemiology indicate that PFAS may act
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::723b793e89633b8d60297122ecef1f4b
https://europepmc.org/articles/PMC8692422/
https://europepmc.org/articles/PMC8692422/
Publikováno v:
Toxicol Appl Pharmacol
Risk factors for poor bone quality include estrogen loss at menopause, a high fat diet and exposures to drugs/chemicals that activate peroxisome proliferator activated receptor gamma (PPARγ). We observed that the PPARγ and retinoid X receptor dual
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df3480b0196bc013b3773e237dfbce81
https://europepmc.org/articles/PMC8545923/
https://europepmc.org/articles/PMC8545923/
Autor:
Patrizia Bovolin, Vesna A. Chappell, Heather M. Stapleton, Stacey L. Krager, Stephanie Kim, Fahmi Mesmar, Erika Cottone, Mariana F. Fernández, Shelley A. Tischkau, Ella Atlas, Sibylle Ermler, Christopher D. Kassotis, Jennifer J. Schlezinger, Suzanne E. Fenton, Yong Pu, Karen Leingartner, Astrid Saraceni, Johannes Völker, Rosaria Scandiffio, Juliette Legler, Maria Bondesson, Almudena Veiga-Lopez, Kate Hoffman
Publikováno v:
Toxicology
The 3T3-L1 murine pre-adipocyte line is an established cell culture model for screening Metabolism Disrupting Chemicals (MDCs). Despite a need to accurately identify MDCs for further evaluation, relatively little research has been performed to compre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::766f268e7a6f6b24f1b6f1e11b75e6c4
https://europepmc.org/articles/PMC8453119/
https://europepmc.org/articles/PMC8453119/
Autor:
Gloria B. Post, Linda S. Birnbaum, Jamie C. DeWitt, Helen Goeden, Wendy J. Heiger-Bernays, Jennifer J. Schlezinger
Publikováno v:
Regulatory Toxicology and Pharmacology. 134:105240